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Paper · 31350295

The Tumor Microenvironment Innately Modulates Cancer Progression.

Hinshaw DC and 1 other. Cancer Res, 2019. Cited by 2,587 papers, by iCite.

11 sourcespapers-2026-11-12-0.1.0

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ConductScience Library. The Tumor Microenvironment Innately Modulates Cancer Progression. Papers, record 31350295. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/31350295

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Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title
The Tumor Microenvironment Innately Modulates Cancer Progression.
PubMed
Journal
Cancer Res
PubMed
Year
2019
PubMed
Publication types
Journal Article, Research Support, N.I.H., Extramural, Research Support, U.S. Gov't, Non-P.H.S., Review
PubMed
Citations, by iCite
2,587
iCite
Relative citation ratio, by iCite
106
iCite
Revised in PubMed
2023-07-01
PubMed

Authors2

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

OrderAuthorForenameKindORCID iD
1Hinshaw DCDominique C
2Shevde LALalita A

Source PubMed

Topics5

NLM's MeSH indexing of the paper, its major topics first.

MeSH termMajor
Immunity, InnateMajor topic
NeoplasmsMajor topic
Tumor MicroenvironmentMajor topic
Animals
Humans

Source PubMed

Grants3

Each grant PubMed's record writes, matched to the NIH project NIH's grant and paper links name for this paper, and each of those links the record does not write.

Grant, as the record writes itAgencyCountryNIH projectStated bySource
P30 CA013148NCI NIH HHSUnited StatesP30CA013148PubMed and NIHNIH RePORTER
R01 CA169202NCI NIH HHSUnited StatesR01CA169202PubMed and NIHNIH RePORTER
T32 AI007051NIAID NIH HHSUnited StatesT32AI007051PubMedNIH RePORTER

Trials2

The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.

TrialTitleThe trial lists it asNamed in the paper's recordSource
NCT06967662Selective Plasma Adsorption of Extracellular DNA in Prevention of Intraoperative Metastasis in Pancreatic Cancer (Pilot Study)BackgroundClinicalTrials.gov
NCT07045610Primary Resistance Mechanisms of ALK TKIsBackgroundClinicalTrials.gov

Comments and corrections0

PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.

None in this release.

References100

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

OrderPMIDTitleJournalYearIn PapersSource
111,117,911Natural cytotoxic activity of peripheral-blood lymphocytes and cancer incidence: an 11-year follow-up study of a general population.Lancet2000https://conductscience.org/library/papers/11117911PubMed
212,200,067Pathogen-specific regulatory T cells provoke a shift in the Th1/Th2 paradigm in immunity to infectious diseases.Trends Immunol2002https://conductscience.org/library/papers/12200067PubMed
312,615,891Tolerogenic dendritic cells.Annu Rev Immunol2003https://conductscience.org/library/papers/12615891PubMed
415,466,195A paracrine loop between tumor cells and macrophages is required for tumor cell migration in mammary tumors.Cancer Res2004https://conductscience.org/library/papers/15466195PubMed
515,958,574Macrophages promote the invasion of breast carcinoma cells via a colony-stimulating factor-1/epidermal growth factor paracrine loop.Cancer Res2005https://conductscience.org/library/papers/15958574PubMed
617,438,063Breast cancer instructs dendritic cells to prime interleukin 13-secreting CD4+ T cells that facilitate tumor development.J Exp Med2007https://conductscience.org/library/papers/17438063PubMed
718,262,431Dendritic cell vaccines in melanoma: from promise to proof?Crit Rev Oncol Hematol2008https://conductscience.org/library/papers/18262431PubMed
818,417,738Type I NKT cells protect (and type II NKT cells suppress) the host's innate antitumor immune response to a B-cell lymphoma.Blood2008https://conductscience.org/library/papers/18417738PubMed
918,835,032Tumor-targeted interferon-alpha delivery by Tie2-expressing monocytes inhibits tumor growth and metastasis.Cancer Cell2008https://conductscience.org/library/papers/18835032PubMed
1018,836,473The Janus face of dendritic cells in cancer.Oncogene2008https://conductscience.org/library/papers/18836473PubMed

1 to 10 of 100

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Cited by2,116

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 2,587 citations.

PMIDTitleJournalYearIn PapersSource
42,980,878Integrative molecular profiling of TAM receptors and STAT-SOCS signaling in thymic epithelial tumors.Med Oncol2026https://conductscience.org/library/papers/42980878PubMed
42,974,114Mechanisms and Therapeutic Potential of Resveratrol: Focus on its Effect on Leukemia.Onco Targets Ther2026https://conductscience.org/library/papers/42974114PubMed
42,958,602Glioblastoma as a dynamic tumor ecosystem: from molecular alterations to therapeutic translation.Exp Hematol Oncol2026https://conductscience.org/library/papers/42958602PubMed
42,948,630Biomimetic M1 macrophage Membrane-Modified liposomes Co-delivering ponatinib and ginsenoside Rg3 for inhibition of breast cancer lung metastasis.J Ginseng Res2026https://conductscience.org/library/papers/42948630PubMed
42,948,347Intelligent nano delivery systems: Classification, stimuli-responsive mechanisms, and therapeutic applications in critical illnesses.Acta Pharm Sin B2026https://conductscience.org/library/papers/42948347PubMed
42,938,943Targeting Polyploid Giant Cancer Cells (PGCCs) to Prevent Cancer Recurrence: Opportunities for Nanomedicine.Cancers (Basel)2026https://conductscience.org/library/papers/42938943PubMed
42,935,572Influencing the exposome, patient macroenvironment, tumor microenvironment through-line to improve clinical outcomes.Front Oncol2026https://conductscience.org/library/papers/42935572PubMed
42,930,173Cancer Immunotherapy and Immune-Related Adverse Events: Focusing on Non-Small Cell Lung Cancer.Curr Oncol2026https://conductscience.org/library/papers/42930173PubMed
42,926,835ATG16L2 as a prognostic biomarker and therapeutic target in kidney renal clear cell carcinoma.iScience2026https://conductscience.org/library/papers/42926835PubMed
42,920,923Senescence and tumor immunology: A multifaceted interplay of influence.iScience2026https://conductscience.org/library/papers/42920923PubMed

1 to 10 of 2,116

See all 2,116 cited by

Genes170

The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.

GeneNCBI Gene IDLinked byIn GenesSource
ADORA2A135PubTator's text mininghttps://conductscience.org/library/genes/135NCBI Gene
AGT183PubTator's text mininghttps://conductscience.org/library/genes/183NCBI Gene
ANPEP290PubTator's text mininghttps://conductscience.org/library/genes/290NCBI Gene
ARG1383PubTator's text mininghttps://conductscience.org/library/genes/383NCBI Gene
ATXN16,310PubTator's text mininghttps://conductscience.org/library/genes/6310NCBI Gene
BATF355,509PubTator's text mininghttps://conductscience.org/library/genes/55509NCBI Gene
BST2684PubTator's text mininghttps://conductscience.org/library/genes/684NCBI Gene
BTLA151,888PubTator's text mininghttps://conductscience.org/library/genes/151888NCBI Gene
C1QA712PubTator's text mininghttps://conductscience.org/library/genes/712NCBI Gene
C3AR1719PubTator's text mininghttps://conductscience.org/library/genes/719NCBI Gene

1 to 10 of 170

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Drugs0

The drugs whose trials, in the Pipelines release, list the paper.

None in this release.

Data0

The data bank entries PubMed's record names. Trial numbers are under Trials.

None in this release.

Data dates

The date of each source this release read.

PubMed
2026-11-06
PubMed
iCite
2026-11-05
iCite
PMC's ID file
2026-11-05
PMC's ID file
NIH RePORTER's grant and paper links
2026-11-01
NIH RePORTER's grant and paper links
Trials
2026-11-12
Gene search
2026-11-11
Pipelines
2026-09-18

Sources 11

  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • HGNCCC0
  • iCiteCC BY 4.0
  • NCBI GenePublic domain (US government)
  • NIH RePORTER's grant and paper linksPublic domain
  • Open TargetsCC0 1.0
  • PMC's ID filePublic domain (US government)
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • HGNCCC0: https://www.genenames.org/about/license/
  • iCiteCC BY 4.0
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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