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85,013 comparisons from ClinicalTrials.gov. Counted 2026-11-10.
Most participants first33,758 with no events in either group come last301 to 320 of 85,013
| Comparison | With the outcome | Risk difference, 95% interval | Participants | Trial |
|---|---|---|---|---|
| Part A (Blinded): mRNA-1273 vs Part A (Blinded): Placebo: Part A: Number of Participants With a Secondary Case Definition of COVID-19 Starting 14 Days After Second Dose | 58 of 14,287 807 of 14,164 | -5.3 points -5.7 to -4.9 | 28,451 | NCT04470427 A Study to Evaluate Efficacy, Safety, and Immunogenicity of mRNA-1273 Vaccine in Adults Aged 18 Years and Older to Prevent COVID-19 |
| Part A (Blinded): mRNA-1273 vs Part A (Blinded): Placebo: Part A: Number of Participants With a First Occurrence of Either COVID-19 or SARS-CoV-2 Infection Regardless of Symptomatology or Severity Starting 14 Days After Second Dose | 280 of 14,287 1,339 of 14,164 | -7.5 points -8.0 to -7.0 | 28,451 | NCT04470427 A Study to Evaluate Efficacy, Safety, and Immunogenicity of mRNA-1273 Vaccine in Adults Aged 18 Years and Older to Prevent COVID-19 |
| COMIRNATY (Tozinameran) (1) If the Booster Vaccination Was Conducted, up to the Day Before Booster. vs COMIRNATY (Tozinameran) (2) If the Booster Vaccination Was Conducted, After the Booster.: deaths from any cause | 1 of 14,537 0 of 13,695 | 0.0 points -0.0 to 0.0 | 28,232 | NCT04815031 Drug Use Investigation of COMIRNATY Intramuscular Injection |
| COMIRNATY (Tozinameran) (1) If the Booster Vaccination Was Conducted, up to the Day Before Booster. vs COMIRNATY (Tozinameran) (2) If the Booster Vaccination Was Conducted, After the Booster.: serious adverse events | 120 of 14,537 48 of 13,695 | 0.5 points 0.3 to 0.7 | 28,232 | NCT04815031 Drug Use Investigation of COMIRNATY Intramuscular Injection |
| Double Blind Phase: Ad26.COV2.S vs Double Blind Phase: Placebo: Double Blind Phase: Number of Participants With First Occurrence of Molecularly Confirmed Moderate to Severe/Critical COVID-19 in Seronegative Participants With Onset at Least 1 Day After the First Day 1 Vaccination | 112 of 13,951 256 of 13,871 | -1.0 points -1.3 to -0.8 | 27,822 | NCT04614948 A Study of Ad26.COV2.S for the Prevention of SARS-CoV-2-mediated COVID-19 in Adults |
| Cases vs Controls (reference group): Risk of Depressive Episodes Within Adult Patients With Vitiligo | 157 of 6,206 501 of 21,602 | 0.2 points -0.2 to 0.7 | 27,808 | NCT04953338 Mental Health Associations With Vitiligo |
| AZD1222 vs Placebo: Number of Participants With First Symptomatic COVID-19 Regardless of Evidence of Prior SARS-CoV-2 Infection Post Second Dose of Study Intervention | 76 of 18,563 135 of 9,031 | -1.1 points -1.4 to -0.8 | 27,594 | NCT04516746 Phase III Double-blind, Placebo-controlled Study of AZD1222 for the Prevention of COVID-19 in Adults |
| Evolocumab vs Placebo: serious adverse events | 3,410 of 13,769 3,404 of 13,756 | 0.0 points -1.0 to 1.0 | 27,525 | NCT01764633 Further Cardiovascular Outcomes Research With PCSK9 Inhibition in Subjects With Elevated Risk |
| Iron and Folate vs Multiple Micronutrient: Post-neonatal Mortality | 139 of 13,517 115 of 13,748 | 0.2 points -0.0 to 0.4 | 27,265 | NCT00860470 Antenatal Micronutrient Supplementation and Infant Survival |
| Cases vs Controls (reference group): Risk of Recurrent Depressive Disorder Within Adult Patients With Vitilgo | 113 of 6,131 312 of 21,091 | 0.4 points 0.0 to 0.8 | 27,222 | NCT04953338 Mental Health Associations With Vitiligo |
| Iron and Folate vs Multiple Micronutrient: Very Pre-term | 385 of 13,333 291 of 13,475 | 0.7 points 0.4 to 1.1 | 26,808 | NCT00860470 Antenatal Micronutrient Supplementation and Infant Survival |
| Iron and Folate vs Multiple Micronutrient: Moderate to Late Preterm | 2,391 of 13,333 2,113 of 13,475 | 2.3 points 1.4 to 3.1 | 26,808 | NCT00860470 Antenatal Micronutrient Supplementation and Infant Survival |
| Iron and Folate vs Multiple Micronutrient: Preterm Birth | 2,912 of 13,333 2,510 of 13,475 | 3.2 points 2.3 to 4.2 | 26,808 | NCT00860470 Antenatal Micronutrient Supplementation and Infant Survival |
| Iron and Folate vs Multiple Micronutrient: Extremely Pre-term | 136 of 13,333 106 of 13,475 | 0.2 points 0.0 to 0.5 | 26,808 | NCT00860470 Antenatal Micronutrient Supplementation and Infant Survival |
| Empagliflozin - PS Balanced Cohort vs Liraglutide - PS Balanced Cohort: deaths from any cause | 881 of 14,148 765 of 12,626 | 0.2 points -0.4 to 0.7 | 26,774 | NCT03993132 A Study Using Medical Records of Danish People With Type 2 Diabetes Comparing Empagliflozin and Glucagon-Like Peptide-1 Receptor Agonists (GLP1-RA) in the Occurrence of Serious Cardiovascular Outcomes |
| Double Blind Phase: Ad26.COV2.S vs Double Blind Phase: Placebo: Double Blind Phase: Number of Participants With First Occurrence of Molecularly Confirmed Moderate to Severe/Critical COVID-19 With Onset at Least 14 Days After the First Day 1 Vaccination | 72 of 13,316 216 of 13,286 | -1.1 points -1.3 to -0.8 | 26,602 | NCT04614948 A Study of Ad26.COV2.S for the Prevention of SARS-CoV-2-mediated COVID-19 in Adults |
| Vorapaxar vs Placebo: serious adverse events | 3,514 of 13,186 3,419 of 13,166 | 0.7 points -0.4 to 1.7 | 26,352 | NCT00526474 Trial to Assess the Effects of Vorapaxar (SCH 530348; MK-5348) in Preventing Heart Attack and Stroke in Patients With Atherosclerosis (TRA 2°P - TIMI 50) (P04737) |
| AZD1222 vs Placebo: Number of Participants With Binary Response | 73 of 17,662 130 of 8,550 | -1.1 points -1.4 to -0.8 | 26,212 | NCT04516746 Phase III Double-blind, Placebo-controlled Study of AZD1222 for the Prevention of COVID-19 in Adults |
| AZD1222 vs Placebo: Number of Participants With First COVID-19 Symptomatic Illness Using University of Oxford-Defined Symptom Criteria Post Second Dose of Study Intervention | 86 of 17,662 136 of 8,550 | -1.1 points -1.4 to -0.8 | 26,212 | NCT04516746 Phase III Double-blind, Placebo-controlled Study of AZD1222 for the Prevention of COVID-19 in Adults |
| AZD1222 vs Placebo: Number of Participants With First COVID-19 Symptomatic Illness Using Centers for Disease Control and Prevention (CDC) Criteria Post Second Dose of Study Intervention | 95 of 17,662 145 of 8,550 | -1.2 points -1.5 to -0.9 | 26,212 | NCT04516746 Phase III Double-blind, Placebo-controlled Study of AZD1222 for the Prevention of COVID-19 in Adults |
Response
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"title": "Part A (Blinded): mRNA-1273 vs Part A (Blinded): Placebo: Part A: Number of Participants With a Secondary Case Definition of COVID-19 Starting 14 Days After Second Dose",
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Every answer on this page is also JSON, under /api/comparisons/v1. No key.
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