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Paper · 20101236

Integrative molecular profiling of triple negative breast cancers identifies amplicon drivers and potential therapeutic targets.

Turner N and 12 others. Oncogene, 2010. Cited by 328 papers, by iCite.

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ConductScience Library. Integrative molecular profiling of triple negative breast cancers identifies amplicon drivers and potential therapeutic targets. Papers, record 20101236. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/20101236

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Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title
Integrative molecular profiling of triple negative breast cancers identifies amplicon drivers and potential therapeutic targets.
PubMed
Journal
Oncogene
PubMed
Year
2010
PubMed
Publication types
Journal Article, Research Support, Non-U.S. Gov't
PubMed
Citations, by iCite
328
iCite
Relative citation ratio, by iCite
6.86
iCite
Revised in PubMed
2025-05-29
PubMed

Authors13

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

OrderAuthorForenameKindORCID iD
1Turner NN
2Lambros MBM B
3Horlings HMH M
4Pearson AA
5Sharpe RR
6Natrajan RR
7Geyer FCF C
8van Kouwenhove MM
9Kreike BB
10Mackay AA

1 to 10 of 13Source PubMed

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Topics18

NLM's MeSH indexing of the paper, its major topics first.

MeSH termMajor
Breast NeoplasmsMajor topic
Gene AmplificationMajor topic
Gene Expression Regulation, NeoplasticMajor topic
Animals
Apoptosis
Cell Line, Tumor
Cell Survival
Comparative Genomic Hybridization
Gene Dosage
Gene Expression Profiling
Genomics
Humans
Ligands
Phosphatidylinositol 3-Kinases
Receptor Protein-Tyrosine Kinases
Receptor, Fibroblast Growth Factor, Type 2
Reproducibility of Results
Signal Transduction

Source PubMed

Grants2

Each grant PubMed's record writes, matched to the NIH project NIH's grant and paper links name for this paper, and each of those links the record does not write.

Grant, as the record writes itAgencyCountryNIH projectStated by
A10038Cancer Research UKUnited KingdomPubMed
BREAST CANCER NOW RESEARCH CENTREBreast Cancer NowUnited KingdomPubMed

Source PubMed

Trials0

The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.

None in this release.

Comments and corrections0

PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.

None in this release.

References46

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

OrderPMIDTitleJournalYearIn PapersSource
117,577,043Pathological complete response in triple negative poorly differentiated invasive ductal breast carcinoma detected during pregnancy.J Clin Oncol2007https://conductscience.org/library/papers/17577043PubMed
217,276,656Resolving the resolution of array CGH.Genomics2007https://conductscience.org/library/papers/17276656PubMed
317,910,759Gene expression profiling and histopathological characterization of triple-negative/basal-like breast carcinomas.Breast Cancer Res2007https://conductscience.org/library/papers/17910759PubMed
418,089,785Integrated profiling of basal and luminal breast cancers.Cancer Res2007https://conductscience.org/library/papers/18089785PubMed
518,171,422Triple negative tumours: a critical review.Histopathology2008https://conductscience.org/library/papers/18171422PubMed
617,558,419Getting it right: designing microarray (and not 'microawry') comparative genomic hybridization studies for cancer research.Lab Invest2007https://conductscience.org/library/papers/17558419PubMed
716,687,925The basal phenotype of BRCA1-related breast cancer: past, present and future.Cell Cycle2006https://conductscience.org/library/papers/16687925PubMed
819,318,498Tiling path genomic profiling of grade 3 invasive ductal breast cancers.Clin Cancer Res2009https://conductscience.org/library/papers/19318498PubMed
918,757,403Inhibition of activated fibroblast growth factor receptor 2 in endometrial cancer cells induces cell death despite PTEN abrogation.Cancer Res2008https://conductscience.org/library/papers/18757403PubMed
1018,543,098Pattern of metastatic spread in triple-negative breast cancer.Breast Cancer Res Treat2009https://conductscience.org/library/papers/18543098PubMed

1 to 10 of 46

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Cited by192

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 328 citations.

PMIDTitleJournalYearIn PapersSource
42,769,774Metastatic Triple Negative Breast Cancer: Navigating a Rapidly Evolving Therapeutic Landscape.Oncol Res2026https://conductscience.org/library/papers/42769774PubMed
41,596,057DyVarMap: Integrating Conformational Dynamics and Interpretable Machine Learning for Cancer-Associated Missense Variant Classification in FGFR2.Bioengineering (Basel)2026https://conductscience.org/library/papers/41596057PubMed
41,463,252The Molecular Landscape and Utility of Multiomic Analyses in Triple-Negative Breast Cancer: Further Subtyping and Exploring Novel Biomarkers and Therapeutic Targets.Cancers (Basel)2025https://conductscience.org/library/papers/41463252PubMed
41,321,947Overexpression of ORAOV1 and its association with immunotherapy resistance in hepatocellular carcinoma.PeerJ2025https://conductscience.org/library/papers/41321947PubMed
41,318,657RAD51B-EZH2 axis as a potential therapeutic target for TNBC through cell fate conversion.Cell Death Dis2025https://conductscience.org/library/papers/41318657PubMed
40,244,488A comprehensive review on targeted therapies for triple negative breast cancer: an evidence-based treatment guideline.Discov Oncol2025https://conductscience.org/library/papers/40244488PubMed
39,596,875Lower FGFR2 mRNA Expression and Higher Levels of FGFR2 IIIc in HER2-Positive Breast Cancer.Biology (Basel)2024https://conductscience.org/library/papers/39596875PubMed
39,558,881Advances in the Understanding of the Pathogenesis of Triple-Negative Breast Cancer.Cancer Med2024https://conductscience.org/library/papers/39558881PubMed
39,272,660Triple-Negative Breast Cancer: Molecular Particularities Still a Challenge.Diagnostics (Basel)2024https://conductscience.org/library/papers/39272660PubMed
39,239,354Obtention of viable cell suspensions from breast cancer tumor biopsies for 3D chromatin conformation and single-cell transcriptome analysis.Front Mol Biosci2024https://conductscience.org/library/papers/39239354PubMed

1 to 10 of 192

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Genes50

The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.

GeneNCBI Gene IDLinked byIn GenesSource
AKT1207PubTator's text mininghttps://conductscience.org/library/genes/207NCBI Gene
ANXA5308PubTator's text mininghttps://conductscience.org/library/genes/308NCBI Gene
ATE111,101PubTator's text mininghttps://conductscience.org/library/genes/11101NCBI Gene
ATP5F1C509PubTator's text mininghttps://conductscience.org/library/genes/509NCBI Gene
BIRC5332PubTator's text mininghttps://conductscience.org/library/genes/332NCBI Gene
BRCA1672PubTator's text mininghttps://conductscience.org/library/genes/672NCBI Gene
BUB39,184PubTator's text mininghttps://conductscience.org/library/genes/9184NCBI Gene
CCND1595PubTator's text mininghttps://conductscience.org/library/genes/595NCBI Gene
CDC168,881PubTator's text mininghttps://conductscience.org/library/genes/8881NCBI Gene
CSNK1D1,453PubTator's text mininghttps://conductscience.org/library/genes/1453NCBI Gene

1 to 10 of 50

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Drugs0

The drugs whose trials, in the Pipelines release, list the paper.

None in this release.

Data0

The data bank entries PubMed's record names. Trial numbers are under Trials.

None in this release.

Data dates

The date of each source this release read.

PubMed
2026-11-06
PubMed
iCite
2026-11-05
iCite
PMC's ID file
2026-11-05
PMC's ID file
NIH RePORTER's grant and paper links
2026-11-01
NIH RePORTER's grant and paper links
Trials
2026-11-12
Gene search
2026-11-11
Pipelines
2026-09-18

Sources 11

  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • HGNCCC0
  • iCiteCC BY 4.0
  • NCBI GenePublic domain (US government)
  • NIH RePORTER's grant and paper linksPublic domain
  • Open TargetsCC0 1.0
  • PMC's ID filePublic domain (US government)
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • HGNCCC0: https://www.genenames.org/about/license/
  • iCiteCC BY 4.0
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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