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Paper · 21193451

Metachronous colorectal cancer risk for mismatch repair gene mutation carriers: the advantage of more extensive colon surgery.

Parry S and 21 others. Gut, 2011. Cited by 206 papers, by iCite.

11 sourcespapers-2026-11-12-0.1.0

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ConductScience Library. Metachronous colorectal cancer risk for mismatch repair gene mutation carriers: the advantage of more extensive colon surgery. Papers, record 21193451. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/21193451

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Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title
Metachronous colorectal cancer risk for mismatch repair gene mutation carriers: the advantage of more extensive colon surgery.
PubMed
Journal
Gut
PubMed
Year
2011
PubMed
Publication types
Journal Article, Research Support, N.I.H., Extramural
PubMed
Citations, by iCite
206
iCite
Relative citation ratio, by iCite
5.47
iCite
Revised in PubMed
2024-06-10
PubMed

Authors22

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

OrderAuthorForenameKindORCID iD
1Parry SSusan
2Win AKAung Ko
3Parry BBryan
4Macrae FAFinlay A
5Gurrin LCLyle C
6Church JMJames M
7Baron JAJohn A
8Giles GGGraham G
9Leggett BABarbara A
10Winship IIngrid

1 to 10 of 22Source PubMed

See all 22 authors

Topics26

NLM's MeSH indexing of the paper, its major topics first.

MeSH termMajor
Colorectal Neoplasms, Hereditary NonpolyposisMajor topic
DNA Mismatch RepairMajor topic
Adaptor Proteins, Signal Transducing
Adenosine Triphosphatases
Adult
Age Distribution
Aged
Colectomy
Colonoscopy
DNA Mutational Analysis
DNA Repair Enzymes
DNA-Binding Proteins
Epidemiologic Methods
Female
Heterozygote
Humans
Male
Middle Aged
Mismatch Repair Endonuclease PMS2
MutL Protein Homolog 1
MutS Homolog 2 Protein
Neoplasm Staging
Neoplasms, Second Primary
Nuclear Proteins
Sex Distribution
Young Adult

Source PubMed

Grants10

Each grant PubMed's record writes, matched to the NIH project NIH's grant and paper links name for this paper, and each of those links the record does not write.

Grant, as the record writes itAgencyCountryNIH projectStated bySource
U01 CA074799NCI NIH HHSUnited StatesU01CA074799PubMed and NIHNIH RePORTER
U01 CA074794NCI NIH HHSUnited StatesU01CA074794PubMed and NIHNIH RePORTER
U01 CA097735NCI NIH HHSUnited StatesU01CA097735PubMed and NIHNIH RePORTER
U01 CA074783NCI NIH HHSUnited StatesU01CA074783PubMed and NIHNIH RePORTER
U01 CA074806NCI NIH HHSUnited StatesU01CA074806PubMed and NIHNIH RePORTER
UO1 CA074799NCI NIH HHSUnited StatesU01CA074799PubMed and NIHNIH RePORTER
U24 CA074794NCI NIH HHSUnited StatesU01CA074794PubMed and NIHNIH RePORTER
P30 CA071789NCI NIH HHSUnited StatesP30CA071789PubMed and NIHNIH RePORTER
U01 CA074800NCI NIH HHSUnited StatesU01CA074800PubMed and NIHNIH RePORTER
U24CA074794NIHNIH RePORTER

Trials0

The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.

None in this release.

Comments and corrections1

PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.

KindPMIDTitleIn Papers
Comment in21,873,468Cumulative incidence of metachronous colorectal cancer risk for mismatch repair gene mutation carriers is overestimated.https://conductscience.org/library/papers/21873468

Source PubMed

References20

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

OrderPMIDTitleJournalYearIn PapersSource
120,206,180One to 2-year surveillance intervals reduce risk of colorectal cancer in families with Lynch syndrome.Gastroenterology2010https://conductscience.org/library/papers/20206180PubMed
220,028,993Risks of Lynch syndrome cancers for MSH6 mutation carriers.J Natl Cancer Inst2010https://conductscience.org/library/papers/20028993PubMed
312,473,880Surveillance for hereditary nonpolyposis colorectal cancer: a long-term study on 114 families.Dis Colon Rectum2002https://conductscience.org/library/papers/12473880PubMed
414,633,956Decision analysis in the surgical treatment of colorectal cancer due to a mismatch repair gene defect.Gut2003https://conductscience.org/library/papers/14633956PubMed
510,784,581Controlled 15-year trial on screening for colorectal cancer in families with hereditary nonpolyposis colorectal cancer.Gastroenterology2000https://conductscience.org/library/papers/10784581PubMed
610,348,829New clinical criteria for hereditary nonpolyposis colorectal cancer (HNPCC, Lynch syndrome) proposed by the International Collaborative group on HNPCC.Gastroenterology1999https://conductscience.org/library/papers/10348829PubMed
712,792,437Patterns of surgery in patients belonging to amsterdam-positive families.Dis Colon Rectum2003https://conductscience.org/library/papers/12792437PubMed
817,327,285Guidelines for the clinical management of Lynch syndrome (hereditary non-polyposis cancer).J Med Genet2007https://conductscience.org/library/papers/17327285PubMed
917,003,399Recommendations for the care of individuals with an inherited predisposition to Lynch syndrome: a systematic review.JAMA2006https://conductscience.org/library/papers/17003399PubMed
1010,877,330A note on robust variance estimation for cluster-correlated data.Biometrics2000https://conductscience.org/library/papers/10877330PubMed

1 to 10 of 20

See all 20 references

Cited by108

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 206 citations.

PMIDTitleJournalYearIn PapersSource
42,882,890Second Primary Malignancies in Gastrointestinal Cancer Survivors: Epidemiology, Risk Factors, and Future Prediction Models.Cancers (Basel)2026https://conductscience.org/library/papers/42882890PubMed
41,287,493Cost-Utility Analysis of Universal Lynch Syndrome Screening among Colorectal Cancer Patients in a Low-Middle-Income Country.Yonsei Med J2025https://conductscience.org/library/papers/41287493PubMed
40,873,251Contemporary Surgical Management of Colorectal Cancer in Lynch Syndrome: Considering the Implications of Known Genotype.ANZ J Surg2025https://conductscience.org/library/papers/40873251PubMed
40,765,665Segmental versus Extended Resection for Colon Cancer in Lynch Syndrome.Clin Colon Rectal Surg2025https://conductscience.org/library/papers/40765665PubMed
40,292,001Hereditary Colorectal Cancer: From Diagnosis to Surgical Options.Clin Colon Rectal Surg2025https://conductscience.org/library/papers/40292001PubMed
40,231,433Metachronous colorectal cancer risks after extended or segmental resection in MLH1, MSH2, and MSH6 Lynch syndrome: multicentre study from the Prospective Lynch Syndrome Database.Br J Surg2025https://conductscience.org/library/papers/40231433PubMed
40,158,390Intratumoural pks+Escherichia coli is associated with risk of metachronous colorectal cancer and adenoma development in people with Lynch syndrome.EBioMedicine2025https://conductscience.org/library/papers/40158390PubMed
39,906,700DMMR status and synchronous lesions predicts metachronous lesions after curative resection for rectal cancer.Front Surg2025https://conductscience.org/library/papers/39906700PubMed
39,859,102Lynch Syndrome-Impact of the Type of Deficient Mismatch Repair Gene Mutation on Diagnosis, Clinical Presentation, Surveillance and Therapeutic Approaches.Medicina (Kaunas)2025https://conductscience.org/library/papers/39859102PubMed
39,502,732High risk of multiple gastric cancers in Japanese individuals with Lynch syndrome.Ann Gastroenterol Surg2024https://conductscience.org/library/papers/39502732PubMed

1 to 10 of 108

See all 108 cited by

Genes4

The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.

GeneNCBI Gene IDLinked byIn GenesSource
MLH14,292PubTator's text mininghttps://conductscience.org/library/genes/4292NCBI Gene
MSH24,436PubTator's text mininghttps://conductscience.org/library/genes/4436NCBI Gene
MSH62,956PubTator's text mininghttps://conductscience.org/library/genes/2956NCBI Gene
PMS25,395PubTator's text mininghttps://conductscience.org/library/genes/5395NCBI Gene

Drugs0

The drugs whose trials, in the Pipelines release, list the paper.

None in this release.

Data0

The data bank entries PubMed's record names. Trial numbers are under Trials.

None in this release.

Data dates

The date of each source this release read.

PubMed
2026-11-06
PubMed
iCite
2026-11-05
iCite
PMC's ID file
2026-11-05
PMC's ID file
NIH RePORTER's grant and paper links
2026-11-01
NIH RePORTER's grant and paper links
Trials
2026-11-12
Gene search
2026-11-11
Pipelines
2026-09-18

Sources 11

  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • HGNCCC0
  • iCiteCC BY 4.0
  • NCBI GenePublic domain (US government)
  • NIH RePORTER's grant and paper linksPublic domain
  • Open TargetsCC0 1.0
  • PMC's ID filePublic domain (US government)
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • HGNCCC0: https://www.genenames.org/about/license/
  • iCiteCC BY 4.0
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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