Paper · 7053378

Heparin with two binding sites for antithrombin or platelet factor 4.

Jordan RE and 3 others. J Biol Chem, 1982. Cited by 100 papers, by iCite.

11 sourcespapers-2026-11-12-0.1.0

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ConductScience Library. Heparin with two binding sites for antithrombin or platelet factor 4. Papers, record 7053378. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/7053378

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Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title: Heparin with two binding sites for antithrombin or platelet factor 4.; PubMed
Journal: J Biol Chem; PubMed
Year: 1982; PubMed
Publication types: Journal Article, Research Support, Non-U.S. Gov't, Research Support, U.S. Gov't, P.H.S.; PubMed
PubMed: https://pubmed.ncbi.nlm.nih.gov/7053378/; PubMed
The journal: https://conductscience.org/library/journal-index/2985121R; PubMed
Citations, by iCite: 100; iCite
Relative citation ratio, by iCite: 3.21; iCite
Revised in PubMed: 2021-02-10; PubMed

Authors4

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

Order	Author	Forename
1	Jordan RE	R E
2	Favreau LV	L V
3	Braswell EH	E H
4	Rosenberg RD	R D

Source PubMed

Topics12

NLM's MeSH indexing of the paper, its major topics first.

MeSH term	Major
Antithrombins	Major topic
Blood Coagulation Factors	Major topic
Heparin	Major topic
Platelet Factor 4	Major topic
Binding Sites
Chromatography, Affinity
Concanavalin A
Humans
Kinetics
Molecular Weight
Protein Binding
Sepharose

Source PubMed

Grants2

Each grant PubMed's record writes, matched to the NIH project NIH's grant and paper links name for this paper, and each of those links the record does not write.

Grant, as the record writes it	Agency	Country	NIH project	Stated by	Source
HLB-19131	NHLBI NIH HHS	United States		PubMed	PubMed
			R01HL019131	NIH	NIH RePORTER

Trials0

The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.

None in this release.

Comments and corrections0

PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.

None in this release.

References0

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

None in this release.

Cited by22

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 100 citations.

PMID	Title	Journal	Year	In Papers	Source
41,946,916	Heparin microarray-based specific interaction assay of marine sulfated polysaccharides with antithrombin Ⅲ.	Commun Chem	2026	https://conductscience.org/library/papers/41946916	PubMed
36,200,072	Interactions of marine sulfated glycans with antithrombin and platelet factor 4.	Front Mol Biosci	2022	https://conductscience.org/library/papers/36200072	PubMed
35,915,630	Commercial Low Molecular Weight Heparins - Patent Ecosystem and Technology Paradigm for Quality Characterization.	J Pharm Innov	2022	https://conductscience.org/library/papers/35915630	PubMed
28,282,887	New Insights in Thrombin Inhibition Structure-Activity Relationships by Characterization of Octadecasaccharides from Low Molecular Weight Heparin.	Molecules	2017	https://conductscience.org/library/papers/28282887	PubMed
23,843,463	Heparin dodecasaccharide containing two antithrombin-binding pentasaccharides: structural features and biological properties.	J Biol Chem	2013	https://conductscience.org/library/papers/23843463	PubMed
19,431,694	Polyelectrolyte charge corrected molecular weight and effective charge by sedimentation.	Biophys J	1987	https://conductscience.org/library/papers/19431694	PubMed
17,176,096	Interaction of heparin with two synthetic peptides that neutralize the anticoagulant activity of heparin.	Biochemistry	2006	https://conductscience.org/library/papers/17176096	PubMed
9,881,776	Structure-function relations of heparin-mimetic sulfated xylan oligosaccharides: inhibition of human immunodeficiency virus-1 infectivity in vitro.	Glycoconj J	1998	https://conductscience.org/library/papers/9881776	PubMed
6,961,402	Circular dichroism spectroscopy of heparin-antithrombin interactions.	Proc Natl Acad Sci U S A	1982	https://conductscience.org/library/papers/6961402	PubMed
6,746,897	Acceleration of thrombin-antithrombin complex formation in rat hindquarters via heparinlike molecules bound to the endothelium.	J Clin Invest	1984	https://conductscience.org/library/papers/6746897	PubMed

1 to 10 of 22

See all 22 cited by

Genes2

The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.

Gene	NCBI Gene ID	Linked by	In Genes	Source
PF4	5,196	PubTator's text mining	https://conductscience.org/library/genes/5196	NCBI Gene
SERPINC1	462	PubTator's text mining	https://conductscience.org/library/genes/462	NCBI Gene

Drugs0

The drugs whose trials, in the Pipelines release, list the paper.

None in this release.

Data0

The data bank entries PubMed's record names. Trial numbers are under Trials.

None in this release.

Data dates

The date of each source this release read.

PubMed: 2026-11-06; PubMed
iCite: 2026-11-05; iCite
PMC's ID file: 2026-11-05; PMC's ID file
NIH RePORTER's grant and paper links: 2026-11-01; NIH RePORTER's grant and paper links
Trials: 2026-11-12
Gene search: 2026-11-11
Pipelines: 2026-09-18

Sources 11

ChEMBL, through Open TargetsCC BY-SA 3.0
ClinicalTrials.govNo license stated
HGNCCC0
iCiteCC BY 4.0
NCBI GenePublic domain (US government)
NIH RePORTER's grant and paper linksPublic domain
Open TargetsCC0 1.0
PMC's ID filePublic domain (US government)
PubMedNLM's terms
PubTator 3Public domain
UniProtCC BY 4.0

Each source's terms

ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
ClinicalTrials.govnone stated
HGNCCC0: https://www.genenames.org/about/license/
iCiteCC BY 4.0
NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
PubMedNLM's terms
PubTator 3Public domain
UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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