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Disease · MONDO_0008538

Comparisons in its trials13

Comparisons Trial comparisons calculated in the trials shown here, most participants first. A comparison in one of these trials does not always compare a treatment for the disease, so read the two groups.

ComparisonGroup 1, with the outcomeGroup 2, with the outcomeParticipantsTrialSource
Mavrilimumab vs Placebo: deaths from any cause0 of 420 of 2870NCT03827018Trial comparisons
Mavrilimumab vs Placebo: serious adverse events2 of 423 of 2870NCT03827018Trial comparisons
Main Study: Guselkumab vs Main Study: Placebo: Main Study: Number of Participants With Treatment-emergent Serious Adverse Event (SAEs)6 of 350 of 1853NCT04633447Trial comparisons
Main Study: Guselkumab vs Main Study: Placebo: Main Study: Number of Participants With Treatment-emergent Adverse Events (TEAEs)34 of 3517 of 1853NCT04633447Trial comparisons
Secukinumab vs Placebo: Percentage of Participants With GCA Who Had Sustained Remission Until Week 5216 of 272 of 2552NCT03765788Trial comparisons
Secukinumab vs Placebo: Percentage of Participants in Remission at Week 1222 of 2712 of 2552NCT03765788Trial comparisons
Secukinumab vs Placebo: Percentage of Participants in Sustained Remission Until Week 2819 of 276 of 2552NCT03765788Trial comparisons
TCZ IV 7 mg/kg Q4W vs TCZ IV 6 mg/kg Q4W: deaths from any cause0 of 240 of 2246NCT03923738Trial comparisons
TCZ IV 7 mg/kg Q4W vs TCZ IV 6 mg/kg Q4W: serious adverse events3 of 241 of 2246NCT03923738Trial comparisons
Tocilizumab vs Placebo: Number of Relapse Free Patients17 of 202 of 1030NCT01450137Trial comparisons
Tocilizumab vs Placebo: Number of Patients That Have Achieved Complete Remission of Disease17 of 204 of 1030NCT01450137Trial comparisons
Tocilizumab vs Placebo: deaths from any cause0 of 201 of 1030NCT01450137Trial comparisons
Tocilizumab vs Placebo: serious adverse events7 of 205 of 1030NCT01450137Trial comparisons

diseases-2026-09-18-0.1.0

Sources 6

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • NLM's MeSHNLM's terms
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • NLM's MeSHNLM's
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this list from software.

Twenty rows a page, as JSON. No key.

GET https://conductscience.org/api/diseases/v1/MONDO_0008538/comparisons