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Paper · 20161824

Development of a HTRF kinase assay for determination of Syk activity.

Harbert C and 3 others. Curr Chem Genomics, 2008. Cited by 13 papers, by iCite.

11 sourcespapers-2026-11-12-0.1.0

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ConductScience Library. Development of a HTRF kinase assay for determination of Syk activity. Papers, record 20161824. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/20161824

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Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title
Development of a HTRF kinase assay for determination of Syk activity.
PubMed
Journal
Curr Chem Genomics
PubMed
Year
2008
PubMed
Publication types
Journal Article
PubMed
Citations, by iCite
13
iCite
Relative citation ratio, by iCite
0.32
iCite
Revised in PubMed
2021-10-20
PubMed

Authors4

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

OrderAuthorForenameKindORCID iD
1Harbert CChristopher
2Marshall JJeannette
3Soh SSharon
4Steger KKrista

Source PubMed

Topics0

NLM's MeSH indexing of the paper, its major topics first.

None in this release.

Grants0

Each grant PubMed's record writes, matched to the NIH project NIH's grant and paper links name for this paper, and each of those links the record does not write.

None in this release.

Trials0

The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.

None in this release.

Comments and corrections0

PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.

None in this release.

References17

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

OrderPMIDTitleJournalYearIn PapersSource
110,094,779Homogeneous proximity tyrosine kinase assays: scintillation proximity assay versus homogeneous time-resolved fluorescence.Anal Biochem1999https://conductscience.org/library/papers/10094779PubMed
210,689,303Tyrosine kinase SYK: essential functions for immunoreceptor signalling.Immunol Today2000https://conductscience.org/library/papers/10689303PubMed
312,669,029Issues and progress with protein kinase inhibitors for cancer treatment.Nat Rev Drug Discov2003https://conductscience.org/library/papers/12669029PubMed
416,356,459Comparative analysis of various in vitro COT kinase assay formats and their applications in inhibitor identification and characterization.Anal Biochem2006https://conductscience.org/library/papers/16356459PubMed
515,212,616Targeting Syk as a treatment for allergic and autoimmune disorders.Expert Opin Investig Drugs2004https://conductscience.org/library/papers/15212616PubMed
617,662,659Syk kinase as a treatment target for therapy in autoimmune diseases.Clin Immunol2007https://conductscience.org/library/papers/17662659PubMed
77,957,236Signal-transduction therapy. A novel approach to disease management.Eur J Biochem1994https://conductscience.org/library/papers/7957236PubMed
815,507,431A novel mode of Gleevec binding is revealed by the structure of spleen tyrosine kinase.J Biol Chem2004https://conductscience.org/library/papers/15507431PubMed
912,471,243The protein kinase complement of the human genome.Science2002https://conductscience.org/library/papers/12471243PubMed
1015,180,536The spleen tyrosine kinase (Syk) in human disease, implications for design of tyrosine kinase inhibitor based therapy.Curr Pharm Des2004https://conductscience.org/library/papers/15180536PubMed

1 to 10 of 17

See all 17 references

Cited by7

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 13 citations.

PMIDTitleJournalYearIn PapersSource
30,717,771Discovery and evaluation of ZT55, a novel highly-selective tyrosine kinase inhibitor of JAK2V617F against myeloproliferative neoplasms.J Exp Clin Cancer Res2019https://conductscience.org/library/papers/30717771PubMed
26,552,670Method for Assaying the Lipid Kinase Phosphatidylinositol-5-phosphate 4-kinase α in Quantitative High-Throughput Screening (qHTS) Bioluminescent Format.Methods Mol Biol2016https://conductscience.org/library/papers/26552670PubMed
26,501,901Bioluminescence Methods for Assaying Kinases in Quantitative High-Throughput Screening (qHTS) Format Applied to Yes1 Tyrosine Kinase, Glucokinase, and PI5P4Kα Lipid Kinase.Methods Mol Biol2016https://conductscience.org/library/papers/26501901PubMed
21,643,507Two High Throughput Screen Assays for Measurement of TNF-α in THP-1 Cells.Curr Chem Genomics2011https://conductscience.org/library/papers/21643507PubMed
20,161,833HTRF: A technology tailored for drug discovery - a review of theoretical aspects and recent applications.Curr Chem Genomics2009https://conductscience.org/library/papers/20161833PubMed
20,161,830Comparison on functional assays for Gq-coupled GPCRs by measuring inositol monophospate-1 and intracellular calcium in 1536-well plate format.Curr Chem Genomics2008https://conductscience.org/library/papers/20161830PubMed
20,161,828Cellular Ser/Thr-kinase assays using generic peptide substrates.Curr Chem Genomics2008https://conductscience.org/library/papers/20161828PubMed

Genes2

The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.

GeneNCBI Gene IDLinked byIn GenesSource
SYK6,850PubTator's text mininghttps://conductscience.org/library/genes/6850NCBI Gene
TXK7,294PubTator's text mininghttps://conductscience.org/library/genes/7294NCBI Gene

Drugs0

The drugs whose trials, in the Pipelines release, list the paper.

None in this release.

Data0

The data bank entries PubMed's record names. Trial numbers are under Trials.

None in this release.

Data dates

The date of each source this release read.

PubMed
2026-11-06
PubMed
iCite
2026-11-05
iCite
PMC's ID file
2026-11-05
PMC's ID file
NIH RePORTER's grant and paper links
2026-11-01
NIH RePORTER's grant and paper links
Trials
2026-11-12
Gene search
2026-11-11
Pipelines
2026-09-18

Sources 11

  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • HGNCCC0
  • iCiteCC BY 4.0
  • NCBI GenePublic domain (US government)
  • NIH RePORTER's grant and paper linksPublic domain
  • Open TargetsCC0 1.0
  • PMC's ID filePublic domain (US government)
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • HGNCCC0: https://www.genenames.org/about/license/
  • iCiteCC BY 4.0
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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