Paper · 42938348

Long Non-Coding RNA LINC01614 Promotes Aggressive Phenotypes and Ferroptosis Resistance in Papillary Thyroid Cancer Through a Putative miR-4521/IGF2/PI3K-AKT Signaling Axis.

Quaranto D and 9 others. Genes (Basel), 2026.

11 sourcespapers-2026-11-12-0.1.0

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ConductScience Library. Long Non-Coding RNA LINC01614 Promotes Aggressive Phenotypes and Ferroptosis Resistance in Papillary Thyroid Cancer Through a Putative miR-4521/IGF2/PI3K-AKT Signaling Axis. Papers, record 42938348. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/42938348

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Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title: Long Non-Coding RNA LINC01614 Promotes Aggressive Phenotypes and Ferroptosis Resistance in Papillary Thyroid Cancer Through a Putative miR-4521/IGF2/PI3K-AKT Signaling Axis.
Journal: Genes (Basel)
Year: 2026
Publication types: Journal Article
PubMed: https://pubmed.ncbi.nlm.nih.gov/42938348/
DOI: https://doi.org/10.3390/genes17101232
PMC: https://pmc.ncbi.nlm.nih.gov/articles/PMC13704247/
The journal: https://conductscience.org/library/journal-index/101551097
Revised in PubMed: 2026-10-28

Source PubMed

Authors10

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

Order	Author	Forename	ORCID iD
1	Quaranto D	Danielle
2	DeSouza NR	Nicole R
3	Carnazza M	Michelle
4	Dadafarin S	Sina	https://orcid.org/0000-0002-7956-0419
5	Moscatello A	Augustine
6	Iacob C	Codrin
7	Islam HK	Humayun K
8	Li XM	Xiu-Min
9	Tiwari RK	Raj K
10	Geliebter J	Jan	https://orcid.org/0000-0002-2944-7960

Source PubMed

Topics15

NLM's MeSH indexing of the paper, its major topics first.

MeSH term	Major
Ferroptosis	Major topic
Thyroid Cancer, Papillary	Major topic
RNA, Long Noncoding	Major topic
Thyroid Neoplasms	Major topic
MicroRNAs	Major topic
Humans
Proto-Oncogene Proteins c-akt
Signal Transduction
Cell Line, Tumor
Gene Expression Regulation, Neoplastic
Phosphatidylinositol 3-Kinases
Cell Proliferation
Insulin-Like Growth Factor II
Cell Movement
Phenotype

Source PubMed

Grants1

Each grant PubMed's record writes, matched to the NIH project NIH's grant and paper links name for this paper, and each of those links the record does not write.

Grant, as the record writes it	Agency	Country	NIH project	Stated by
130380	New York State Department of Health			PubMed

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Trials0

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None in this release.

Comments and corrections0

PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.

None in this release.

References23

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

Order	PMID	Title	Journal	Year	In Papers	Source
1	25,417,114	Integrated genomic characterization of papillary thyroid carcinoma.	Cell	2014	https://conductscience.org/library/papers/25417114	PubMed
2	33,407,516	Hypoxia downregulated miR-4521 suppresses gastric carcinoma progression through regulation of IGF2 and FOXM1.	Mol Cancer	2021	https://conductscience.org/library/papers/33407516	PubMed
3	23,429,735	Molecular pathogenesis and mechanisms of thyroid cancer.	Nat Rev Cancer	2013	https://conductscience.org/library/papers/23429735	PubMed
4	38,562,143	Regulation of ferroptosis by PI3K/Akt signaling pathway: a promising therapeutic axis in cancer.	Front Cell Dev Biol	2024	https://conductscience.org/library/papers/38562143	PubMed
5	24,439,385	Regulation of ferroptotic cancer cell death by GPX4.	Cell	2014	https://conductscience.org/library/papers/24439385	PubMed
6	36,944,609	The interaction between ferroptosis and inflammatory signaling pathways.	Cell Death Dis	2023	https://conductscience.org/library/papers/36944609	PubMed
7	33,000,412	Cystine transporter SLC7A11/xCT in cancer: ferroptosis, nutrient dependency, and cancer therapy.	Protein Cell	2021	https://conductscience.org/library/papers/33000412	PubMed
8	33,353,982	Gene regulation by long non-coding RNAs and its biological functions.	Nat Rev Mol Cell Biol	2021	https://conductscience.org/library/papers/33353982	PubMed
9	33,495,651	Ferroptosis: mechanisms, biology and role in disease.	Nat Rev Mol Cell Biol	2021	https://conductscience.org/library/papers/33495651	PubMed
10	10,405,160	Ratio-fluorescence microscopy of lipid oxidation in living cells using C11-BODIPY(581/591).	FEBS Lett	1999	https://conductscience.org/library/papers/10405160	PubMed

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Cited by0

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Genes0

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None in this release.

Drugs0

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None in this release.

Data0

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None in this release.

Data dates

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PubMed: 2026-11-06; PubMed
iCite: 2026-11-05; iCite
PMC's ID file: 2026-11-05; PMC's ID file
NIH RePORTER's grant and paper links: 2026-11-01; NIH RePORTER's grant and paper links
Trials: 2026-11-12
Gene search: 2026-11-11
Pipelines: 2026-09-18

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iCiteCC BY 4.0
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NIH RePORTER's grant and paper linksPublic domain
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PMC's ID filePublic domain (US government)
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PubTator 3Public domain
UniProtCC BY 4.0

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ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
ClinicalTrials.govnone stated
HGNCCC0: https://www.genenames.org/about/license/
iCiteCC BY 4.0
NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
PubMedNLM's terms
PubTator 3Public domain
UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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