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85,013 comparisons from ClinicalTrials.gov.

85,013 comparisons

Most participants first33,758 with no events in either group come last2,981 to 3,000 of 85,013

Show the results as
ComparisonWith the outcomeRisk difference, 95% intervalParticipantsTrial
TDF/FTC vs Placebo: Diagnosis of Gonorrhea During the Follow-up Period18 of 1,226

30 of 1,229

-1.0 points

-2.1 to 0.1

2,455NCT00458393

Emtricitabine/Tenofovir Disoproxil Fumarate for HIV Prevention in Men

TDF/FTC vs Placebo: Grade 2, 3, or 4 Laboratory Adverse Events70 of 1,229

79 of 1,226

-0.7 points

-2.7 to 1.2

2,455NCT00458393

Emtricitabine/Tenofovir Disoproxil Fumarate for HIV Prevention in Men

Absorb BVS vs XIENCE: Number of Participants With Repeat Coronary Arteriography140 of 1,218

161 of 1,237

-1.5 points

-4.1 to 1.1

2,455NCT02173379

Absorb IV Randomized Controlled Trial

TDF/FTC vs Placebo: Grade 3 or Higher Phosphorous Toxicity13 of 1,225

10 of 1,226

0.2 points

-0.6 to 1.1

2,451NCT00458393

Emtricitabine/Tenofovir Disoproxil Fumarate for HIV Prevention in Men

HEPLISAV and/or Placebo vs Engerix-B(1): serious adverse events78 of 1,968

23 of 481

-0.8 points

-3.2 to 1.0

2,449NCT01005407

Safety and Immunogenicity Study of the Hepatitis B Virus (HBV) Vaccine, HEPLISAV Compared to Engerix-B Vaccine

Folic Acid 4 mg vs Placebo: Need for Oxygen at 28 Days9 of 1,220

3 of 1,227

0.5 points

-0.1 to 1.2

2,447NCT01355159

High Dose Folic Acid Supplementation Throughout Pregnancy for Preeclampsia Prevention

Maraviroc Exposed vs Maraviroc Unexposed: deaths from any cause75 of 1,316

79 of 1,130

-1.3 points

-3.3 to 0.6

2,446NCT00665561

Prospective Observational Epidemiologic Study of Maraviroc's Safety

Maraviroc Exposed vs Maraviroc Unexposed: serious adverse events435 of 1,316

352 of 1,130

1.9 points

-1.8 to 5.6

2,446NCT00665561

Prospective Observational Epidemiologic Study of Maraviroc's Safety

Person-Centered Care vs Measurement-Based Care: deaths from any cause12 of 1,232

16 of 1,211

-0.3 points

-1.3 to 0.5

2,443NCT02507349

Person-Centered Versus Measurement-Based Care in Mental Health

TDF/FTC vs Placebo: HIV Seroconversion48 of 1,224

83 of 1,218

-2.9 points

-4.7 to -1.1

2,442NCT00458393

Emtricitabine/Tenofovir Disoproxil Fumarate for HIV Prevention in Men

Absorb BVS vs XIENCE: Number of Participants With Rehospitalization612 of 1,215

578 of 1,226

3.2 points

-0.7 to 7.2

2,441NCT02173379

Absorb IV Randomized Controlled Trial

GZR 100 mg + EBR 50 mg +/- RBV vs Other GZR Regimen: Number of Participants Who Experienced a Drug-Related Serious Adverse Event (SAE) During the Long-Term Follow-Up1 of 1,909

1 of 526

-0.1 points

-1.0 to 0.2

2,435NCT01667081

Durability of Virologic Response and/or Viral Resistance Patterns in Participants With Chronic Hepatitis C Who Have Been Previously Treated With Grazoprevir (MK-5172) (MK-5172-017)

GZR 100 mg + EBR 50 mg +/- RBV vs Other GZR Regimen: Number of Participants Who Experienced an Event of Clinical Interest (ECI) During the Long-Term Follow-Up98 of 1,909

4 of 526

4.4 points

2.9 to 5.6

2,435NCT01667081

Durability of Virologic Response and/or Viral Resistance Patterns in Participants With Chronic Hepatitis C Who Have Been Previously Treated With Grazoprevir (MK-5172) (MK-5172-017)

GZR 100 mg + EBR 50 mg +/- RBV vs Other GZR Regimen: Number of Participants Who Experienced a Drug-Related Adverse Event (AE) During the Long-Term Follow-Up1 of 1,909

1 of 526

-0.1 points

-1.0 to 0.2

2,435NCT01667081

Durability of Virologic Response and/or Viral Resistance Patterns in Participants With Chronic Hepatitis C Who Have Been Previously Treated With Grazoprevir (MK-5172) (MK-5172-017)

TDF/FTC vs Placebo: Grade 1 or Higher Creatinine Toxicity32 of 1,216

24 of 1,217

0.7 points

-0.6 to 1.9

2,433NCT00458393

Emtricitabine/Tenofovir Disoproxil Fumarate for HIV Prevention in Men

Stage 1 Participants vs Stage 2 Participants: Number of Participants Discontinued From Study Treatment Due to Adverse Events (Stage 1 and Stage 2)76 of 1,302

142 of 1,128

-6.8 points

-9.1 to -4.5

2,430NCT00724893

Efficacy of Pegetron® Redipen™ Treatment and Treatment Compliance of Patients With Chronic Hepatitis C in Canada (P04423)

Narrow Spectrum Antibiotic vs Broad-Spectrum Antibiotic: Sleep Disturbance582 of 1,570

378 of 860

-6.9 points

-11.0 to -2.8

2,430NCT02297815

Comparative Effectiveness of Antibiotics for Respiratory Infections

HEPLISAV and/or Placebo vs Engerix-B: serious adverse events28 of 1,821

13 of 607

-0.6 points

-2.2 to 0.5

2,428NCT00435812

Safety and Efficacy of HEPLISAV™ Hepatitis B Virus Vaccine Compared With Engerix-B® Vaccine

Video-based Intervention vs Usual Care: Number of Participants That Initiate an Osteoporosis Prescription Medication136 of 1,178

131 of 1,250

1.1 points

-1.4 to 3.6

2,428NCT01907269

A Direct-to-patient Intervention to Increase Rates of Osteoporosis Care

Absorb BVS vs XIENCE: Number of Participants Experienced Cardiac Death/All MI157 of 1,206

137 of 1,220

1.8 points

-0.8 to 4.4

2,426NCT02173379

Absorb IV Randomized Controlled Trial

Request

GET /api/comparisons/v1

Words from a trial's title, conditions or interventions, its outcome or its groups, or an NCT number.

An outcome counted in participants, the serious adverse events, or the deaths from any cause.

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Code

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curl "https://conductscience.org/api/comparisons/v1?page=150"

Response

The first 2 of this page's 20 results. GET /api/comparisons/v1?page=150

{
  "data": {
    "total": 85013,
    "results": [
      {
        "id": "NCT00458393-c1a51113",
        "title": "TDF/FTC vs Placebo: Diagnosis of Gonorrhea During the Follow-up Period",
        "summary": "18 of 1226 against 30 of 1229; risk difference -1.0 points, 95% interval -2.1 to 0.1; NCT00458393, Emtricitabine/Tenofovir Disoproxil Fumarate for HIV Prevention in Men",
        "record": "/library/comparisons/NCT00458393-c1a51113",
        "nct_id": "NCT00458393",
        "kind": "outcome",
        "participants": 2455,
        "risk_difference": {
          "value": -0.009728197170871955,
          "lower": -0.021277738182726318,
          "upper": 0.0013787387255951057
        },
        "group_1": "18 of 1,226",
        "group_2": "30 of 1,229",
        "difference": "-1.0 points",
        "interval": "-2.1 to 0.1",
        "trial_title": "Emtricitabine/Tenofovir Disoproxil Fumarate for HIV Prevention in Men"
      },
      {
        "id": "NCT00458393-cd1718e3",
        "title": "TDF/FTC vs Placebo: Grade 2, 3, or 4 Laboratory Adverse Events",
        "summary": "70 of 1229 against 79 of 1226; risk difference -0.7 points, 95% interval -2.7 to 1.2; NCT00458393, Emtricitabine/Tenofovir Disoproxil Fumarate for HIV Prevention in Men",
        "record": "/library/comparisons/NCT00458393-cd1718e3",
        "nct_id": "NCT00458393",
        "kind": "outcome",
        "participants": 2455,
        "risk_difference": {
          "value": -0.007480318618699536,
          "lower": -0.026579579117234742,
          "upper": 0.011534995110370382
        },
        "group_1": "70 of 1,229",
        "group_2": "79 of 1,226",
        "difference": "-0.7 points",
        "interval": "-2.7 to 1.2",
        "trial_title": "Emtricitabine/Tenofovir Disoproxil Fumarate for HIV Prevention in Men"
      }
    ],
    "no_events": 33758,
    "columns": [
      {
        "key": "title",
        "label": "Comparison"
      },
      {
        "key": "group_1",
        "label": "With the outcome",
        "under": "group_2"
      },
      {
        "key": "difference",
        "label": "Risk difference, 95% interval",
        "under": "interval"
      },
      {
        "key": "participants",
        "label": "Participants"
      },
      {
        "key": "nct_id",
        "label": "Trial",
        "under": "trial_title"
      }
    ],
    "order": "Most participants first",
    "kinds": {
      "all": 85013,
      "outcome": 33568,
      "serious-adverse-events": 31897,
      "deaths": 19548
    }
  },
  "release": "trial-comparisons-2026-03-23-0.1.0",
  "terms": [
    {
      "source": "ClinicalTrials.gov's posted results, through CTTI's AACT",
      "license": "ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299",
      "notice": "ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.",
      "short": "Freely available. Acknowledgement requested"
    },
    {
      "source": "ClinicalTrials.gov",
      "license": "none stated",
      "notice": "ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.",
      "short": "No license stated"
    }
  ],
  "next": "/api/comparisons/v1?page=151",
  "request_id": "gVpvaTOKaBasbWXo"
}

Ask about these results. The first 10 go in the prompt.

About this data
Holds
85,013 comparisons
From ClinicalTrials.gov. Counted 10 Nov 2026.
Release
23 Mar 2026
trial-comparisons-2026-03-23-0.1.0
Checked
20 of 20 review comparisons traced to ClinicalTrials.gov, and all 510,078 numbers calculated again apart from the builder agree
Access
Open
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Sources 2

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.

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Every answer on this page is also JSON, under /api/comparisons/v1. No key.

GET https://conductscience.org/api/comparisons/v1?q=placebo%20heart%20failure&kind=outcome

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