Paper · 8970159

NG2 proteoglycan and the actin-binding protein fascin define separate populations of actin-containing filopodia and lamellipodia during cell spreading and migration.

Lin XH and 3 others. Mol Biol Cell, 1996. Cited by 37 papers, by iCite.

11 sourcespapers-2026-11-12-0.1.0

Cite this record

ConductScience Library. NG2 proteoglycan and the actin-binding protein fascin define separate populations of actin-containing filopodia and lamellipodia during cell spreading and migration. Papers, record 8970159. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/8970159

On this page

Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title: NG2 proteoglycan and the actin-binding protein fascin define separate populations of actin-containing filopodia and lamellipodia during cell spreading and migration.; PubMed
Journal: Mol Biol Cell; PubMed
Year: 1996; PubMed
Publication types: Journal Article, Research Support, U.S. Gov't, P.H.S.; PubMed
PubMed: https://pubmed.ncbi.nlm.nih.gov/8970159/; PubMed
DOI: https://doi.org/10.1091/mbc.7.12.1977; PubMed
PMC: https://pmc.ncbi.nlm.nih.gov/articles/PMC276044/; PubMed
The journal: https://conductscience.org/library/journal-index/9201390; PubMed
Citations, by iCite: 37; iCite
Relative citation ratio, by iCite: 0.7; iCite
Revised in PubMed: 2026-01-28; PubMed

Authors4

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

Order	Author	Forename
1	Lin XH	X H
2	Grako KA	K A
3	Burg MA	M A
4	Stallcup WB	W B

Source PubMed

Topics17

NLM's MeSH indexing of the paper, its major topics first.

MeSH term	Major
Actins	Major topic
Antigens	Major topic
Carrier Proteins	Major topic
Cell Movement	Major topic
Microfilament Proteins	Major topic
Proteoglycans	Major topic
Animals
Cell Compartmentation
Cell Membrane
Cytoskeleton
Fibronectins
Humans
Microscopy, Video
Polylysine
Rats
Tumor Cells, Cultured
Chondroitin Sulfate Proteoglycan 4

Source PubMed

Grants3

Each grant PubMed's record writes, matched to the NIH project NIH's grant and paper links name for this paper, and each of those links the record does not write.

Grant, as the record writes it	Agency	Country	NIH project	Stated by	Source
5 T32 CA09579	NCI NIH HHS	United States	T32CA009579	PubMed and NIH	NIH RePORTER
NS21990	NINDS NIH HHS	United States	R01NS021990	PubMed and NIH	NIH RePORTER
P01HD25938	NICHD NIH HHS	United States	P01HD025938	PubMed and NIH	NIH RePORTER

Trials0

The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.

None in this release.

Comments and corrections0

PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.

None in this release.

References33

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

Order	PMID	Title	Journal	Year	In Papers	Source
1	7,309,801	Surface changes during retraction-induced spreading of fibroblasts.	J Cell Sci	1981	https://conductscience.org/library/papers/7309801	PubMed
2	1,893,386	Correlation of chondroitin sulfate proteoglycan expression on proliferating brain capillary endothelial cells with the malignant phenotype of astroglial cells.	Cancer Res	1991	https://conductscience.org/library/papers/1893386	PubMed
3	6,576,184	Inhibition of anchorage-independent growth of human melanoma cells by a monoclonal antibody to a chondroitin sulfate proteoglycan.	J Natl Cancer Inst	1983	https://conductscience.org/library/papers/6576184	PubMed
4	2,942,306	Rationale and methods for the use of nude mice to study the biology and therapy of human cancer metastasis.	Cancer Metastasis Rev	1986	https://conductscience.org/library/papers/2942306	PubMed
5	3,525,578	Intracellular localization of the 55-kD actin-bundling protein in cultured cells: spatial relationships with actin, alpha-actinin, tropomyosin, and fimbrin.	J Cell Biol	1986	https://conductscience.org/library/papers/3525578	PubMed
6	2,443,508	Human osteosarcoma cells resistant to detachment by an Arg-Gly-Asp-containing peptide overproduce the fibronectin receptor.	J Cell Biol	1987	https://conductscience.org/library/papers/2443508	PubMed
7	2,963,010	Mouse T lymphoma cells contain a transmembrane glycoprotein (GP85) that binds ankyrin.	J Cell Biol	1988	https://conductscience.org/library/papers/2963010	PubMed
8	3,412,448	Neural adhesion molecule L1 as a member of the immunoglobulin superfamily with binding domains similar to fibronectin.	Nature	1988	https://conductscience.org/library/papers/3412448	PubMed
9	2,269,670	Interaction of the NG2 chondroitin sulfate proteoglycan with type VI collagen.	J Cell Biol	1990	https://conductscience.org/library/papers/2269670	PubMed
10	2,049,790	Cell locomotion: new research tests old ideas on membrane and cytoskeletal flow.	Cell Motil Cytoskeleton	1991	https://conductscience.org/library/papers/2049790	PubMed

1 to 10 of 33

See all 33 references

Cited by12

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 37 citations.

PMID	Title	Journal	Year	In Papers	Source
27,292,772	Functional roles of CSPG4/NG2 in chondrosarcoma.	Int J Exp Pathol	2016	https://conductscience.org/library/papers/27292772	PubMed
24,390,567	Transduction of extracellular cues into cell polarity: the role of the transmembrane proteoglycan NG2.	Mol Neurobiol	2014	https://conductscience.org/library/papers/24390567	PubMed
20,043,946	NG2 cells: Properties, progeny and origin.	Brain Res Rev	2010	https://conductscience.org/library/papers/20043946	PubMed
19,386,914	A novel function for p53: regulation of growth cone motility through interaction with Rho kinase.	J Neurosci	2009	https://conductscience.org/library/papers/19386914	PubMed
19,262,111	A role for the NG2 proteoglycan in glioma progression.	Cell Adh Migr	2008	https://conductscience.org/library/papers/19262111	PubMed
16,367,801	NG2-expressing cells in the nervous system: role of the proteoglycan in migration and glial-neuron interaction.	J Anat	2005	https://conductscience.org/library/papers/16367801	PubMed
10,967,549	The multi-PDZ domain protein MUPP1 is a cytoplasmic ligand for the membrane-spanning proteoglycan NG2.	J Cell Biochem	2000	https://conductscience.org/library/papers/10967549	PubMed
10,644,995	Replacing two conserved tyrosines of the EphB2 receptor with glutamic acid prevents binding of SH2 domains without abrogating kinase activity and biological responses.	Oncogene	2000	https://conductscience.org/library/papers/10644995	PubMed
10,512,873	Cytoskeletal reorganization induced by engagement of the NG2 proteoglycan leads to cell spreading and migration.	Mol Biol Cell	1999	https://conductscience.org/library/papers/10512873	PubMed
10,233,160	Fibronectin regulates assembly of actin filaments and focal contacts in cultured cells via the heparin-binding site in repeat III13.	Mol Biol Cell	1999	https://conductscience.org/library/papers/10233160	PubMed

1 to 10 of 12

See all 12 cited by

Genes4

The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.

Gene	NCBI Gene ID	Linked by	In Genes	Source
CSPG4	1,464	PubTator's text mining	https://conductscience.org/library/genes/1464	NCBI Gene
FN1	2,335	PubTator's text mining	https://conductscience.org/library/genes/2335	NCBI Gene
FSCN1	6,624	PubTator's text mining	https://conductscience.org/library/genes/6624	NCBI Gene
TNC	3,371	PubTator's text mining	https://conductscience.org/library/genes/3371	NCBI Gene

Drugs0

The drugs whose trials, in the Pipelines release, list the paper.

None in this release.

Data0

The data bank entries PubMed's record names. Trial numbers are under Trials.

None in this release.

Data dates

The date of each source this release read.

PubMed: 2026-11-06; PubMed
iCite: 2026-11-05; iCite
PMC's ID file: 2026-11-05; PMC's ID file
NIH RePORTER's grant and paper links: 2026-11-01; NIH RePORTER's grant and paper links
Trials: 2026-11-12
Gene search: 2026-11-11
Pipelines: 2026-09-18

Sources 11

ChEMBL, through Open TargetsCC BY-SA 3.0
ClinicalTrials.govNo license stated
HGNCCC0
iCiteCC BY 4.0
NCBI GenePublic domain (US government)
NIH RePORTER's grant and paper linksPublic domain
Open TargetsCC0 1.0
PMC's ID filePublic domain (US government)
PubMedNLM's terms
PubTator 3Public domain
UniProtCC BY 4.0

Each source's terms

ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
ClinicalTrials.govnone stated
HGNCCC0: https://www.genenames.org/about/license/
iCiteCC BY 4.0
NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
PubMedNLM's terms
PubTator 3Public domain
UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this paper from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/papers/v1/8970159

GET https://conductscience.org/api/papers/v1/8970159/references?page=2

API reference For AI assistants