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Drug · CHEMBL112

Comparisons in its trials404

Comparisons Trial comparisons calculated in the trials whose record names the drug, most participants first. A comparison in one of its trials does not always compare the drug, so read the two groups.

1 to 20 of 404

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ComparisonGroup 1, with the outcomeGroup 2, with the outcomeParticipantsTrialSource
Non-Opioid vs Opioid: Number of Participants Receiving Rescue Medication26 of 90954 of 9061,815NCT04452344Trial comparisons
Non-Opioid vs Opioid: deaths from any cause0 of 9090 of 9061,815NCT04452344Trial comparisons
Non-Opioid vs Opioid: serious adverse events1 of 9092 of 9061,815NCT04452344Trial comparisons
Original MMPR - Descending Dose Arm vs MAST MMPR - Escalating Dose Arm: Number of Participants Discharged From the Hospital With an Opioid Prescription527 of 787476 of 7741,561NCT03472469Trial comparisons
Original MMPR - Descending Dose Arm vs MAST MMPR - Escalating Dose Arm: deaths from any cause29 of 78736 of 7741,561NCT03472469Trial comparisons
Original MMPR - Descending Dose Arm vs MAST MMPR - Escalating Dose Arm: serious adverse events29 of 78736 of 7741,561NCT03472469Trial comparisons
Alternate Management vs Control: deaths from any cause0 of 4750 of 6411,116NCT03330119Trial comparisons
Alternate Management vs Control: serious adverse events0 of 4750 of 6411,116NCT03330119Trial comparisons
Acetaminophen 250 mg and Aspirin 250 mg vs Placebo: Number of Subjects Who Are Pain Free at the 2-hour Assessment90 of 40869 of 415823NCT01973205Trial comparisons
Acetaminophen 250 mg and Aspirin 250 mg vs Placebo: serious adverse events1 of 4080 of 415823NCT01973205Trial comparisons
Acetaminophen 250 mg and Aspirin 250 mg vs Placebo: Number of Subjects Who Are Free of Phonophobia at the 2-hour Assessment.164 of 403142 of 411814NCT01973205Trial comparisons
Acetaminophen 250 mg and Aspirin 250 mg vs Placebo: Number of Subjects Who Are Free of Photophobia at the 2-hour Assessment.127 of 403116 of 411814NCT01973205Trial comparisons
Acetaminophen 250 mg and Aspirin 250 mg vs Placebo: Number of Subjects Who Are Nausea Free at the 2-hour Assessment244 of 403208 of 411814NCT01973205Trial comparisons
Intravenous Acetaminophen vs Intravenous 0.9% Sodium Chloride: deaths from any cause0 of 2830 of 287570NCT02156154Trial comparisons
Intravenous Acetaminophen vs Intravenous 0.9% Sodium Chloride: serious adverse events0 of 2830 of 287570NCT02156154Trial comparisons
Intravenous Acetaminophen vs Intravenous 0.9% Sodium Chloride: Incidence of Postoperative Nausea and Vomiting140 of 280124 of 280560NCT02156154Trial comparisons
Oral Acetaminophen vs IV Acetaminophen: deaths from any cause0 of 2410 of 245486NCT02244619Trial comparisons
Oral Acetaminophen vs IV Acetaminophen: serious adverse events0 of 2410 of 245486NCT02244619Trial comparisons
Tramadol/Paracetamol (APAP) vs Non-Tramadol/APAP: serious adverse events1 of 2421 of 231473NCT01728246Trial comparisons
ACE ER 1500 mg vs Placebo: serious adverse events0 of 2680 of 134402NCT01960114Trial comparisons

pipelines-2026-09-18-0.3.1

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Sources 7

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ConductCognition's list of its testsOur own data
  • ClinicalTrials.govNo license stated
  • NLM's MeSHNLM's terms
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ConductCognition's list of its testsOur own data: ConductCognition's list of its tests, https://conductcognition.com
  • ClinicalTrials.govnone stated
  • NLM's MeSHNLM's
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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