Paper · 42979455
The conformational-condensate code of GRB2: State switching, spatial organization, and therapeutic windows.
Zhang J and 7 others. Acta Pharm Sin B, 2026.
11 sourcespapers-2026-11-12-0.1.0
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ConductScience Library. The conformational-condensate code of GRB2: State switching, spatial organization, and therapeutic windows. Papers, record 42979455. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/42979455
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Paper
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- Title
- The conformational-condensate code of GRB2: State switching, spatial organization, and therapeutic windows.
- Journal
- Acta Pharm Sin B
- Year
- 2026
- Publication types
- Journal Article, Review
- Revised in PubMed
- 2026-11-05
Source PubMed
Topics0
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Comments and corrections0
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References230
The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.
| Order | PMID | Title | Journal | Year | In Papers | Source |
|---|---|---|---|---|---|---|
| 1 | 11,055,351 | Structure-based design and synthesis of phosphinate isosteres of phosphotyrosine for incorporation in Grb2-SH2 domain inhibitors. Part 1. | Bioorg Med Chem Lett | 2000 | https://conductscience.org/library/papers/11055351 | PubMed |
| 2 | 11,084,343 | Interaction of EGF receptor and grb2 in living cells visualized by fluorescence resonance energy transfer (FRET) microscopy. | Curr Biol | 2000 | https://conductscience.org/library/papers/11084343 | PubMed |
| 3 | 12,688,310 | High affinity molecules disrupting GRB2 protein complexes as a therapeutic strategy for chronic myelogenous leukaemia. | Leuk Lymphoma | 2003 | https://conductscience.org/library/papers/12688310 | PubMed |
| 4 | 16,369,543 | A role for the scaffolding adapter GAB2 in breast cancer. | Nat Med | 2006 | https://conductscience.org/library/papers/16369543 | PubMed |
| 5 | 9,390,033 | Grb2 overexpression in nuclei and cytoplasm of human breast cells: a histochemical and biochemical study of normal and neoplastic mammary tissue specimens. | J Pathol | 1997 | https://conductscience.org/library/papers/9390033 | PubMed |
| 6 | 34,170,647 | Tirzepatide versus Semaglutide Once Weekly in Patients with Type 2 Diabetes. | N Engl J Med | 2021 | https://conductscience.org/library/papers/34170647 | PubMed |
| 7 | 19,240,254 | Downregulation of Grb2 contributes to the insulin-sensitizing effect of calorie restriction. | Am J Physiol Endocrinol Metab | 2009 | https://conductscience.org/library/papers/19240254 | PubMed |
| 8 | 40,327,534 | Shc1 cooperates with Frs2 and Shp2 to recruit Grb2 in FGF-induced lens development. | Elife | 2025 | https://conductscience.org/library/papers/40327534 | PubMed |
| 9 | 20,883,498 | Docking proteins. | FEBS J | 2010 | https://conductscience.org/library/papers/20883498 | PubMed |
| 10 | 15,962,011 | Sprouty2 acts at the Cbl/CIN85 interface to inhibit epidermal growth factor receptor downregulation. | EMBO Rep | 2005 | https://conductscience.org/library/papers/15962011 | PubMed |
1 to 10 of 230
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Data0
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Data dates
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- Trials
- 2026-11-12
- Gene search
- 2026-11-11
- Pipelines
- 2026-09-18
Sources 11
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- HGNCCC0
- iCiteCC BY 4.0
- NCBI GenePublic domain (US government)
- NIH RePORTER's grant and paper linksPublic domain
- Open TargetsCC0 1.0
- PMC's ID filePublic domain (US government)
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- HGNCCC0: https://www.genenames.org/about/license/
- iCiteCC BY 4.0
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
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