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Paper770504

Survival of isolated human islets of Langerhans maintained in tissue culture.

Andersson A and 7 others. J Clin Invest, 1976. Cited by 95 papers, by iCite.

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ConductScience Library. Survival of isolated human islets of Langerhans maintained in tissue culture. Papers, record 770504. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/770504

Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title
Survival of isolated human islets of Langerhans maintained in tissue culture.
PubMed
Journal
J Clin Invest
PubMed
Year
1976
PubMed
Publication types
Journal Article
PubMed
Citations, by iCite
95
iCite
Relative citation ratio, by iCite
3.51
iCite
Revised in PubMed
2018-11-13
PubMed

Authors8

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

OrderAuthorForenameKindORCID iD
1Andersson AA
2Borg HH
3Groth CGC G
4Gunnarsson RR
5Hellerström CC
6Lundgren GG
7Westman JJ
8Ostman JJ

Source PubMed

Topics8

NLM's MeSH indexing of the paper, its major topics first.

MeSH termMajor
Islets of LangerhansMajor topic
Culture Techniques
Glucagon
Glucose
Humans
Insulin
Microscopy, Electron
Oxygen Consumption

Source PubMed

References34

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

OrderPMIDTitleJournalYearIn PapersSource
1122,797Transplantation of islets of Langerhans in diabetic rhesus monkeys.Surgery1975https://conductscience.org/library/papers/122797PubMed
2162,877Interaction of amino acids and cyclic AMP on the release of insulin and glucagon by newborn rat pancreas.Endocrinology1975https://conductscience.org/library/papers/162877PubMed
3237,936Identification of glucagon in the gastrointestinal tract.J Clin Invest1975https://conductscience.org/library/papers/237936PubMed
4808,435Transplantation of the islets of Langerhans and the histocompatibility of endocrine tissue.Diabetes1975https://conductscience.org/library/papers/808435PubMed
54,102,029Isolation of human pancreatic islets capable of releasing insulin and metabolising glucose in vitro.Lancet1971https://conductscience.org/library/papers/4102029PubMed
64,129,637In vitro studies of the rate of proinsulin and insulin turnover in seven human insulinomas.Eur J Clin Invest1973https://conductscience.org/library/papers/4129637PubMed
74,200,461Transplantation of isolated pancreatic islets into the portal vein of diabetic rats.Nature1973https://conductscience.org/library/papers/4200461PubMed
84,206,467Isolation of human and porcine islets of Langerhans and islet transplantation in pigs.J Surg Res1974https://conductscience.org/library/papers/4206467PubMed
94,211,886Conference on beta cell function, transplantation, and implantable glucose sensors: a summary.Metabolism1974https://conductscience.org/library/papers/4211886PubMed
104,216,091Physiologic and immunologic status of long-functioning transplanted pancreatic islets in rats.Surg Forum1974https://conductscience.org/library/papers/4216091PubMed
114,216,092Tissue culture of adult human islets of Langerhans for transplantation.Surg Forum1974https://conductscience.org/library/papers/4216092PubMed
124,260,606Oxidation of glucose and fatty acids in normal and in A 2 -cell rich pancreatic islets isolated from guinea-pigs.Diabetologia1972https://conductscience.org/library/papers/4260606PubMed
134,262,169Transplantation of intact pancreatic islets in rats.Surgery1972https://conductscience.org/library/papers/4262169PubMed
144,266,674Transplantation of isolated pancreatic islets across strong and weak histocompatibility barriers.Transplant Proc1973https://conductscience.org/library/papers/4266674PubMed
154,275,236Preliminary experience with pancreatic islet-cell implantation.Mayo Clin Proc1974https://conductscience.org/library/papers/4275236PubMed
164,309,607Studies on the secretion of pancreatic glucagon.Diabetes1969https://conductscience.org/library/papers/4309607PubMed
174,335,545The effect of mannoheptulose on glucose- and pyruvate-stimulated oxygen uptake in normal mouse pancreatic islets.Biochim Biophys Acta1971https://conductscience.org/library/papers/4335545PubMed
184,339,758Glucose metabolism of pancreatic islets isolated from neonatal rats.Horm Metab Res1972https://conductscience.org/library/papers/4339758PubMed
194,362,120Regulation of adenylate cyclase and cyclic-AMP dependent protein kinase activities in A2-cell rich guinea-pig islets of Langerhans.Horm Metab Res1974https://conductscience.org/library/papers/4362120PubMed
204,559,919Metabolic characteristics of isolated pancreatic islets in tissue culture.Diabetes1972https://conductscience.org/library/papers/4559919PubMed

See all 34 references

Cited by25

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 95 citations.

PMIDTitleJournalYearIn PapersSource
35,772,687Importance of multiple endocrine cell types in islet organoids for type 1 diabetes treatment.Transl Res2022https://conductscience.org/library/papers/35772687PubMed
31,767,174The challenge of correctly reporting hormones content and secretion in isolated human islets.Mol Metab2019https://conductscience.org/library/papers/31767174PubMed
28,662,368Integration of mesenchymal stem cells into islet cell spheroids improves long-term viability, but not islet function.Islets2017https://conductscience.org/library/papers/28662368PubMed
26,457,418Krüppel-Like Factor 4 Overexpression Initiates a Mesenchymal-to-Epithelial Transition and Redifferentiation of Human Pancreatic Cells following Expansion in Long Term Adherent Culture.PLoS One2015https://conductscience.org/library/papers/26457418PubMed
21,486,192Amyloid in the islets of Langerhans: thoughts and some historical aspects.Ups J Med Sci2011https://conductscience.org/library/papers/21486192PubMed
8,163,052Enzymatic, metabolic and secretory patterns in human islets of type 2 (non-insulin-dependent) diabetic patients.Diabetologia1994https://conductscience.org/library/papers/8163052PubMed
7,023,389Nesidioblastosis of the pancreas: definition of the syndrome and the management of the severe neonatal hyperinsulinaemic hypoglycaemia.Arch Dis Child1981https://conductscience.org/library/papers/7023389PubMed
6,998,814Insulin release from human pancreatic islets in vitro.Diabetologia1980https://conductscience.org/library/papers/6998814PubMed
6,994,885Organ culture of the Islets of Langerhans from young and senescent rats.Cell Tissue Res1980https://conductscience.org/library/papers/6994885PubMed
6,852,833Organ explant culture of adult Syrian golden hamster pancreas.In Vitro1983https://conductscience.org/library/papers/6852833PubMed
6,820,095Pancreas and islet transplantation.Jpn J Surg1982https://conductscience.org/library/papers/6820095PubMed
6,786,945Pancreas and islet transplantation. II. Clinical trials.Diabetologia1981https://conductscience.org/library/papers/6786945PubMed
6,293,963Cell culture and in vitro studies of fresh and cryopreserved human insulinoma.In Vitro1982https://conductscience.org/library/papers/6293963PubMed
6,166,539Glucagon production by cultured pancreatic islets: effects of different culture conditions and media.In Vitro1981https://conductscience.org/library/papers/6166539PubMed
3,897,182Insulin secretion from perifused rat pancreatic pseudoislets.In Vitro Cell Dev Biol1985https://conductscience.org/library/papers/3897182PubMed
3,884,420Properties of isolated human islets of Langerhans: insulin secretion, glucose oxidation and protein phosphorylation.Diabetologia1985https://conductscience.org/library/papers/3884420PubMed
2,894,388Studies on insulin secretion by monolayer cultures of normal and tumorous human pancreatic cells. Effects of glucose, somatostatin and SMS 201-995.J Endocrinol Invest1987https://conductscience.org/library/papers/2894388PubMed
2,210,121Regulation of insulin release in persistent hyperinsulinaemic hypoglycaemia of infancy studied in long-term culture of pancreatic tissue.Diabetologia1990https://conductscience.org/library/papers/2210121PubMed
2,075,782Islet isolation assessment in man and large animals.Acta Diabetol Lat1990https://conductscience.org/library/papers/2075782PubMed
405,802Pancreas and islet transplantation.World J Surg1977https://conductscience.org/library/papers/405802PubMed

See all 25 cited by

Genes2

The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.

GeneNCBI Gene IDLinked byIn GenesSource
GCG2,641PubTator's text mininghttps://conductscience.org/library/genes/2641NCBI Gene
INS3,630PubTator's text mininghttps://conductscience.org/library/genes/3630NCBI Gene

Data dates

The date of each source this release read.

PubMed
2026-11-06
PubMed
iCite
2026-11-05
iCite
PMC's ID file
2026-11-05
PMC's ID file
NIH RePORTER's grant and paper links
2026-11-01
NIH RePORTER's grant and paper links
Trials
2026-11-12
Gene search
2026-11-11
Pipelines
2026-09-18

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  • NCBI GenePublic domain (US government)
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  • Open TargetsCC0 1.0
  • PMC's ID filePublic domain (US government)
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • HGNCCC0: https://www.genenames.org/about/license/
  • iCiteCC BY 4.0
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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