ConductScience.org, home
Papers
API referenceFor AI assistants

Paper · 25979474

WGE: a CRISPR database for genome engineering.

Hodgkins A and 6 others. Bioinformatics, 2015. Cited by 150 papers, by iCite.

11 sourcespapers-2026-11-12-0.1.0

Download JSON
Cite this record

ConductScience Library. WGE: a CRISPR database for genome engineering. Papers, record 25979474. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/25979474

On this page

Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title
WGE: a CRISPR database for genome engineering.
PubMed
Journal
Bioinformatics
PubMed
Year
2015
PubMed
Publication types
Journal Article, Research Support, N.I.H., Extramural, Research Support, Non-U.S. Gov't
PubMed
Citations, by iCite
150
iCite
Relative citation ratio, by iCite
3.76
iCite
Revised in PubMed
2024-01-04
PubMed

Authors7

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

OrderAuthorForenameKindORCID iD
1Hodgkins AAlex
2Farne AAnna
3Perera SSajith
4Grego TTiago
5Parry-Smith DJDavid J
6Skarnes WCWilliam C
7Iyer VVivek

Source PubMed

Topics11

NLM's MeSH indexing of the paper, its major topics first.

MeSH termMajor
CRISPR-Cas SystemsMajor topic
Clustered Regularly Interspaced Short Palindromic RepeatsMajor topic
Databases, FactualMajor topic
Gene Expression RegulationMajor topic
Genetic VectorsMajor topic
GenomeMajor topic
RNA EditingMajor topic
Animals
Humans
Mice
Software

Source PubMed

Grants2

Each grant PubMed's record writes, matched to the NIH project NIH's grant and paper links name for this paper, and each of those links the record does not write.

Grant, as the record writes itAgencyCountryNIH projectStated bySource
Wellcome TrustUnited KingdomPubMedPubMed
1 U54 HG006370-01NHGRI NIH HHSUnited StatesU54HG006370PubMed and NIHNIH RePORTER

Trials0

The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.

None in this release.

Comments and corrections0

PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.

None in this release.

References12

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

OrderPMIDTitleJournalYearIn PapersSource
122,388,286Fast gapped-read alignment with Bowtie 2.Nat Methods2012https://conductscience.org/library/papers/22388286PubMed
220,435,679ZiFiT (Zinc Finger Targeter): an updated zinc finger engineering tool.Nucleic Acids Res2010https://conductscience.org/library/papers/20435679PubMed
319,363,495Enzymatic assembly of DNA molecules up to several hundred kilobases.Nat Methods2009https://conductscience.org/library/papers/19363495PubMed
424,861,617CHOPCHOP: a CRISPR/Cas9 and TALEN web tool for genome editing.Nucleic Acids Res2014https://conductscience.org/library/papers/24861617PubMed
524,906,146Development and applications of CRISPR-Cas9 for genome engineering.Cell2014https://conductscience.org/library/papers/24906146PubMed
625,414,360CRISPRdirect: software for designing CRISPR/Cas guide RNA with reduced off-target sites.Bioinformatics2015https://conductscience.org/library/papers/25414360PubMed
724,584,192Efficient genome modification by CRISPR-Cas9 nickase with minimal off-target effects.Nat Methods2014https://conductscience.org/library/papers/24584192PubMed
824,481,216E-CRISP: fast CRISPR target site identification.Nat Methods2014https://conductscience.org/library/papers/24481216PubMed
924,316,576Ensembl 2014.Nucleic Acids Res2014https://conductscience.org/library/papers/24316576PubMed
1024,199,189A guide RNA sequence design platform for the CRISPR/Cas9 system for model organism genomes.Biomed Res Int2013https://conductscience.org/library/papers/24199189PubMed

1 to 10 of 12

See all 12 references

Cited by124

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 150 citations.

PMIDTitleJournalYearIn PapersSource
42,947,239Phenotype rescue through the restoration of full-length dystrophin using CRISPR/Cas9 genome editing in Duchenne muscular dystrophy patient-derived iPSCs carrying the deletion of two exons.Genome Med2026https://conductscience.org/library/papers/42947239PubMed
42,935,787Deletion of a rheumatoid arthritis risk enhancer in mouse disrupts Bim expression and immune homeostasis.EULAR Rheumatol Open2026https://conductscience.org/library/papers/42935787PubMed
41,686,830A VPS33B CRISPR knockout study: In vitro evidence of an adhesion defect.PLoS One2026https://conductscience.org/library/papers/41686830PubMed
41,554,648Kv4.2V404M Mutation Induces Epileptiform Activity and Multiple Behavioral Abnormalities in Heterozygous Knock-in Mice.J Neurosci2026https://conductscience.org/library/papers/41554648PubMed
41,422,144Missense variant in TTBK2 kinase domain causes loss of function and impaired protein phosphorylation.Sci Rep2025https://conductscience.org/library/papers/41422144PubMed
41,353,404A next-generation dual guide CRISPR system for genetic interaction library screening.Nat Commun2025https://conductscience.org/library/papers/41353404PubMed
41,330,380A genome-scale single-cell CRISPRi map of trans gene regulation across human pluripotent stem cell lines.Cell Genom2026https://conductscience.org/library/papers/41330380PubMed
41,129,595A distal enhancer of Pparα regulates thermogenesis and mitochondrial function in brown fat.PLoS Genet2025https://conductscience.org/library/papers/41129595PubMed
41,017,815Advancing CRISPR with deep learning: A comprehensive review of models and databases.Mol Ther Nucleic Acids2025https://conductscience.org/library/papers/41017815PubMed
40,761,563Unlocking the potential of CRISPR tools and databases for precision genome editing.Front Plant Sci2025https://conductscience.org/library/papers/40761563PubMed

1 to 10 of 124

See all 124 cited by

Genes1

The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.

GeneNCBI Gene IDLinked byIn Genes
APOE348PubTator's text mininghttps://conductscience.org/library/genes/348

Source NCBI Gene

Drugs0

The drugs whose trials, in the Pipelines release, list the paper.

None in this release.

Data0

The data bank entries PubMed's record names. Trial numbers are under Trials.

None in this release.

Data dates

The date of each source this release read.

PubMed
2026-11-06
PubMed
iCite
2026-11-05
iCite
PMC's ID file
2026-11-05
PMC's ID file
NIH RePORTER's grant and paper links
2026-11-01
NIH RePORTER's grant and paper links
Trials
2026-11-12
Gene search
2026-11-11
Pipelines
2026-09-18

Sources 11

  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • HGNCCC0
  • iCiteCC BY 4.0
  • NCBI GenePublic domain (US government)
  • NIH RePORTER's grant and paper linksPublic domain
  • Open TargetsCC0 1.0
  • PMC's ID filePublic domain (US government)
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • HGNCCC0: https://www.genenames.org/about/license/
  • iCiteCC BY 4.0
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this paper from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/papers/v1/25979474

GET https://conductscience.org/api/papers/v1/25979474/cited_by?page=2

API referenceFor AI assistants