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Drug · CHEMBL930

GLUTAMINE

7 sourcespipelines-2026-09-18-0.3.1

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ConductScience Library. GLUTAMINE. Drugs and targets, record CHEMBL930. Release pipelines-2026-09-18-0.3.1, 18 Sept 2026. https://conductscience.org/library/drugs/CHEMBL930

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Drug

Names and IDs as ChEMBL gives them, through Open Targets.

Name
GLUTAMINE
ChEMBL
ChEMBL ID
CHEMBL930
ChEMBL
Type
Small molecule
ChEMBL
Brand names
Endari, Nutrestore
ChEMBL
Other names
FEMA NO. 3684, Glutamina, L-glutamine, Levoglutamide, NSC-27421
ChEMBL
DrugBank
DB00130
DrugBank
InChIKey
ZDXPYRJPNDTMRX-VKHMYHEASA-N
ChEMBL
Open Targets' highest stage
Approval, for 3 of its 42 diseases, from DailyMed and TTD
Open Targets

Targets0

The targets ChEMBL's mechanism records give for the drug, through Open Targets. A mechanism record says what the drug acts on, not how strongly.

None in this release.

Diseases42

The diseases Open Targets' clinical reports study the drug for, the most trial reports first. The stage is Open Targets', the highest any of its sources reports for the pair, and each row names the sources that report it.

DiseaseOpen Targets' stageStage reported byReportsOf them trialsIts drugs
sickle cell diseaseApprovalDailyMed76https://conductscience.org/library/drugs?q=MONDO_0011382
Duchenne muscular dystrophyPhase 3ClinicalTrials.gov33https://conductscience.org/library/drugs?q=MONDO_0010679
irritable bowel syndromePhase 2ClinicalTrials.gov22https://conductscience.org/library/drugs?q=MONDO_0005052
malnutritionPhase 3ClinicalTrials.gov22https://conductscience.org/library/drugs?q=EFO_0008572
type 2 diabetes mellitusPhase 1ClinicalTrials.gov22https://conductscience.org/library/drugs?q=MONDO_0005148
COVID-19Phase 3ClinicalTrials.gov11https://conductscience.org/library/drugs?q=MONDO_0100096
HyperammonemiaPhase 1ClinicalTrials.gov11https://conductscience.org/library/drugs?q=HP_0001987
aortic stenosisUnknownClinicalTrials.gov11https://conductscience.org/library/drugs?q=EFO_0000266
atopic eczemaEarly phase 1ClinicalTrials.gov11https://conductscience.org/library/drugs?q=MONDO_0004980
cerebral palsyUnknownClinicalTrials.gov11https://conductscience.org/library/drugs?q=MONDO_0006497

Trials83

Trials whose record names the drug by a name ChEMBL states, posted results first, then the largest. Open Targets read each trial's text to find its drugs. 1 more rests on that reading alone and is shown because the trial's posted result groups or NLM's indexing of its papers name the drug. 9 more that Open Targets linked to it are not shown, since the release's checks do not confirm them.

TrialTitlePhaseParticipantsResults first postedNamed asLinked bySource
NCT01179217A Phase III Safety and Efficacy Study of L-Glutamine to Treat Sickle Cell Disease or Sickle βo-thalassemiaPhase 32302017-08-10glutamineIts nameClinicalTrials.gov
NCT01414244Glutamine for the Treatment of Patients With Irritable Bowel SyndromePhase 21062017-08-09glutamineIts nameClinicalTrials.gov
NCT01952847Randomized Trial of Glutamine in Patients With Mucositis or EsophagitisPhase 3772022-06-15glutamineIts nameClinicalTrials.gov
NCT00125788L-Glutamine Therapy for Sickle Cell Anemia and Sickle ß0 ThalassemiaPhase 2702021-01-29l-glutamineIts nameClinicalTrials.gov
NCT04560309Role of Glutamine as Myocardial Protector in Elective On-Pump CABG Surgery With Low EFPhase 3602023-11-13glutamineIts nameClinicalTrials.gov
NCT00365768Glutamine in Treating Neuropathy Caused by Vincristine in Young Patients With Lymphoma, Leukemia, or Solid TumorsPhase 2562016-09-09glutamineIts nameClinicalTrials.gov
NCT01607879Use of β-hydroxy-β-methylbutyrate to Counteract Muscle Loss in Men With Prostate Cancer on Androgen AblationPhase 2482023-09-22glutamineIts nameClinicalTrials.gov
NCT01534663Supplementation of Glutamine and Fish Oil Versus Placebo in Patients With Heart FailurePhase 2/3312020-12-22glutamineIts nameClinicalTrials.gov
NCT00195013Randomized Placebo-Controlled Trial of Glutamine for Breast Cancer Patients With Peripheral NeuropathyPhase 3302017-08-18glutamineIts nameClinicalTrials.gov
NCT00131508Trial of Oral Glutamine in Patients With Sickle Cell AnemiaPhase 2272010-05-12glutamineIts nameClinicalTrials.gov

1 to 10 of 83

See all 83 trials

Comparisons in its trials29

Comparisons Trial comparisons calculated in the trials whose record names the drug, most participants first. A comparison in one of its trials does not always compare the drug, so read the two groups.

ComparisonGroup 1, with the outcomeGroup 2, with the outcomeParticipantsTrialSource
L-glutamine vs 100% Maltodextrin: serious adverse events118 of 15168 of 78229NCT01179217Trial comparisons
Glutamine vs Placebo: deaths from any cause0 of 540 of 52106NCT01414244Trial comparisons
Glutamine vs Placebo: serious adverse events0 of 540 of 52106NCT01414244Trial comparisons
Investigational Product vs Placebo: deaths from any cause1 of 370 of 3370NCT00125788Trial comparisons
Investigational Product vs Placebo: serious adverse events24 of 3721 of 3370NCT00125788Trial comparisons
Glutamine vs Control: deaths from any cause0 of 300 of 3060NCT04560309Trial comparisons
Glutamine vs Control: serious adverse events0 of 300 of 3060NCT04560309Trial comparisons
Arm I: Glutamine vs Arm II: Placebo: Incidence of Vincristine-induced Peripheral Neuropathy24 of 2425 of 2549NCT00365768Trial comparisons
Arm I: Glutamine vs Arm II: Placebo: Number of Participants With Progression of Neuropathy11 of 2419 of 2549NCT00365768Trial comparisons
Arm I: Glutamine vs Arm II: serious adverse events0 of 240 of 2549NCT00365768Trial comparisons

Papers from its trials65

The papers the trials whose record names the drug list on ClinicalTrials.gov as their results (RESULT) or as drawn from them (DERIVED), results first, newest first.

PMIDListed asTrials listing itSource
31502272RESULT1PubMed
27556065RESULT1PubMed
25811109RESULT1PubMed
25412338RESULT1PubMed
25208756RESULT1PubMed
25069463RESULT1PubMed
24898304RESULT1PubMed
24898300RESULT1PubMed
24870574RESULT1PubMed
24817675RESULT1PubMed

Tests in its trials0

The tests ConductCognition runs that the trials whose record names the drug name in their registered outcomes, as ScienceGraph matched them. ConductCognition's list names the tests it runs, not every test a trial used.

None in this release.

Data dates

The date of each source this release read.

Open Targets
2026-09-18
Open Targets
ClinicalTrials.gov
2026-11-05
ClinicalTrials.gov
Results, from AACT
2026-03-23
AACT
Papers the trials list, from Trials
2026-11-12
Trials
Comparisons, from Trial comparisons
2026-03-23
Trial comparisons
Tests named in the trials, as ScienceGraph matched them
2026-11-12
ConductCognition

Sources 7

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ConductCognition's list of its testsOur own data
  • ClinicalTrials.govNo license stated
  • NLM's MeSHNLM's terms
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ConductCognition's list of its testsOur own data: ConductCognition's list of its tests, https://conductcognition.com
  • ClinicalTrials.govnone stated
  • NLM's MeSHNLM's
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this drug from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/drugs/v1/CHEMBL930

GET https://conductscience.org/api/drugs/v1/CHEMBL930/diseases?page=2