Paper18130
Spectral evidence for 2,2,3-trichloro-oxirane formation during microsomal trichloroethylene oxidation.
Uehleke H and 3 others. Arch Toxicol, 1977. Cited by 39 papers, by iCite.
11 sourcespapers-2026-11-12-0.1.0
Download JSON
Cite this record
ConductScience Library. Spectral evidence for 2,2,3-trichloro-oxirane formation during microsomal trichloroethylene oxidation. Papers, record 18130. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/18130
Paper
PubMed's record of the paper, with iCite's citation figures. No abstract is shown.
- Title
- Spectral evidence for 2,2,3-trichloro-oxirane formation during microsomal trichloroethylene oxidation.
- PubMed
Topics13
NLM's MeSH indexing of the paper, its major topics first.
| MeSH term | Major |
|---|---|
| Epoxy Compounds | Major topic |
| Ethers, Cyclic | Major topic |
| Microsomes, Liver | Major topic |
| Trichloroethylene | Major topic |
| Animals | |
| In Vitro Techniques | |
| Light | |
| Male | |
| NADP | |
| Oxidation-Reduction | |
| Rabbits | |
| Spectrophotometry | |
| Time Factors |
Source PubMed
References28
The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.
| Order | PMID | Title | Journal | Year | In Papers | Source |
|---|---|---|---|---|---|---|
| 1 | 4,147,966 | Metabolic activation of halothane and its covalent binding to liver endoplasmic proteins in vitro. | Naunyn Schmiedebergs Arch Pharmacol | 1973 | https://conductscience.org/library/papers/4147966 | PubMed |
| 2 | 4,647,062 | Trichloroethylene exposure and trichloroethylene metabolites in urine and blood. | Arch Toxikol | 1972 | https://conductscience.org/library/papers/4647062 | PubMed |
| 3 | 4,404,917 | [Formation of chloroform from carbon tetrachloride in liver microsomes, lipid peroxidation and destruction of cytochrome P-450]. | Arch Toxikol | 1972 | https://conductscience.org/library/papers/4404917 | PubMed |
| 4 | 4,480,028 | Metabolism of trichloroethylene in man. II. Pharmacokinetics of metabolites. | Arch Toxicol | 1974 | https://conductscience.org/library/papers/4480028 | PubMed |
| 6 | 1,233,985 | Chemical reactivity, metabolic oxirane formation and biological reactivity of chlorinated ethylenes in the isolated perfused rat liver preparation. | Biochem Pharmacol | 1975 | https://conductscience.org/library/papers/1233985 | PubMed |
| 7 | 14,071,536 | THE METABOLISM OF 36C1-LABELLED TRICHLOROETHYLENE AND TETRACHLOROETHYLENE IN THE RAT. | Biochem Pharmacol | 1963 | https://conductscience.org/library/papers/14071536 | PubMed |
| 8 | 4,280,521 | The mechanism of halothane binding to microsomal cytochrome P450. | Naunyn Schmiedebergs Arch Pharmacol | 1974 | https://conductscience.org/library/papers/4280521 | PubMed |
| 9 | 4,363,358 | Enhancement of the hepatotoxicity of trichloroethylene by inducers of drug metabolism. | Res Commun Chem Pathol Pharmacol | 1974 | https://conductscience.org/library/papers/4363358 | PubMed |
| 10 | 3,152 | A comparative study on the irreversible binding of labeled halothane trichlorofluoromethane, chloroform, and carbon tetrachloride to hepatic protein and lipids in vitro and in vivo. | Arch Toxicol | 1975 | https://conductscience.org/library/papers/3152 | PubMed |
| 11 | 5,476,202 | Centrilobular hepatic necrosis and acute renal failure in "solvent sniffers". | Ann Intern Med | 1970 | https://conductscience.org/library/papers/5476202 | PubMed |
| 12 | 18,130 | Spectral evidence for 2,2,3-trichloro-oxirane formation during microsomal trichloroethylene oxidation. | Arch Toxicol | 1977 | https://conductscience.org/library/papers/18130 | PubMed |
| 13 | 13,844,890 | The toxicity of trichloroethylene. | J Occup Med | 1959 | https://conductscience.org/library/papers/13844890 | PubMed |
| 14 | 1,108,881 | Mutagenicity in vitro and potential carcinogenicity of chlorinated ethylenes as a function of metabolic oxiran formation. | Biochem Pharmacol | 1975 | https://conductscience.org/library/papers/1108881 | PubMed |
| 15 | 5,967,557 | Relative effects of various chlorinated hydrocarbons on liver and kidney function in mice. | Toxicol Appl Pharmacol | 1966 | https://conductscience.org/library/papers/5967557 | PubMed |
| 16 | 4,144,825 | Binding of 14 C-carbon tetrachloride to microsomal proteins in vitro and formation of CHC1 3 by reduced liver microsomes. | Xenobiotica | 1973 | https://conductscience.org/library/papers/4144825 | PubMed |
| 17 | 4,395,301 | [Behavior of different microsomal drug oxidations following inactivation of cytochrome P-450 by UV-irradiation or deoxycholate treatment]. | Hoppe Seylers Z Physiol Chem | 1970 | https://conductscience.org/library/papers/4395301 | PubMed |
| 18 | 4,280,271 | Cutaneous manifestations of trichloroethylene toxicity. | Arch Dermatol | 1974 | https://conductscience.org/library/papers/4280271 | PubMed |
| 19 | 5,332,897 | Trichlorethylene: a review. | Br J Ind Med | 1966 | https://conductscience.org/library/papers/5332897 | PubMed |
| 20 | 4,642,755 | Metabolism of trichloroethylene in man. I. The significance of trichloroethanol in long-term exposure conditions. | Arch Toxikol | 1972 | https://conductscience.org/library/papers/4642755 | PubMed |
| 21 | 4,685,263 | Metabolism, excretion and toxicology of trichloroethylene after inhalation. 1. Experimental exposure on rats. | Arch Toxikol | 1973 | https://conductscience.org/library/papers/4685263 | PubMed |
Cited by11
The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 39 citations.
| PMID | Title | Journal | Year | In Papers | Source |
|---|---|---|---|---|---|
| 7,429,647 | The effect of trichloroethylene on some serum-enzymes, on the cytoenzymological activity in leucocytes, and on the acid-base equilibrium. | Int Arch Occup Environ Health | 1980 | https://conductscience.org/library/papers/7429647 | PubMed |
| 6,893,145 | Trichloroethylene vapours do not produce dominant lethal mutations in male mice. | Arch Toxicol | 1980 | https://conductscience.org/library/papers/6893145 | PubMed |
| 6,830,310 | Human environmental exposure to trichloro- and tetrachloroethylene from water and air in Milan, Italy. | Arch Environ Contam Toxicol | 1983 | https://conductscience.org/library/papers/6830310 | PubMed |
| 6,197,950 | Interactions of trichloroethylene with DNA in vitro and with RNA and DNA of various mouse tissues in vivo. | Arch Toxicol | 1983 | https://conductscience.org/library/papers/6197950 | PubMed |
| 1,929,390 | Methanol suppression of trichloroethylene degradation by Methylosinus trichosporium (OB3b) and methane-oxidizing mixed cultures. | Appl Biochem Biotechnol | 1991 | https://conductscience.org/library/papers/1929390 | PubMed |
| 859,644 | Irreversible binding of 3-14C-antipyrine to hepatic protein in vivo and in metabolizing liver microsomes. | Naunyn Schmiedebergs Arch Pharmacol | 1977 | https://conductscience.org/library/papers/859644 | PubMed |
| 652,047 | Kinetics and metabolism of 2,2-diethylallylacetamide in dog and man. | Naunyn Schmiedebergs Arch Pharmacol | 1978 | https://conductscience.org/library/papers/652047 | PubMed |
| 578,705 | Irreversible binding of 14C-labelled trichloroethylene to mice liver constituents in vivo and in vitro. | Arch Toxicol | 1977 | https://conductscience.org/library/papers/578705 | PubMed |
| 373,707 | Mutagenic and alkylating metabolites of halo-ethylenes, chlorobutadienes and dichlorobutenes produced by rodent or human liver tissues. Evidence for oxirane formation by P450-linked microsomal mono-oxygenases. | Arch Toxicol | 1979 | https://conductscience.org/library/papers/373707 | PubMed |
| 157,359 | Vinyl chloride and trichloroethylene: comparison of alkylating effects of metabolites and induction of preneoplastic enzyme deficiencies in rat liver. | J Cancer Res Clin Oncol | 1979 | https://conductscience.org/library/papers/157359 | PubMed |
| 18,130 | Spectral evidence for 2,2,3-trichloro-oxirane formation during microsomal trichloroethylene oxidation. | Arch Toxicol | 1977 | https://conductscience.org/library/papers/18130 | PubMed |
Data dates
The date of each source this release read.
- Trials
- 2026-11-12
- Gene search
- 2026-11-11
- Pipelines
- 2026-09-18
None in this release
- Grants
- Trials
- Comments and corrections
- Genes
- Drugs
- Data
Sources 11
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- HGNCCC0
- iCiteCC BY 4.0
- NCBI GenePublic domain (US government)
- NIH RePORTER's grant and paper linksPublic domain
- Open TargetsCC0 1.0
- PMC's ID filePublic domain (US government)
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- HGNCCC0: https://www.genenames.org/about/license/
- iCiteCC BY 4.0
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this paper from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/papers/v1/18130
GET https://conductscience.org/api/papers/v1/18130/references?page=2