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85,013 comparisons from ClinicalTrials.gov.
Most participants first33,758 with no events in either group come last4,641 to 4,660 of 85,013
| Comparison | With the outcome | Risk difference, 95% interval | Participants | Trial |
|---|---|---|---|---|
| MAGE-A3 Group vs Placebo Group: Number of Subjects With Any Adverse Events (AEs) | 822 of 895 333 of 450 | 17.8 points 13.5 to 22.4 | 1,345 | NCT00796445 A Phase III Study to Test the Benefit of a New Kind of Anti-cancer Treatment in Patients With Melanoma, After Surgical Removal of Their Tumor |
| MAGE-A3 Group vs Placebo Group: deaths from any cause | 5 of 895 1 of 450 | 0.3 points -0.7 to 1.1 | 1,345 | NCT00796445 A Phase III Study to Test the Benefit of a New Kind of Anti-cancer Treatment in Patients With Melanoma, After Surgical Removal of Their Tumor |
| MAGE-A3 Group vs Placebo Group: serious adverse events | 129 of 895 64 of 450 | 0.2 points -3.9 to 4.0 | 1,345 | NCT00796445 A Phase III Study to Test the Benefit of a New Kind of Anti-cancer Treatment in Patients With Melanoma, After Surgical Removal of Their Tumor |
| Nadroparin vs Fondaparinux: serious adverse events | 9 of 670 6 of 674 | 0.5 points -0.8 to 1.7 | 1,344 | NCT00843492 A Study to Evaluate the Efficacy and Safety of Fondaparinux for the Prevention of Venous Blood Clots in Patients With a Plaster Cast or Other Type of Immobilization for a Below-knee Injury Not Needing Surgery |
| Rolapitant + Granisetron + Dexamethasone vs Placebo + Granisetron + Dexamethasone: serious adverse events | 89 of 670 103 of 674 | -2.0 points -5.7 to 1.8 | 1,344 | NCT01500226 Ph 3 Safety/Efficacy Study of Rolapitant for Prevention of CINV in Subjects Receiving Moderately Emetogenic Chemotherapy |
| Dabigatran vs Placebo: Centrally Confirmed Symptomatic Recurrent Deep Venous Thrombotic (DVT) Events During the Intended Treatment Period | 2 of 681 23 of 662 | -3.2 points -4.9 to -1.8 | 1,343 | NCT00558259 Twice-daily Oral Direct Thrombin Inhibitor Dabigatran Etexilate in the Long Term Prevention of Recurrent Symptomatic VTE |
| Dabigatran vs Placebo: Centrally Confirmed Unexplained Deaths During the Intended Treatment Period | 0 of 681 2 of 662 | -0.3 points -1.1 to 0.3 | 1,343 | NCT00558259 Twice-daily Oral Direct Thrombin Inhibitor Dabigatran Etexilate in the Long Term Prevention of Recurrent Symptomatic VTE |
| Dabigatran vs Placebo: Centrally Confirmed Cardiovascular Events During the Treatment Period | 3 of 684 2 of 659 | 0.1 points -0.7 to 1.0 | 1,343 | NCT00558259 Twice-daily Oral Direct Thrombin Inhibitor Dabigatran Etexilate in the Long Term Prevention of Recurrent Symptomatic VTE |
| Dabigatran vs Placebo: Centrally Confirmed Symptomatic Recurrent Venous Thrombotic Events (VTE) Including Unexplained Death During the Intended Treatment Period | 3 of 681 37 of 662 | -5.1 points -7.2 to -3.4 | 1,343 | NCT00558259 Twice-daily Oral Direct Thrombin Inhibitor Dabigatran Etexilate in the Long Term Prevention of Recurrent Symptomatic VTE |
| Dabigatran vs Placebo: Centrally Confirmed Symptomatic Recurrent Venous Thrombotic Events (VTE) Excluding Unexplained Death During the Intended Treatment Period | 3 of 681 35 of 662 | -4.8 points -6.8 to -3.2 | 1,343 | NCT00558259 Twice-daily Oral Direct Thrombin Inhibitor Dabigatran Etexilate in the Long Term Prevention of Recurrent Symptomatic VTE |
| Dabigatran vs Placebo: Centrally Confirmed Symptomatic Pulmonary Embolism (PE) Events During the Intended Treatment Period | 1 of 681 14 of 662 | -2.0 points -3.4 to -0.9 | 1,343 | NCT00558259 Twice-daily Oral Direct Thrombin Inhibitor Dabigatran Etexilate in the Long Term Prevention of Recurrent Symptomatic VTE |
| Dabigatran vs Placebo: serious adverse events | 47 of 684 60 of 659 | -2.2 points -5.2 to 0.7 | 1,343 | NCT00558259 Twice-daily Oral Direct Thrombin Inhibitor Dabigatran Etexilate in the Long Term Prevention of Recurrent Symptomatic VTE |
| Arm II (Selenium) vs Arm I (Placebo): serious adverse events | 13 of 865 9 of 477 | -0.4 points -2.2 to 1.0 | 1,342 | NCT00008385 Selenium in Preventing Tumor Growth in Patients With Previously Resected Stage I Non-small Cell Lung Cancer |
| Rimegepant 75 mg vs Placebo: serious adverse events | 1 of 668 2 of 674 | -0.1 points -0.9 to 0.6 | 1,342 | NCT04574362 Safety and Efficacy Trial of BHV3000 (Rimegepant) 75 mg for the Acute Treatment of Migraine |
| CHG Cloth vs Placebo Cloth: Number of Participants With Maternal Readmissions | 5 of 672 3 of 668 | 0.3 points -0.7 to 1.3 | 1,340 | NCT02402907 STRIPES Study: Study To Reduce Infection Post cEsarean Section |
| Antibiotics Therapy Arm vs Appendectomy Arm: Total Number of Patients Who Had Resolution of Appendicitis Symptoms at 30 Days | 462 of 676 466 of 663 | -1.9 points -6.9 to 3.0 | 1,339 | NCT02800785 The Comparison of Outcomes of Antibiotic Drugs and Appendectomy (CODA) Trial |
| High Dose Vitamin D Formulation vs Placebo: deaths from any cause | 159 of 681 137 of 656 | 2.5 points -2.0 to 6.9 | 1,337 | NCT03096314 Vitamin D to Improve Outcomes by Leveraging Early Treatment |
| Insulin Degludec (IDeg) vs Insulin Glargine (IGlar): serious adverse events | 64 of 671 65 of 665 | -0.2 points -3.4 to 3.0 | 1,336 | NCT02030600 A Trial Comparing the Safety and Efficacy of Insulin Degludec and Insulin Glargine, With or Without OADs in Subjects With Type 2 Diabetes |
| Hyperinsulinemic-normoglycemic Clamp vs Insulin at the Standard of Care Levels: All-cause Mortality | 32 of 653 22 of 682 | 1.7 points -0.5 to 3.9 | 1,335 | NCT00524472 Outcomes Study of Hyperinsulinemic Glucose Control in Cardiac Surgery |
| Orsiro Sirolimus Coronary Stent System vs Xience Everolimus Coronary Stent System: deaths from any cause | 56 of 884 27 of 450 | 0.3 points -2.6 to 2.9 | 1,334 | NCT02389946 Safety and Effectiveness of the Orsiro Sirolimus Eluting Coronary Stent System in Subjects With Coronary Artery Lesions |
Code
curl "https://conductscience.org/api/comparisons/v1?page=233"
Response
The first 2 of this page's 20 results. GET /api/comparisons/v1?page=233
{
"data": {
"total": 85013,
"results": [
{
"id": "NCT00796445-9e3268a9",
"title": "MAGE-A3 Group vs Placebo Group: Number of Subjects With Any Adverse Events (AEs)",
"summary": "822 of 895 against 333 of 450; risk difference 17.8 points, 95% interval 13.5 to 22.4; NCT00796445, A Phase III Study to Test the Benefit of a New Kind of Anti-cancer Treatment in Patients With Melanoma, After Surgical Removal of Their Tumor",
"record": "/library/comparisons/NCT00796445-9e3268a9",
"nct_id": "NCT00796445",
"kind": "outcome",
"participants": 1345,
"risk_difference": {
"value": 0.17843575418994417,
"lower": 0.13526759402201405,
"upper": 0.22385811663292526
},
"group_1": "822 of 895",
"group_2": "333 of 450",
"difference": "17.8 points",
"interval": "13.5 to 22.4",
"trial_title": "A Phase III Study to Test the Benefit of a New Kind of Anti-cancer Treatment in Patients With Melanoma, After Surgical Removal of Their Tumor"
},
{
"id": "NCT00796445-deaths",
"title": "MAGE-A3 Group vs Placebo Group: deaths from any cause",
"summary": "5 of 895 against 1 of 450; risk difference 0.3 points, 95% interval -0.7 to 1.1; NCT00796445, A Phase III Study to Test the Benefit of a New Kind of Anti-cancer Treatment in Patients With Melanoma, After Surgical Removal of Their Tumor",
"record": "/library/comparisons/NCT00796445-deaths",
"nct_id": "NCT00796445",
"kind": "deaths",
"participants": 1345,
"risk_difference": {
"value": 0.0033643699565487277,
"lower": -0.007379188087918093,
"upper": 0.01101062909852062
},
"group_1": "5 of 895",
"group_2": "1 of 450",
"difference": "0.3 points",
"interval": "-0.7 to 1.1",
"trial_title": "A Phase III Study to Test the Benefit of a New Kind of Anti-cancer Treatment in Patients With Melanoma, After Surgical Removal of Their Tumor"
}
],
"no_events": 33758,
"columns": [
{
"key": "title",
"label": "Comparison"
},
{
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"label": "With the outcome",
"under": "group_2"
},
{
"key": "difference",
"label": "Risk difference, 95% interval",
"under": "interval"
},
{
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},
{
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}
],
"order": "Most participants first",
"kinds": {
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"serious-adverse-events": 31897,
"deaths": 19548
}
},
"release": "trial-comparisons-2026-03-23-0.1.0",
"terms": [
{
"source": "ClinicalTrials.gov's posted results, through CTTI's AACT",
"license": "ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299",
"notice": "ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.",
"short": "Freely available. Acknowledgement requested"
},
{
"source": "ClinicalTrials.gov",
"license": "none stated",
"notice": "ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.",
"short": "No license stated"
}
],
"next": "/api/comparisons/v1?page=234",
"request_id": "8X6XQvzV-FPCjPgF"
}Ask about these results. The first 10 go in the prompt.
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.
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GET https://conductscience.org/api/comparisons/v1?q=placebo%20heart%20failure&kind=outcome
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