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One gene with its proteins, patents, drugs, trials, grants and papers.
85,013 comparisons from ClinicalTrials.gov.
Most participants first33,758 with no events in either group come last2,581 to 2,600 of 85,013
| Comparison | With the outcome | Risk difference, 95% interval | Participants | Trial |
|---|---|---|---|---|
| Anastrozole vs Tamoxifen: serious adverse events | 333 of 1,449 371 of 1,489 | -1.9 points -5.0 to 1.2 | 2,938 | NCT00072462 Adjuvant Tamoxifen Compared With Anastrozole in Treating Postmenopausal Women With Ductal Carcinoma In Situ |
| Conceptrol vs Amphora: serious adverse events | 19 of 1,477 11 of 1,458 | 0.5 points -0.2 to 1.3 | 2,935 | NCT01306331 Study of Contraceptive Efficacy & Safety of Phexxi™ (Previously Known as Amphora) Gel Compared to Conceptrol Vaginal Gel |
| Standard RRT Initiation vs Accelerated RRT Initiation: All-cause Mortality. | 639 of 1,462 643 of 1,465 | -0.2 points -3.8 to 3.4 | 2,927 | NCT02568722 Standard vs. Accelerated Initiation of RRT in Acute Kidney Injury (STARRT-AKI: Principal Trial) |
| Standard RRT Initiation vs Accelerated RRT Initiation: deaths from any cause | 639 of 1,462 643 of 1,465 | -0.2 points -3.8 to 3.4 | 2,927 | NCT02568722 Standard vs. Accelerated Initiation of RRT in Acute Kidney Injury (STARRT-AKI: Principal Trial) |
| Contact Tracing Household-based Sub-arm vs Contact Tracing Incentive-based Sub-arm: Comparative Treatment Initiation Ratio in the Incentive-based Versus Household-based Contact Investigation Arms | 1,413 of 1,413 1,510 of 1,510 | 0.0 points -0.3 to 0.3 | 2,923 | NCT02808507 Comparative Effectiveness/Implementation of TB Case Finding in Rural South Africa |
| Contact Tracing Household-based Sub-arm vs Contact Tracing Incentive-based Sub-arm: Comparative Number of Secondary TB Cases Identified in Incentive-based Versus Household-based Contact Tracing | 17 of 1,413 17 of 1,510 | 0.1 points -0.7 to 0.9 | 2,923 | NCT02808507 Comparative Effectiveness/Implementation of TB Case Finding in Rural South Africa |
| Patient Self-Testing (PST) vs High Quality Anticoagulation Management (HQACM): serious adverse events | 247 of 1,465 250 of 1,457 | -0.3 points -3.0 to 2.4 | 2,922 | NCT00032591 The Home INR Study |
| Otilimab 90 mg vs Otilimab 150 mg: Number of Participants With Anti-GSK3196165 Antibodies | 11 of 1,456 10 of 1,459 | 0.1 points -0.6 to 0.7 | 2,915 | NCT04333147 Long-term Safety and Efficacy of GSK3196165 (Otilimab) in the Treatment of Rheumatoid Arthritis (RA) |
| Otilimab 90 mg vs Otilimab 150 mg: deaths from any cause | 10 of 1,456 9 of 1,459 | 0.1 points -0.6 to 0.7 | 2,915 | NCT04333147 Long-term Safety and Efficacy of GSK3196165 (Otilimab) in the Treatment of Rheumatoid Arthritis (RA) |
| Otilimab 90 mg vs Otilimab 150 mg: serious adverse events | 123 of 1,456 114 of 1,459 | 0.6 points -1.4 to 2.6 | 2,915 | NCT04333147 Long-term Safety and Efficacy of GSK3196165 (Otilimab) in the Treatment of Rheumatoid Arthritis (RA) |
| Acadesine vs Placebo (Normal Saline): serious adverse events | 327 of 1,442 329 of 1,457 | 0.1 points -2.9 to 3.1 | 2,899 | NCT00872001 The Effect Of Acadesine On Reducing Cardiovascular and Cerebrovascular Adverse Events In Coronary Artery Bypass Graft (CABG) Surgery (Study P05633 AM1)(TERMINATED) |
| Low-dose CT vs Standard-dose CT: Diagnostic Confidence in Diagnosing and Ruling Out Appendicitis: Indeterminate Interpretation (Grade 3) | 34 of 1,459 53 of 1,429 | -1.4 points -2.7 to -0.1 | 2,888 | NCT01925014 Low vs. Standard Dose CT for Appendicitis Trial |
| Palbociclib + Aromatase Inhibitor vs Aromatase Inhibitor: deaths from any cause | 420 of 1,324 736 of 1,564 | -15.3 points -18.8 to -11.8 | 2,888 | NCT05361655 Real-World Effectiveness of Palbociclib in Combination With an Aromatase Inhibitor |
| Liberal vs Restrictive: Acute Kidney Injury | 72 of 1,439 124 of 1,443 | -3.6 points -5.4 to -1.8 | 2,882 | NCT01424150 REstrictive Versus LIbEral Fluid Therapy in Major Abdominal Surgery: RELIEF Study |
| Tofacitinib 10 mg vs Tofacitinib 5 mg or 10 mg: Number of Participants With Malignancy Events | 87 of 2,281 26 of 586 | -0.6 points -2.7 to 1.0 | 2,867 | NCT01163253 A Long Term Study To Evaluate The Safety And Tolerability Of CP-690,550 For Patients With Moderate To Severe Chronic Plaque Psoriasis |
| Tofacitinib 10 mg vs Tofacitinib 5 mg or 10 mg: Number of Participants With Electrocardiogram (ECG) Abnormalities | 7 of 2,281 2 of 586 | -0.0 points -0.9 to 0.4 | 2,867 | NCT01163253 A Long Term Study To Evaluate The Safety And Tolerability Of CP-690,550 For Patients With Moderate To Severe Chronic Plaque Psoriasis |
| Tofacitinib 10 mg vs Tofacitinib 5 mg or 10 mg: Number of Participants With Adjudicated Cardiovascular Events | 32 of 2,281 13 of 586 | -0.8 points -2.4 to 0.3 | 2,867 | NCT01163253 A Long Term Study To Evaluate The Safety And Tolerability Of CP-690,550 For Patients With Moderate To Severe Chronic Plaque Psoriasis |
| Tofacitinib 10 mg vs Tofacitinib 5 mg or 10 mg: serious adverse events | 304 of 2,281 88 of 586 | -1.7 points -5.1 to 1.3 | 2,867 | NCT01163253 A Long Term Study To Evaluate The Safety And Tolerability Of CP-690,550 For Patients With Moderate To Severe Chronic Plaque Psoriasis |
| TICAGRELOR vs CLOPIDOGREL: Participants With Ventricular Pauses of Greater Than or Equal to 3 Seconds in Patients Monitored by Holter 24-hour ECG Recorders for 1 Week Following Randomization | 84 of 1,451 51 of 1,415 | 2.2 points 0.6 to 3.8 | 2,866 | NCT00391872 A Comparison of Ticagrelor (AZD6140) and Clopidogrel in Patients With Acute Coronary Syndrome |
| Torsemide vs Furosemide: All-cause Mortality or All-cause Hospitalization, as Measured by Follow-up Phone Call or NDI (for Death) | 149 of 1,431 157 of 1,428 | -0.6 points -2.9 to 1.7 | 2,859 | NCT03296813 TRANSFORM-HF: ToRsemide compArisoN With furoSemide FORManagement of Heart Failure |
Code
curl "https://conductscience.org/api/comparisons/v1?page=130"
Response
The first 2 of this page's 20 results. GET /api/comparisons/v1?page=130
{
"data": {
"total": 85013,
"results": [
{
"id": "NCT00072462-sae",
"title": "Anastrozole vs Tamoxifen: serious adverse events",
"summary": "333 of 1449 against 371 of 1489; risk difference -1.9 points, 95% interval -5.0 to 1.2; NCT00072462, Adjuvant Tamoxifen Compared With Anastrozole in Treating Postmenopausal Women With Ductal Carcinoma In Situ",
"record": "/library/comparisons/NCT00072462-sae",
"nct_id": "NCT00072462",
"kind": "serious-adverse-events",
"participants": 2938,
"risk_difference": {
"value": -0.01934684581339763,
"lower": -0.05014735273083506,
"upper": 0.011537631464459911
},
"group_1": "333 of 1,449",
"group_2": "371 of 1,489",
"difference": "-1.9 points",
"interval": "-5.0 to 1.2",
"trial_title": "Adjuvant Tamoxifen Compared With Anastrozole in Treating Postmenopausal Women With Ductal Carcinoma In Situ"
},
{
"id": "NCT01306331-sae",
"title": "Conceptrol vs Amphora: serious adverse events",
"summary": "19 of 1477 against 11 of 1458; risk difference 0.5 points, 95% interval -0.2 to 1.3; NCT01306331, Study of Contraceptive Efficacy & Safety of Phexxi™ (Previously Known as Amphora) Gel Compared to Conceptrol Vaginal Gel",
"record": "/library/comparisons/NCT01306331-sae",
"nct_id": "NCT01306331",
"kind": "serious-adverse-events",
"participants": 2935,
"risk_difference": {
"value": 0.005319331719191295,
"lower": -0.002181768420619348,
"upper": 0.013196788038202864
},
"group_1": "19 of 1,477",
"group_2": "11 of 1,458",
"difference": "0.5 points",
"interval": "-0.2 to 1.3",
"trial_title": "Study of Contraceptive Efficacy & Safety of Phexxi™ (Previously Known as Amphora) Gel Compared to Conceptrol Vaginal Gel"
}
],
"no_events": 33758,
"columns": [
{
"key": "title",
"label": "Comparison"
},
{
"key": "group_1",
"label": "With the outcome",
"under": "group_2"
},
{
"key": "difference",
"label": "Risk difference, 95% interval",
"under": "interval"
},
{
"key": "participants",
"label": "Participants"
},
{
"key": "nct_id",
"label": "Trial",
"under": "trial_title"
}
],
"order": "Most participants first",
"kinds": {
"all": 85013,
"outcome": 33568,
"serious-adverse-events": 31897,
"deaths": 19548
}
},
"release": "trial-comparisons-2026-03-23-0.1.0",
"terms": [
{
"source": "ClinicalTrials.gov's posted results, through CTTI's AACT",
"license": "ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299",
"notice": "ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.",
"short": "Freely available. Acknowledgement requested"
},
{
"source": "ClinicalTrials.gov",
"license": "none stated",
"notice": "ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.",
"short": "No license stated"
}
],
"next": "/api/comparisons/v1?page=131",
"request_id": "ZKAfLBVu_qLMvdr1"
}Ask about these results. The first 10 go in the prompt.
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.
NCBI Gene
One gene with its proteins, patents, drugs, trials, grants and papers.
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Search clinical trials by condition, drug, outcome or NCT number, with the results each one posted.
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For software
Every answer on this page is also JSON, under /api/comparisons/v1. No key.
GET https://conductscience.org/api/comparisons/v1?q=placebo%20heart%20failure&kind=outcome
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