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Paper311007

Direct evidence for loss of human suppressor cells during active autoimmune disease.

Strelkauskas AJ and 4 others. Proc Natl Acad Sci U S A, 1978. Cited by 221 papers, by iCite.

11 sourcespapers-2026-11-12-0.1.0

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ConductScience Library. Direct evidence for loss of human suppressor cells during active autoimmune disease. Papers, record 311007. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/311007

Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title
Direct evidence for loss of human suppressor cells during active autoimmune disease.
PubMed
Journal
Proc Natl Acad Sci U S A
PubMed
Year
1978
PubMed
Publication types
Journal Article, Research Support, U.S. Gov't, P.H.S.
PubMed
Citations, by iCite
221
iCite
Relative citation ratio, by iCite
8.26
iCite
Revised in PubMed
2021-12-03
PubMed

Authors5

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

OrderAuthorForenameKindORCID iD
1Strelkauskas AJA J
2Callery RTR T
3McDowell JJ
4Borel YY
5Schlossman SFS F

Source PubMed

Topics12

NLM's MeSH indexing of the paper, its major topics first.

MeSH termMajor
Arthritis, JuvenileMajor topic
T-LymphocytesMajor topic
Adolescent
Adult
Autoantibodies
B-Lymphocytes
Child
Child, Preschool
Female
Humans
Immunosuppression Therapy
Male

Source PubMed

References34

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

OrderPMIDTitleJournalYearIn PapersSource
113,638,767Prognosis in Still's disease.Bull Rheum Dis1959https://conductscience.org/library/papers/13638767PubMed
272,775Specific enrichment of the suppressor T cell bearing I-J determinants: parallel functional and serological characterizations.J Exp Med1977https://conductscience.org/library/papers/72775PubMed
375,232A suppressor T cell of the mixed lymphocyte reaction in man specific for the stimulating alloantigen. Evidence that identity at HLA-D between suppressor and responder is required for suppression.J Exp Med1978https://conductscience.org/library/papers/75232PubMed
468,998A suppressor T cell in the human mixed lymphocyte reaction.J Exp Med1977https://conductscience.org/library/papers/68998PubMed
519,534Selective loss of suppressor cell function in New Zealand mice induced by NTA.J Immunol1977https://conductscience.org/library/papers/19534PubMed
6197,528Suppressor cell regulation of immune response to tumors: abrogation by adult thymectomy.Proc Natl Acad Sci U S A1977https://conductscience.org/library/papers/197528PubMed
7147,908Two functionally distinct subpopulations of human T cells that collaborate in the generation of cytotoxic cells responsible for cell-mediated lympholysis.J Immunol1978https://conductscience.org/library/papers/147908PubMed
8147,907Isolation and characterization of naturally occurring subclasses of human peripheral blood T cells with regulatory functions.J Immunol1978https://conductscience.org/library/papers/147907PubMed
9410,029Potentiation of a primary in vivo antibody response by alloantisera against gene products of the I region of the H-2 complex.Proc Natl Acad Sci U S A1977https://conductscience.org/library/papers/410029PubMed
10352,583Loss of suppressor T-lymphocyte function in patients with systemic lupus erythematosus (SLE).Clin Exp Immunol1978https://conductscience.org/library/papers/352583PubMed
11336,837T-cell regulation of human peripheral blood B-cells responsiveness.J Exp Med1977https://conductscience.org/library/papers/336837PubMed
12306,406Immunoregulatory circuits among T-cell sets. II. Physiologic role of feedback inhibition in vivo: absence in NZB mice.J Exp Med1978https://conductscience.org/library/papers/306406PubMed
13306,405Immunoregulatory circuits among T-cell sets. I. T-helper cells induce other T-cell sets to exert feedback inhibition.J Exp Med1978https://conductscience.org/library/papers/306405PubMed
14302,190Regulation of cellular and humoral immune responses by T-cell subclasses.Cold Spring Harb Symp Quant Biol1977https://conductscience.org/library/papers/302190PubMed
15270,747Reduction of syngeneic tumor growth by an anti-I-J-alloantiserum.Proc Natl Acad Sci U S A1977https://conductscience.org/library/papers/270747PubMed
16830,659Suppressor function of peripheral blood mononuclear cells in normal individuals and in patients with systemic lupus erythematosus.J Clin Invest1977https://conductscience.org/library/papers/830659PubMed
17824,081Assessment of a B-cell function in chronic lymphocytic leukemia.Clin Immunol Immunopathol1976https://conductscience.org/library/papers/824081PubMed
18792,341Subpopulations of human T cells identified by receptors for immunoglobulins and mitogen responsiveness.J Immunol1976https://conductscience.org/library/papers/792341PubMed
194,137,918Role of suppressor T cells in pathogenesis of common variable hypogammaglobulinaemia.Lancet1974https://conductscience.org/library/papers/4137918PubMed
204,133,847Antigen-secreting cells: enumeration of immunoglobulin-allotype-secreting cells in nonimmunized rabbits by means of hybrid-antibody-coated erythrocytes in a reverse hemolytic plaque assay.Proc Natl Acad Sci U S A1974https://conductscience.org/library/papers/4133847PubMed

See all 34 references

Cited by45

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 221 citations.

PMIDTitleJournalYearIn PapersSource
8,778,211Immunopathogenesis of juvenile rheumatoid arthritis: role of T cells and MHC.Immunol Res1995https://conductscience.org/library/papers/8778211PubMed
7,165,998Lymphocyte responses in juvenile chronic arthritis and Behçet's disease--cell number requirements and effects of glucocorticosteroid therapy.Clin Exp Immunol1982https://conductscience.org/library/papers/7165998PubMed
7,044,628Glycaemic control and suppressor cell activity in patients with insulin-dependent diabetes mellitus.Clin Exp Immunol1982https://conductscience.org/library/papers/7044628PubMed
7,041,302Immune mechanisms in atopic dermatitis.Springer Semin Immunopathol1981https://conductscience.org/library/papers/7041302PubMed
7,032,769Autoantibodies to a regulatory T cell subset in human ageing.Clin Exp Immunol1981https://conductscience.org/library/papers/7032769PubMed
7,019,055Effects of functionally-distinct T-cell subsets on the maturation of null cells in man.Immunology1981https://conductscience.org/library/papers/7019055PubMed
6,978,218B and T cell involvement in anti-acetylcholine receptor antibody formation in myasthenia gravis.Clin Exp Immunol1981https://conductscience.org/library/papers/6978218PubMed
6,967,515Immune disease and HLA associations with myasthenia gravis.J Neurol Neurosurg Psychiatry1980https://conductscience.org/library/papers/6967515PubMed
6,939,412Lymphocytotoxins in rheumatoid arthritis: prevalence, lymphocyte specificity, and HLA-DR antigens.Ann Rheum Dis1981https://conductscience.org/library/papers/6939412PubMed
6,766,468Familial rheumatoid arthritis: linkage of HLA to disease susceptibility locus in four families where proband presented with juvenile rheumatoid arthritis.J Clin Invest1980https://conductscience.org/library/papers/6766468PubMed
6,751,633Spontaneous plaque forming cells in the peripheral blood of patients with systemic lupus erythematosus.Clin Exp Immunol1982https://conductscience.org/library/papers/6751633PubMed
6,610,688Mononuclear-cell subsets in human idiopathic crescentic glomerulonephritis (ICGN): analysis in tissue sections with monoclonal antibodies.J Clin Immunol1984https://conductscience.org/library/papers/6610688PubMed
6,600,706Immunity to homologous collagens and cartilage proteoglycans in rabbits.Immunology1983https://conductscience.org/library/papers/6600706PubMed
6,461,299Immunoregulatory T cells in the peripheral blood of patients with Bechterew's syndrome.Ann Rheum Dis1982https://conductscience.org/library/papers/6461299PubMed
6,460,784Autoimmune blood dyscrasias in five patients with hypogammaglobulinemia: response of neutropenia to vincristine.J Clin Immunol1981https://conductscience.org/library/papers/6460784PubMed
6,459,117Altered cellular immunity and suppressor cell activity in patients with primary retinitis pigmentosa.Br J Ophthalmol1981https://conductscience.org/library/papers/6459117PubMed
6,456,877Spontaneous suppressor cell function in inflammatory bowel disease.Dig Dis Sci1981https://conductscience.org/library/papers/6456877PubMed
6,452,237Relationship between T cell subpopulations and the mitogen responsiveness and suppressor cell function of peripheral blood mononuclear cells in normal individuals.Clin Exp Immunol1980https://conductscience.org/library/papers/6452237PubMed
6,451,634Autoantibody to an immunoregulatory inducer population in patients with juvenile rheumatoid arthritis.J Clin Invest1981https://conductscience.org/library/papers/6451634PubMed
6,451,338Immune regulation in inflammatory bowel disease: absence of a serum inhibitor of suppressor cell function.Clin Exp Immunol1980https://conductscience.org/library/papers/6451338PubMed

See all 45 cited by

Data dates

The date of each source this release read.

PubMed
2026-11-06
PubMed
iCite
2026-11-05
iCite
PMC's ID file
2026-11-05
PMC's ID file
NIH RePORTER's grant and paper links
2026-11-01
NIH RePORTER's grant and paper links
Trials
2026-11-12
Gene search
2026-11-11
Pipelines
2026-09-18

None in this release

  • Grants
  • Trials
  • Comments and corrections
  • Genes
  • Drugs
  • Data

Sources 11

  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • HGNCCC0
  • iCiteCC BY 4.0
  • NCBI GenePublic domain (US government)
  • NIH RePORTER's grant and paper linksPublic domain
  • Open TargetsCC0 1.0
  • PMC's ID filePublic domain (US government)
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • HGNCCC0: https://www.genenames.org/about/license/
  • iCiteCC BY 4.0
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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