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85,013 comparisons from ClinicalTrials.gov. Counted 2026-11-10.

85,013 comparisons

Most participants first33,758 with no events in either group come last301 to 320 of 85,013

Show the results as
ComparisonWith the outcomeRisk difference, 95% intervalParticipantsTrial
Part A (Blinded): mRNA-1273 vs Part A (Blinded): Placebo: Part A: Number of Participants With a Secondary Case Definition of COVID-19 Starting 14 Days After Second Dose58 of 14,287

807 of 14,164

-5.3 points

-5.7 to -4.9

28,451NCT04470427

A Study to Evaluate Efficacy, Safety, and Immunogenicity of mRNA-1273 Vaccine in Adults Aged 18 Years and Older to Prevent COVID-19

Part A (Blinded): mRNA-1273 vs Part A (Blinded): Placebo: Part A: Number of Participants With a First Occurrence of Either COVID-19 or SARS-CoV-2 Infection Regardless of Symptomatology or Severity Starting 14 Days After Second Dose280 of 14,287

1,339 of 14,164

-7.5 points

-8.0 to -7.0

28,451NCT04470427

A Study to Evaluate Efficacy, Safety, and Immunogenicity of mRNA-1273 Vaccine in Adults Aged 18 Years and Older to Prevent COVID-19

COMIRNATY (Tozinameran) (1) If the Booster Vaccination Was Conducted, up to the Day Before Booster. vs COMIRNATY (Tozinameran) (2) If the Booster Vaccination Was Conducted, After the Booster.: deaths from any cause1 of 14,537

0 of 13,695

0.0 points

-0.0 to 0.0

28,232NCT04815031

Drug Use Investigation of COMIRNATY Intramuscular Injection

COMIRNATY (Tozinameran) (1) If the Booster Vaccination Was Conducted, up to the Day Before Booster. vs COMIRNATY (Tozinameran) (2) If the Booster Vaccination Was Conducted, After the Booster.: serious adverse events120 of 14,537

48 of 13,695

0.5 points

0.3 to 0.7

28,232NCT04815031

Drug Use Investigation of COMIRNATY Intramuscular Injection

Double Blind Phase: Ad26.COV2.S vs Double Blind Phase: Placebo: Double Blind Phase: Number of Participants With First Occurrence of Molecularly Confirmed Moderate to Severe/Critical COVID-19 in Seronegative Participants With Onset at Least 1 Day After the First Day 1 Vaccination112 of 13,951

256 of 13,871

-1.0 points

-1.3 to -0.8

27,822NCT04614948

A Study of Ad26.COV2.S for the Prevention of SARS-CoV-2-mediated COVID-19 in Adults

Cases vs Controls (reference group): Risk of Depressive Episodes Within Adult Patients With Vitiligo157 of 6,206

501 of 21,602

0.2 points

-0.2 to 0.7

27,808NCT04953338

Mental Health Associations With Vitiligo

AZD1222 vs Placebo: Number of Participants With First Symptomatic COVID-19 Regardless of Evidence of Prior SARS-CoV-2 Infection Post Second Dose of Study Intervention76 of 18,563

135 of 9,031

-1.1 points

-1.4 to -0.8

27,594NCT04516746

Phase III Double-blind, Placebo-controlled Study of AZD1222 for the Prevention of COVID-19 in Adults

Evolocumab vs Placebo: serious adverse events3,410 of 13,769

3,404 of 13,756

0.0 points

-1.0 to 1.0

27,525NCT01764633

Further Cardiovascular Outcomes Research With PCSK9 Inhibition in Subjects With Elevated Risk

Iron and Folate vs Multiple Micronutrient: Post-neonatal Mortality139 of 13,517

115 of 13,748

0.2 points

-0.0 to 0.4

27,265NCT00860470

Antenatal Micronutrient Supplementation and Infant Survival

Cases vs Controls (reference group): Risk of Recurrent Depressive Disorder Within Adult Patients With Vitilgo113 of 6,131

312 of 21,091

0.4 points

0.0 to 0.8

27,222NCT04953338

Mental Health Associations With Vitiligo

Iron and Folate vs Multiple Micronutrient: Very Pre-term385 of 13,333

291 of 13,475

0.7 points

0.4 to 1.1

26,808NCT00860470

Antenatal Micronutrient Supplementation and Infant Survival

Iron and Folate vs Multiple Micronutrient: Moderate to Late Preterm2,391 of 13,333

2,113 of 13,475

2.3 points

1.4 to 3.1

26,808NCT00860470

Antenatal Micronutrient Supplementation and Infant Survival

Iron and Folate vs Multiple Micronutrient: Preterm Birth2,912 of 13,333

2,510 of 13,475

3.2 points

2.3 to 4.2

26,808NCT00860470

Antenatal Micronutrient Supplementation and Infant Survival

Iron and Folate vs Multiple Micronutrient: Extremely Pre-term136 of 13,333

106 of 13,475

0.2 points

0.0 to 0.5

26,808NCT00860470

Antenatal Micronutrient Supplementation and Infant Survival

Empagliflozin - PS Balanced Cohort vs Liraglutide - PS Balanced Cohort: deaths from any cause881 of 14,148

765 of 12,626

0.2 points

-0.4 to 0.7

26,774NCT03993132

A Study Using Medical Records of Danish People With Type 2 Diabetes Comparing Empagliflozin and Glucagon-Like Peptide-1 Receptor Agonists (GLP1-RA) in the Occurrence of Serious Cardiovascular Outcomes

Double Blind Phase: Ad26.COV2.S vs Double Blind Phase: Placebo: Double Blind Phase: Number of Participants With First Occurrence of Molecularly Confirmed Moderate to Severe/Critical COVID-19 With Onset at Least 14 Days After the First Day 1 Vaccination72 of 13,316

216 of 13,286

-1.1 points

-1.3 to -0.8

26,602NCT04614948

A Study of Ad26.COV2.S for the Prevention of SARS-CoV-2-mediated COVID-19 in Adults

Vorapaxar vs Placebo: serious adverse events3,514 of 13,186

3,419 of 13,166

0.7 points

-0.4 to 1.7

26,352NCT00526474

Trial to Assess the Effects of Vorapaxar (SCH 530348; MK-5348) in Preventing Heart Attack and Stroke in Patients With Atherosclerosis (TRA 2°P - TIMI 50) (P04737)

AZD1222 vs Placebo: Number of Participants With Binary Response73 of 17,662

130 of 8,550

-1.1 points

-1.4 to -0.8

26,212NCT04516746

Phase III Double-blind, Placebo-controlled Study of AZD1222 for the Prevention of COVID-19 in Adults

AZD1222 vs Placebo: Number of Participants With First COVID-19 Symptomatic Illness Using University of Oxford-Defined Symptom Criteria Post Second Dose of Study Intervention86 of 17,662

136 of 8,550

-1.1 points

-1.4 to -0.8

26,212NCT04516746

Phase III Double-blind, Placebo-controlled Study of AZD1222 for the Prevention of COVID-19 in Adults

AZD1222 vs Placebo: Number of Participants With First COVID-19 Symptomatic Illness Using Centers for Disease Control and Prevention (CDC) Criteria Post Second Dose of Study Intervention95 of 17,662

145 of 8,550

-1.2 points

-1.5 to -0.9

26,212NCT04516746

Phase III Double-blind, Placebo-controlled Study of AZD1222 for the Prevention of COVID-19 in Adults

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Words from a trial's title, conditions or interventions, its outcome or its groups, or an NCT number.

An outcome counted in participants, the serious adverse events, or the deaths from any cause.

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The first 2 of this page's 20 results. GET /api/comparisons/v1?page=16

{
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      {
        "id": "NCT04470427-a19f9c16",
        "title": "Part A (Blinded): mRNA-1273 vs Part A (Blinded): Placebo: Part A: Number of Participants With a Secondary Case Definition of COVID-19 Starting 14 Days After Second Dose",
        "summary": "58 of 14287 against 807 of 14164; risk difference -5.3 points, 95% interval -5.7 to -4.9; NCT04470427, A Study to Evaluate Efficacy, Safety, and Immunogenicity of mRNA-1273 Vaccine in Adults Aged 18 Years and Older to Prevent COVID-19",
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        "title": "Part A (Blinded): mRNA-1273 vs Part A (Blinded): Placebo: Part A: Number of Participants With a First Occurrence of Either COVID-19 or SARS-CoV-2 Infection Regardless of Symptomatology or Severity Starting 14 Days After Second Dose",
        "summary": "280 of 14287 against 1339 of 14164; risk difference -7.5 points, 95% interval -8.0 to -7.0; NCT04470427, A Study to Evaluate Efficacy, Safety, and Immunogenicity of mRNA-1273 Vaccine in Adults Aged 18 Years and Older to Prevent COVID-19",
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trial-comparisons-2026-03-23-0.1.0Next page

Sources 2

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNone stated
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.

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