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85,013 comparisons from ClinicalTrials.gov.

85,013 comparisons

Most participants first33,758 with no events in either group come last4,921 to 4,940 of 85,013

Show the results as
ComparisonWith the outcomeRisk difference, 95% intervalParticipantsTrial
Lower Oxygen Saturation Target vs Higher Oxygen Saturation Target: Survival Without Severe Retinopathy of Prematurity (ROP) (Threshold Disease or the Need for Surgery)434 of 605

418 of 616

3.9 points

-1.3 to 9.0

1,221NCT00233324

Surfactant Positive Airway Pressure and Pulse Oximetry Trial

PARTICS vs Usual Care: deaths from any cause3 of 609

4 of 611

-0.2 points

-1.2 to 0.9

1,220NCT02995733

Patient Empowered Strategy to Reduce Asthma Morbidity in Highly Impacted Populations; PeRson EmPowered Asthma RElief

PARTICS vs Usual Care: serious adverse events75 of 609

74 of 611

0.2 points

-3.5 to 3.9

1,220NCT02995733

Patient Empowered Strategy to Reduce Asthma Morbidity in Highly Impacted Populations; PeRson EmPowered Asthma RElief

TDF-FTC, Condoms, Risk Counseling vs Placebo, Condoms, Risk Counseling: serious adverse events42 of 611

44 of 608

-0.4 points

-3.3 to 2.5

1,219NCT00448669

Botswana TDF/FTC Oral HIV Prophylaxis Trial

Symbicort pMDI vs Formoterol Turbuhaler: Number of Patients With Moderate or Severe COPD Exacerbation.171 of 606

204 of 613

-5.1 points

-10.2 to 0.1

1,219NCT02157935

Comparing the Efficacy of Symbicort® pMDI and Formoterol Turbuhaler in Reducing Exacerbations in Patients With Cronic Obstructive Pulmonary Disease

Formoterol 4.5 ug x2 Bid vs Symbicort 160/4.5 ug x2 Bid: serious adverse events63 of 613

49 of 605

2.2 points

-1.1 to 5.5

1,218NCT02157935

Comparing the Efficacy of Symbicort® pMDI and Formoterol Turbuhaler in Reducing Exacerbations in Patients With Cronic Obstructive Pulmonary Disease

Best Practice Clinic-Based Care vs Telehealth Care: Number of Participants Reporting Scheduling Visits as BP Care Burden at Six Months186 of 639

127 of 579

7.2 points

2.3 to 12.0

1,218NCT02996565

Pragmatic Trial Comparing Telehealth Care and Optimized Clinic-Based Care for Uncontrolled High Blood Pressure

Gefitinib vs Carboplatin/Paclitaxel: Objective Tumour Response Rate According to RECIST262 of 609

196 of 608

10.8 points

5.3 to 16.1

1,217NCT00322452

First Line IRESSA™ Versus Carboplatin/Paclitaxel in Asia

Apixaban vs Placebo: deaths from any cause12 of 610

9 of 607

0.5 points

-1.1 to 2.1

1,217NCT04650087

COVID-19 Thrombosis Prevention Trials: Post-hospital Thromboprophylaxis

Apixaban vs Placebo: serious adverse events71 of 610

66 of 607

0.8 points

-2.8 to 4.3

1,217NCT04650087

COVID-19 Thrombosis Prevention Trials: Post-hospital Thromboprophylaxis

Aflibercept/FOLFIRI vs Placebo/FOLFIRI: serious adverse events294 of 611

198 of 605

15.4 points

9.9 to 20.8

1,216NCT00561470

Aflibercept Versus Placebo in Combination With Irinotecan and 5-FU in the Treatment of Patients With Metastatic Colorectal Cancer After Failure of an Oxaliplatin Based Regimen

Tocilizumab vs TNF Inhibitor: Loss of Efficacy or Development of Intolerance to Biologic Therapy15 of 423

106 of 793

-9.8 points

-12.7 to -6.7

1,216NCT01543503

An Global Comparative Observational Study of RoActemra/Actemra (Tocilizumab) in Patients With Rheumatoid Arthritis

Tocilizumab vs TNF Inhibitor: serious adverse events22 of 423

64 of 793

-2.9 points

-5.6 to 0.2

1,216NCT01543503

An Global Comparative Observational Study of RoActemra/Actemra (Tocilizumab) in Patients With Rheumatoid Arthritis

Sotagliflozin vs Placebo: serious adverse events235 of 605

251 of 611

-2.2 points

-7.7 to 3.3

1,216NCT03521934

Effect of Sotagliflozin on Cardiovascular Events in Participants With Type 2 Diabetes Post Worsening Heart Failure (SOLOIST-WHF Trial)

PR5I vs INFANRIX Hexa: serious adverse events23 of 610

22 of 605

0.1 points

-2.1 to 2.3

1,215NCT01341639

Safety, Tolerability, and Immunogenicity of V419 in Healthy Infants When Given at 2, 3, 4 and 12 Months (V419-007)

Vismodegib - Locally Advanced vs Vismodegib - Metastatic: deaths from any cause103 of 1,119

19 of 96

-10.6 points

-19.8 to -3.6

1,215NCT01367665

STEVIE: A Study of Vismodegib in Patients With Locally Advanced or Metastatic Basal Cell Carcinoma

Vismodegib - Locally Advanced vs Vismodegib - Metastatic: serious adverse events272 of 1,119

31 of 96

-8.0 points

-18.2 to 0.9

1,215NCT01367665

STEVIE: A Study of Vismodegib in Patients With Locally Advanced or Metastatic Basal Cell Carcinoma

R092670 vs RISPERDAL CONSTA: serious adverse events41 of 606

29 of 608

2.0 points

-0.7 to 4.7

1,214NCT00589914

Comparison of Paliperidone Palmitate and RISPERDAL CONSTA in Patients With Schizophrenia

Academic Centers Population vs Community Centers Population: Training Evaluation - Freedom From DRSC in Academic and Community Hospitals428 of 430

781 of 784

-0.1 points

-1.3 to 0.7

1,214NCT02279888

CardioMEMS HF System Post Approval Study

Treatment vs Control: serious adverse events117 of 607

117 of 606

-0.0 points

-4.5 to 4.4

1,213NCT00545662

Study of Citicoline for the Treatment of Traumatic Brain Injury (COBRIT)

Request

GET /api/comparisons/v1

Words from a trial's title, conditions or interventions, its outcome or its groups, or an NCT number.

An outcome counted in participants, the serious adverse events, or the deaths from any cause.

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Code

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curl "https://conductscience.org/api/comparisons/v1?page=247"

Response

The first 2 of this page's 20 results. GET /api/comparisons/v1?page=247

{
  "data": {
    "total": 85013,
    "results": [
      {
        "id": "NCT00233324-14d6a3db",
        "title": "Lower Oxygen Saturation Target vs Higher Oxygen Saturation Target: Survival Without Severe Retinopathy of Prematurity (ROP) (Threshold Disease or the Need for Surgery)",
        "summary": "434 of 605 against 418 of 616; risk difference 3.9 points, 95% interval -1.3 to 9.0; NCT00233324, Surfactant Positive Airway Pressure and Pulse Oximetry Trial",
        "record": "/library/comparisons/NCT00233324-14d6a3db",
        "nct_id": "NCT00233324",
        "kind": "outcome",
        "participants": 1221,
        "risk_difference": {
          "value": 0.03878394332939783,
          "lower": -0.012733062960546222,
          "upper": 0.08997460416687708
        },
        "group_1": "434 of 605",
        "group_2": "418 of 616",
        "difference": "3.9 points",
        "interval": "-1.3 to 9.0",
        "trial_title": "Surfactant Positive Airway Pressure and Pulse Oximetry Trial"
      },
      {
        "id": "NCT02995733-deaths",
        "title": "PARTICS vs Usual Care: deaths from any cause",
        "summary": "3 of 609 against 4 of 611; risk difference -0.2 points, 95% interval -1.2 to 0.9; NCT02995733, Patient Empowered Strategy to Reduce Asthma Morbidity in Highly Impacted Populations; PeRson EmPowered Asthma RElief",
        "record": "/library/comparisons/NCT02995733-deaths",
        "nct_id": "NCT02995733",
        "kind": "deaths",
        "participants": 1220,
        "risk_difference": {
          "value": -0.0016205364701329487,
          "lower": -0.012291318163064351,
          "upper": 0.008645808382976282
        },
        "group_1": "3 of 609",
        "group_2": "4 of 611",
        "difference": "-0.2 points",
        "interval": "-1.2 to 0.9",
        "trial_title": "Patient Empowered Strategy to Reduce Asthma Morbidity in Highly Impacted Populations; PeRson EmPowered Asthma RElief"
      }
    ],
    "no_events": 33758,
    "columns": [
      {
        "key": "title",
        "label": "Comparison"
      },
      {
        "key": "group_1",
        "label": "With the outcome",
        "under": "group_2"
      },
      {
        "key": "difference",
        "label": "Risk difference, 95% interval",
        "under": "interval"
      },
      {
        "key": "participants",
        "label": "Participants"
      },
      {
        "key": "nct_id",
        "label": "Trial",
        "under": "trial_title"
      }
    ],
    "order": "Most participants first",
    "kinds": {
      "all": 85013,
      "outcome": 33568,
      "serious-adverse-events": 31897,
      "deaths": 19548
    }
  },
  "release": "trial-comparisons-2026-03-23-0.1.0",
  "terms": [
    {
      "source": "ClinicalTrials.gov's posted results, through CTTI's AACT",
      "license": "ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299",
      "notice": "ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.",
      "short": "Freely available. Acknowledgement requested"
    },
    {
      "source": "ClinicalTrials.gov",
      "license": "none stated",
      "notice": "ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.",
      "short": "No license stated"
    }
  ],
  "next": "/api/comparisons/v1?page=248",
  "request_id": "S1M0RW2TAYH1dF75"
}

Ask about these results. The first 10 go in the prompt.

About this data
Holds
85,013 comparisons
From ClinicalTrials.gov. Counted 10 Nov 2026.
Release
23 Mar 2026
trial-comparisons-2026-03-23-0.1.0
Checked
20 of 20 review comparisons traced to ClinicalTrials.gov, and all 510,078 numbers calculated again apart from the builder agree
Access
Open
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Sources 2

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.

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