Drug · CHEMBL688

FENTANYL CITRATE

7 sourcespipelines-2026-09-18-0.3.1

Cite this record

ConductScience Library. FENTANYL CITRATE. Drugs and targets, record CHEMBL688. Release pipelines-2026-09-18-0.3.1, 18 Sept 2026. https://conductscience.org/library/drugs/CHEMBL688

On this page

Drug

Names and IDs as ChEMBL gives them, through Open Targets.

Name: FENTANYL CITRATE; ChEMBL
ChEMBL ID: CHEMBL688; ChEMBL
Type: Small molecule; ChEMBL
Brand names: Abstral, Actiq, Effentora, Fentanyl citrate component of innovar, Fentanyl citrate preservative free, Fentora, Instanyl, Lazanda, Onsolis, Pecfent, Sublimaze, Sublimaze preservative free, Thalamonal; ChEMBL
Other names: Fentanyl buccal, Fentanyl citrate cii, Instanyl, Kw-2246, Leptanal, MCN-JR-4263-49, R-4263; ChEMBL
Parent form: FENTANYL, CHEMBL596; Drugs and targets
InChIKey: IVLVTNPOHDFFCJ-UHFFFAOYSA-N; ChEMBL
Open Targets' highest stage: Approval, for 4 of its 8 diseases, from DailyMed and PMDA; Open Targets

Targets1

The targets ChEMBL's mechanism records give for the drug, through Open Targets. A mechanism record says what the drug acts on, not how strongly.

Target	Protein	Mechanism	Action	Gene in Genes
OPRM1	Mu-type opioid receptor	Mu opioid receptor agonist	AGONIST	https://conductscience.org/library/genes/4988

Source ChEMBL

Diseases8

The diseases Open Targets' clinical reports study the drug for, the most trial reports first. The stage is Open Targets', the highest any of its sources reports for the pair, and each row names the sources that report it.

Disease	Open Targets' stage	Stage reported by	Reports	Of them trials	Its drugs
Pain	Approval	DailyMed and PMDA	20	6	https://conductscience.org/library/drugs?q=HP_0012531
cancer pain	Phase 2	ClinicalTrials.gov	1	1	https://conductscience.org/library/drugs?q=EFO_0801084
colon carcinoma	Phase 2	ClinicalTrials.gov	1	1	https://conductscience.org/library/drugs?q=MONDO_0002032
interstitial lung disease	Phase 3	ClinicalTrials.gov	1	1	https://conductscience.org/library/drugs?q=MONDO_0015925
malignant colon neoplasm	Phase 2	ClinicalTrials.gov	1	1	https://conductscience.org/library/drugs?q=MONDO_0021063
cancer	Approval	DailyMed and PMDA	4	0	https://conductscience.org/library/drugs?q=MONDO_0004992
Chronic pain	Approval	PMDA	1	0	https://conductscience.org/library/drugs?q=HP_0012532
migraine disorder	Approval	DailyMed	1	0	https://conductscience.org/library/drugs?q=MONDO_0005277

Source Open Targets

Trials40

Trials whose record names the drug by a name ChEMBL states, posted results first, then the largest. Open Targets read each trial's text to find its drugs.

Trial	Title	Phase	Participants	Results first posted	Named as	Linked by	Source
NCT02531971	Fentanyl Patch Pharmacokinetics in Healthy Adults	Phase 4	24	2020-03-26	fentanyl citrate	Its name	ClinicalTrials.gov
NCT05437575	Prehospital Analgesia INtervention Trial (PAIN)	Phase 3	994		fentanyl citrate	Its name	ClinicalTrials.gov
NCT00105937	OraVescent Fentanyl (OVF) for the Treatment of Breakthrough Pain in Opioid Tolerant Cancer Patients	Phase 3	300		fentanyl citrate	Its name	ClinicalTrials.gov
NCT00589823	Efficacy and Safety Study of Nasalfent for Treatment of Breakthrough Cancer Pain in Patients Taking Regular Opioids	Phase 3	135		fentanyl citrate	Its name	ClinicalTrials.gov
NCT03973957	Talc Outpatient Pleurodesis With Indwelling Catheter		124		fentanyl citrate	Its name	ClinicalTrials.gov
NCT00214955	Study to Evaluate the Efficacy and Safety of ORAVESCENT Fentanyl Citrate for the Management of Breakthrough Pain	Phase 3	120		fentanyl citrate	Its name	ClinicalTrials.gov
NCT00343733	Study to Evaluate the Efficacy and Safety of OraVescent Fentanyl Citrate Treatment for the Management of Breakthrough Pain in Opioid-Tolerant Patients With Noncancer-Related Chronic Pain	Phase 3	120		fentanyl citrate	Its name	ClinicalTrials.gov
NCT00105287	Treatment of Breakthrough Pain in Opioid Tolerant Cancer Patients	Phase 3	100		fentanyl citrate	Its name	ClinicalTrials.gov
NCT05861791	Comparison of Patient-controlled Analgesia Regimenfor Postoperative Pain in Patients Undergoing Total Knee Arthroplasty		98		fentanyl citrate	Its name	ClinicalTrials.gov
NCT02641340	Fentanyl Sublingual Spray in Opioid Naive Participants	Phase 1	96		fentanyl citrate	Its name	ClinicalTrials.gov

1 to 10 of 40

See all 40 trials

Comparisons in its trials0

Comparisons Trial comparisons calculated in the trials whose record names the drug, most participants first. A comparison in one of its trials does not always compare the drug, so read the two groups.

None in this release.

Papers from its trials14

The papers the trials whose record names the drug list on ClinicalTrials.gov as their results (RESULT) or as drawn from them (DERIVED), results first, newest first.

PMID	Listed as	Trials listing it	Source
24385406	RESULT	1	PubMed
23380337	RESULT	1	PubMed
21215653	RESULT	1	PubMed
19508134	RESULT	1	PubMed
18258412	RESULT	1	PubMed
10353500	RESULT	1	PubMed
37170709	DERIVED	1	PubMed
30662387	DERIVED	1	PubMed
29909433	DERIVED	1	PubMed
28942715	DERIVED	1	PubMed

1 to 10 of 14

See all 14 papers from its trials

Tests in its trials0

The tests ConductCognition runs that the trials whose record names the drug name in their registered outcomes, as ScienceGraph matched them. ConductCognition's list names the tests it runs, not every test a trial used.

None in this release.

Data dates

The date of each source this release read.

Open Targets: 2026-09-18; Open Targets
ClinicalTrials.gov: 2026-11-05; ClinicalTrials.gov
Results, from AACT: 2026-03-23; AACT
Papers the trials list, from Trials: 2026-11-12; Trials
Comparisons, from Trial comparisons: 2026-03-23; Trial comparisons
Tests named in the trials, as ScienceGraph matched them: 2026-11-12; ConductCognition

Sources 7

ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
ChEMBL, through Open TargetsCC BY-SA 3.0
ConductCognition's list of its testsOur own data
ClinicalTrials.govNo license stated
NLM's MeSHNLM's terms
Open TargetsCC0 1.0
PubMedNLM's terms

Each source's terms

ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
ConductCognition's list of its testsOur own data: ConductCognition's list of its tests, https://conductcognition.com
ClinicalTrials.govnone stated
NLM's MeSHNLM's
Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
PubMedNLM's terms

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this drug from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/drugs/v1/CHEMBL688

GET https://conductscience.org/api/drugs/v1/CHEMBL688/trials?page=2

API reference For AI assistants