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Drug · CHEMBL702

PIPERACILLIN

7 sourcespipelines-2026-09-18-0.3.1

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ConductScience Library. PIPERACILLIN. Drugs and targets, record CHEMBL702. Release pipelines-2026-09-18-0.3.1, 18 Sept 2026. https://conductscience.org/library/drugs/CHEMBL702

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Drug

Names and IDs as ChEMBL gives them, through Open Targets.

Name
PIPERACILLIN
ChEMBL
ChEMBL ID
CHEMBL702
ChEMBL
Type
Small molecule
ChEMBL
Other names
Peracin, Piperacilina, Piperacillin anhydrous, Piperacillin hydrate, Piperacillin monohydrate, Piperacillin, anhydrous, Piperacilline
ChEMBL
Other form
PIPERACILLIN SODIUM, CHEMBL1200820
Drugs and targets
DrugBank
DB00319
DrugBank
InChIKey
IVBHGBMCVLDMKU-GXNBUGAJSA-N
ChEMBL
Open Targets' highest stage
Approval, for 5 of its 33 diseases, from ATC, PMDA and TTD
Open Targets

Targets0

The targets ChEMBL's mechanism records give for the drug, through Open Targets. A mechanism record says what the drug acts on, not how strongly.

None in this release.

Diseases33

The diseases Open Targets' clinical reports study the drug for, the most trial reports first. The stage is Open Targets', the highest any of its sources reports for the pair, and each row names the sources that report it.

DiseaseOpen Targets' stageStage reported byReportsOf them trialsIts drugs
SepsisApprovalPMDA1211https://conductscience.org/library/drugs?q=HP_0100806
infectionPhase 3ClinicalTrials.gov99https://conductscience.org/library/drugs?q=EFO_0000544
bacterial infectious diseaseApprovalATC and TTD74https://conductscience.org/library/drugs?q=MONDO_0005113
appendicitisPhase 2ClinicalTrials.gov44https://conductscience.org/library/drugs?q=MONDO_0005649
septic shockPhase 3ClinicalTrials.gov44https://conductscience.org/library/drugs?q=EFO_0006834
pneumoniaApprovalPMDA32https://conductscience.org/library/drugs?q=MONDO_0005249
FeverUnknownClinicalTrials.gov22https://conductscience.org/library/drugs?q=HP_0001945
acute pyelonephritisPhase 3ClinicalTrials.gov22https://conductscience.org/library/drugs?q=MONDO_0003529
bacterial infectious disease with sepsisPhase 3ClinicalTrials.gov22https://conductscience.org/library/drugs?q=MONDO_0005229
neutropeniaUnknownClinicalTrials.gov22https://conductscience.org/library/drugs?q=MONDO_0001475

Trials122

Trials whose record names the drug by a name ChEMBL states, posted results first, then the largest. Open Targets read each trial's text to find its drugs. 1 more that Open Targets linked to it is not shown, since the release's checks do not confirm it.

TrialTitlePhaseParticipantsResults first postedNamed asLinked bySource
NCT05094154Effect of Antibiotic Choice On ReNal Outcomes (ACORN)Phase 42,6342023-12-22piperacillinIts nameClinicalTrials.gov
NCT03269994Does Cefoxitin or Piperacillin-Tazobactam Prevent Postoperative Surgical Site Infections After Pancreatoduodenectomy?Phase 39672025-10-21piperacillin-tazobactamA combination that names itClinicalTrials.gov
NCT01370616Ertapenem Sodium (MK-0826) Versus Piperacillin/Tazobactam Sodium for the Treatment of Diabetic Foot Infections in Chinese Adults (MK-0826-061)Phase 35652014-12-02piperacillinIts nameClinicalTrials.gov
NCT02753946Safety and Efficacy of ZTI-01 (IV Fosfomycin) vs Piperacillin/Tazobactam for Treatment cUTI/AP InfectionsPhase 2/34652018-12-11piperacillinIts nameClinicalTrials.gov
NCT03019965Efficacy of Betalactam Antibiotics in Prolonged Infusion Compared to Intermittent in Pediatric Patients With Sepsis4262021-08-05piperacillin/tazobactamA combination that names itClinicalTrials.gov
NCT01994993Antibiotic Safety (SCAMP)Phase 2/32602018-02-27piperacillin-tazobactamA combination that names itClinicalTrials.gov
NCT03289351Two Different Antibiotics Versus One Antibiotic for Pediatric Perforated AppendicitisPhase 41622024-01-12piperacillinIts nameClinicalTrials.gov
NCT03159754Optimal Care of Complicated AppendicitisPhase 4402023-11-28piperacillin-tazobactamA combination that names itClinicalTrials.gov
NCT02991937Comparison of Medical and Surgical Treatment of Uncomplicated Acute Appendicitis in ChildrenPhase 4392022-01-21piperacillin/tazobactamA combination that names itClinicalTrials.gov
NCT05102162BL Infusion Trial:Beta-lactam Continuous Versus Intermittent Infusion and Associated Bacterial Resistance and Therapy Outcomes in Critically Ill Patients With Severe PneumoniaPhase 4352023-12-12piperacillin/tazobactamA combination that names itClinicalTrials.gov

1 to 10 of 122

See all 122 trials

Comparisons in its trials33

Comparisons Trial comparisons calculated in the trials whose record names the drug, most participants first. A comparison in one of its trials does not always compare the drug, so read the two groups.

ComparisonGroup 1, with the outcomeGroup 2, with the outcomeParticipantsTrialSource
Anti-pseudomonal Cephalosporin vs Anti-pseudomonal Penicillin: Major Adverse Kidney Events Within 14 Days (MAKE14)124 of 1,214114 of 1,2972,511NCT05094154Trial comparisons
Anti-pseudomonal Cephalosporin vs Anti-pseudomonal Penicillin: deaths from any cause104 of 1,214106 of 1,2972,511NCT05094154Trial comparisons
Anti-pseudomonal Cephalosporin vs Anti-pseudomonal Penicillin: serious adverse events0 of 1,2140 of 1,2972,511NCT05094154Trial comparisons
Cefoxitin vs Piperacillin-tazobactam: Number of Participants Evaluated for the Effectiveness of Cefoxitin as a Surgical Antibiotic Prophylaxis.400 of 400378 of 378778NCT03269994Trial comparisons
Cefoxitin vs Piperacillin-tazobactam: deaths from any cause10 of 4005 of 378778NCT03269994Trial comparisons
Cefoxitin vs Piperacillin-tazobactam: serious adverse events10 of 4005 of 378778NCT03269994Trial comparisons
Ertapenem Sodium vs Piperacillin/Tazobactam Sodium: serious adverse events17 of 27512 of 275550NCT01370616Trial comparisons
ZTI-01 vs Piperacillin Tazobactam: deaths from any cause0 of 2330 of 231464NCT02753946Trial comparisons
ZTI-01 vs Piperacillin Tazobactam: serious adverse events5 of 2336 of 231464NCT02753946Trial comparisons
Intermittent. Piperacillin/Tazobactam, Imipenem, Meropenem vs Prolonged Infusion. Continuous Piperacillin/Tazobactam, Extended Imipenem, Extended Meropenem: Number of Participants With Clinical Response
178 of 201169 of 202403NCT03019965Trial comparisons

Papers from its trials85

The papers the trials whose record names the drug list on ClinicalTrials.gov as their results (RESULT) or as drawn from them (DERIVED), results first, newest first.

PMIDListed asTrials listing itSource
40360262RESULT1PubMed
40261382RESULT1PubMed
37888913RESULT1PubMed
37877585RESULT1PubMed
37837651RESULT2PubMed
37256341RESULT1PubMed
37039790RESULT1PubMed
36525245RESULT1PubMed
35833959RESULT1PubMed
35315874RESULT1PubMed

Tests in its trials0

The tests ConductCognition runs that the trials whose record names the drug name in their registered outcomes, as ScienceGraph matched them. ConductCognition's list names the tests it runs, not every test a trial used.

None in this release.

Data dates

The date of each source this release read.

Open Targets
2026-09-18
Open Targets
ClinicalTrials.gov
2026-11-05
ClinicalTrials.gov
Results, from AACT
2026-03-23
AACT
Papers the trials list, from Trials
2026-11-12
Trials
Comparisons, from Trial comparisons
2026-03-23
Trial comparisons
Tests named in the trials, as ScienceGraph matched them
2026-11-12
ConductCognition

Sources 7

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ConductCognition's list of its testsOur own data
  • ClinicalTrials.govNo license stated
  • NLM's MeSHNLM's terms
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ConductCognition's list of its testsOur own data: ConductCognition's list of its tests, https://conductcognition.com
  • ClinicalTrials.govnone stated
  • NLM's MeSHNLM's
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this drug from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/drugs/v1/CHEMBL702

GET https://conductscience.org/api/drugs/v1/CHEMBL702/diseases?page=2