Paper · 33495651
Ferroptosis: mechanisms, biology and role in disease.
Jiang X and 2 others. Nat Rev Mol Cell Biol, 2021. Cited by 6,572 papers, by iCite.
11 sourcespapers-2026-11-12-0.1.0
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ConductScience Library. Ferroptosis: mechanisms, biology and role in disease. Papers, record 33495651. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/33495651
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Paper
PubMed's record of the paper, with iCite's citation figures. No abstract is shown.
- Publication types
- Journal Article, Research Support, N.I.H., Extramural, Research Support, Non-U.S. Gov't, Review
- PubMed
Topics8
NLM's MeSH indexing of the paper, its major topics first.
| MeSH term | Major |
|---|---|
| Ferroptosis | Major topic |
| Neoplasms | Major topic |
| Animals | |
| Gene Regulatory Networks | |
| Humans | |
| Lipid Peroxidation | |
| Oxidation-Reduction | |
| Reproducibility of Results |
Source PubMed
Grants6
Each grant PubMed's record writes, matched to the NIH project NIH's grant and paper links name for this paper, and each of those links the record does not write.
| Grant, as the record writes it | Agency | Country | NIH project | Stated by | Source |
|---|---|---|---|---|---|
| R35 CA209896 | NCI NIH HHS | United States | R35CA209896 | PubMed and NIH | NIH RePORTER |
| P30 CA008748 | NCI NIH HHS | United States | P30CA008748 | PubMed and NIH | NIH RePORTER |
| R01 CA166413 | NCI NIH HHS | United States | R01CA166413 | PubMed and NIH | NIH RePORTER |
| R33 NS109407 | NINDS NIH HHS | United States | R61NS109407 | PubMed and NIH | NIH RePORTER |
| R01 CA204232 | NCI NIH HHS | United States | R01CA204232 | PubMed and NIH | NIH RePORTER |
| P01CA087497 | NIH | NIH RePORTER |
Trials0
The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.
None in this release.
Comments and corrections0
PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.
None in this release.
References189
The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.
| Order | PMID | Title | Journal | Year | In Papers | Source |
|---|---|---|---|---|---|---|
| 1 | 31,899,616 | Radiation-Induced Lipid Peroxidation Triggers Ferroptosis and Synergizes with Ferroptosis Inducers. | ACS Chem Biol | 2020 | https://conductscience.org/library/papers/31899616 | PubMed |
| 2 | 26,019,222 | SLC7A11 expression is associated with seizures and predicts poor survival in patients with malignant glioma. | Sci Transl Med | 2015 | https://conductscience.org/library/papers/26019222 | PubMed |
| 3 | 16,144,837 | Redox imbalance in cystine/glutamate transporter-deficient mice. | J Biol Chem | 2005 | https://conductscience.org/library/papers/16144837 | PubMed |
| 4 | 30,266,679 | Striking while the iron is hot: Iron metabolism and ferroptosis in neurodegeneration. | Free Radic Biol Med | 2019 | https://conductscience.org/library/papers/30266679 | PubMed |
| 5 | 25,824,823 | T cell lipid peroxidation induces ferroptosis and prevents immunity to infection. | J Exp Med | 2015 | https://conductscience.org/library/papers/25824823 | PubMed |
| 6 | 31,056,284 | Selenium Drives a Transcriptional Adaptive Program to Block Ferroptosis and Treat Stroke. | Cell | 2019 | https://conductscience.org/library/papers/31056284 | PubMed |
| 7 | 30,202,049 | BAP1 links metabolic regulation of ferroptosis to tumour suppression. | Nat Cell Biol | 2018 | https://conductscience.org/library/papers/30202049 | PubMed |
| 8 | 32,231,263 | Reactive oxygen species (ROS) as pleiotropic physiological signalling agents. | Nat Rev Mol Cell Biol | 2020 | https://conductscience.org/library/papers/32231263 | PubMed |
| 9 | 25,385,600 | Synchronized renal tubular cell death involves ferroptosis. | Proc Natl Acad Sci U S A | 2014 | https://conductscience.org/library/papers/25385600 | PubMed |
| 10 | 30,787,033 | A major role for ferroptosis in Mycobacterium tuberculosis-induced cell death and tissue necrosis. | J Exp Med | 2019 | https://conductscience.org/library/papers/30787033 | PubMed |
1 to 10 of 189
See all 189 referencesCited by4,256
The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 6,572 citations.
| PMID | Title | Journal | Year | In Papers | Source |
|---|---|---|---|---|---|
| 42,989,889 | Smart Soup Ameliorates Cognitive Dysfunction in Diabetic Encephalopathy by Inhibiting Hippocampal Ferroptosis and Restoring Mitophagic Balance. | Biomed Res Int | 2026 | https://conductscience.org/library/papers/42989889 | PubMed |
| 42,989,090 | Madecassic acid orchestrates DDX17-dependent pathway suppression of ferroptosis to mitigate myocardial ischemic/reperfusion injury. | Cell Mol Biol Lett | 2026 | https://conductscience.org/library/papers/42989090 | PubMed |
| 42,985,491 | LCN2: Potential Targets for Cancer via Ferroptosis-Related Pathways. | Oncol Res | 2026 | https://conductscience.org/library/papers/42985491 | PubMed |
| 42,984,892 | Keratinocyte TMEM79 protects early life epidermal homeostasis and restrains STING-dependent skin inflammation. | PNAS Nexus | 2026 | https://conductscience.org/library/papers/42984892 | PubMed |
| 42,983,471 | NEDD9 confers ferroptosis resistance in liver cancer by inhibiting autophagy via the AKT‑mTOR signaling pathway. | Biol Direct | 2026 | https://conductscience.org/library/papers/42983471 | PubMed |
| 42,983,029 | Atf3 Regulates Spermatogenesis by Mediating Ferroptosis During Testicular Heat Exposure. | Reprod Sci | 2026 | https://conductscience.org/library/papers/42983029 | PubMed |
| 42,979,315 | A peptide-based nano-PROTAC synergistically driving ferroptosis-immunotherapy in triple-negative breast cancer. | Acta Pharm Sin B | 2026 | https://conductscience.org/library/papers/42979315 | PubMed |
| 42,978,988 | Magnetic nanoplatforms at the tumor redox interface: from catalytic ROS amplification to ferroptosis and multimodal cancer therapy. | Front Oncol | 2026 | https://conductscience.org/library/papers/42978988 | PubMed |
| 42,978,620 | Epithelial-mesenchymal plasticity is associated with transcriptional variation in regulated cell death and immune signaling programs in lung adenocarcinoma. | Front Cell Dev Biol | 2026 | https://conductscience.org/library/papers/42978620 | PubMed |
| 42,974,515 | Targeting asparagine synthetase triggers ferroptosis and suppresses endometrial cancer growth via Atractylenolide II. | J Transl Int Med | 2026 | https://conductscience.org/library/papers/42974515 | PubMed |
1 to 10 of 4,256
See all 4,256 cited byGenes18
The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.
| Gene | NCBI Gene ID | Linked by | In Genes | Source |
|---|---|---|---|---|
| ACSL4 | 2,182 | PubTator's text mining | https://conductscience.org/library/genes/2182 | NCBI Gene |
| ATM | 472 | PubTator's text mining | https://conductscience.org/library/genes/472 | NCBI Gene |
| CD274 | 29,126 | PubTator's text mining | https://conductscience.org/library/genes/29126 | NCBI Gene |
| CD8A | 925 | PubTator's text mining | https://conductscience.org/library/genes/925 | NCBI Gene |
| GPX1 | 2,876 | PubTator's text mining | https://conductscience.org/library/genes/2876 | NCBI Gene |
| GPX3 | 2,878 | PubTator's text mining | https://conductscience.org/library/genes/2878 | NCBI Gene |
| GPX4 | 2,879 | PubTator's text mining | https://conductscience.org/library/genes/2879 | NCBI Gene |
| GRSF1 | 2,926 | PubTator's text mining | https://conductscience.org/library/genes/2926 | NCBI Gene |
| GSTK1 | 373,156 | PubTator's text mining | https://conductscience.org/library/genes/373156 | NCBI Gene |
| HERC5 | 51,191 | PubTator's text mining | https://conductscience.org/library/genes/51191 | NCBI Gene |
1 to 10 of 18
See all 18 genesDrugs0
The drugs whose trials, in the Pipelines release, list the paper.
None in this release.
Data0
The data bank entries PubMed's record names. Trial numbers are under Trials.
None in this release.
Data dates
The date of each source this release read.
- Trials
- 2026-11-12
- Gene search
- 2026-11-11
- Pipelines
- 2026-09-18
Sources 11
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- HGNCCC0
- iCiteCC BY 4.0
- NCBI GenePublic domain (US government)
- NIH RePORTER's grant and paper linksPublic domain
- Open TargetsCC0 1.0
- PMC's ID filePublic domain (US government)
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- HGNCCC0: https://www.genenames.org/about/license/
- iCiteCC BY 4.0
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
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