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Paper · 34002083

Pancreatic cancer epidemiology: understanding the role of lifestyle and inherited risk factors.

Klein AP. Nat Rev Gastroenterol Hepatol, 2021. Cited by 1,054 papers, by iCite.

11 sourcespapers-2026-11-12-0.1.0

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ConductScience Library. Pancreatic cancer epidemiology: understanding the role of lifestyle and inherited risk factors. Papers, record 34002083. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/34002083

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Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title
Pancreatic cancer epidemiology: understanding the role of lifestyle and inherited risk factors.
PubMed
Journal
Nat Rev Gastroenterol Hepatol
PubMed
Year
2021
PubMed
Publication types
Journal Article, Research Support, N.I.H., Extramural, Research Support, Non-U.S. Gov't, Review
PubMed
Citations, by iCite
1,054
iCite
Relative citation ratio, by iCite
65.7
iCite
Revised in PubMed
2022-10-30
PubMed

Authors1

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

OrderAuthorForenameKindORCID iD
1Klein APAlison Phttps://orcid.org/0000-0003-2737-8399

Source PubMed

Topics7

NLM's MeSH indexing of the paper, its major topics first.

MeSH termMajor
Pancreatic NeoplasmsMajor topic
Comorbidity
Early Detection of Cancer
Genetic Predisposition to Disease
Humans
Life Style
Risk Factors

Source PubMed

Grants4

Each grant PubMed's record writes, matched to the NIH project NIH's grant and paper links name for this paper, and each of those links the record does not write.

Grant, as the record writes itAgencyCountryNIH projectStated bySource
P30 CA006973NCI NIH HHSUnited StatesP30CA006973PubMed and NIHNIH RePORTER
P50 CA062924NCI NIH HHSUnited StatesP50CA062924PubMed and NIHNIH RePORTER
R01 CA154823NCI NIH HHSUnited StatesR01CA154823PubMed and NIHNIH RePORTER
U01 CA247283NCI NIH HHSUnited StatesU01CA247283PubMed and NIHNIH RePORTER

Trials2

The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.

TrialTitleThe trial lists it asNamed in the paper's recordSource
NCT06638866AI-powered Early Detection for Pancreatic Cancer Via Non-contrast CT in Opportunistic Screening CohortBackgroundClinicalTrials.gov
NCT07173374Stereotactic Centralized Ablative Radiotherapy for Locally Advanced Pancreatic Cancer: A Single-Arm Phase I Safety and Feasibility StudyBackgroundClinicalTrials.gov

Comments and corrections0

PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.

None in this release.

References140

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

OrderPMIDTitleJournalYearIn PapersSource
131,648,975Pancreatic cancer: a growing burden.Lancet Gastroenterol Hepatol2019https://conductscience.org/library/papers/31648975PubMed
230,350,310Estimating the global cancer incidence and mortality in 2018: GLOBOCAN sources and methods.Int J Cancer2019https://conductscience.org/library/papers/30350310PubMed
330,207,593Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries.CA Cancer J Clin2018https://conductscience.org/library/papers/30207593PubMed
412,500,045Why do Black Americans have a higher risk of pancreatic cancer than White Americans?Epidemiology2003https://conductscience.org/library/papers/12500045PubMed
531,912,902Cancer statistics, 2020.CA Cancer J Clin2020https://conductscience.org/library/papers/31912902PubMed
616,514,137Cancer statistics, 2006.CA Cancer J Clin2006https://conductscience.org/library/papers/16514137PubMed
723,472,8292564 resected periampullary adenocarcinomas at a single institution: trends over three decades.HPB (Oxford)2014https://conductscience.org/library/papers/23472829PubMed
831,958,122Recent Trends in the Incidence and Survival of Stage 1A Pancreatic Cancer: A Surveillance, Epidemiology, and End Results Analysis.J Natl Cancer Inst2020https://conductscience.org/library/papers/31958122PubMed
923,187,835Pathology and molecular genetics of pancreatic neoplasms.Cancer J2012https://conductscience.org/library/papers/23187835PubMed
1018,193,270Tobacco and the risk of pancreatic cancer: a review and meta-analysis.Langenbecks Arch Surg2008https://conductscience.org/library/papers/18193270PubMed

1 to 10 of 140

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Cited by811

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 1,054 citations.

PMIDTitleJournalYearIn PapersSource
42,958,510Association between a combined lifestyle exposure index and age at pancreatic cancer diagnosis: a hospital-based retrospective study.BMC Gastroenterol2026https://conductscience.org/library/papers/42958510PubMed
42,935,641Global and registry-based patterns of pancreatic cancer: GLOBOCAN 2020, CI5plus trends (2000-2017), and demographic projections to 2040.Front Oncol2026https://conductscience.org/library/papers/42935641PubMed
42,934,594Burdens of pancreatic cancer from 1990 to 2021 and projection to 2050 in China: findings from the 2021 global burden of disease study.BMC Cancer2026https://conductscience.org/library/papers/42934594PubMed
42,877,528Strategy for early diagnosis of pancreatic cancer.Front Gastroenterol (Lausanne)2026https://conductscience.org/library/papers/42877528PubMed
42,837,076The projected rise of pancreatic cancer mortality in Italy: forecasts until 2035.Updates Surg2026https://conductscience.org/library/papers/42837076PubMed
42,814,531Multi-Omics and Computational Pharmacology Approach With Experimental Validation Reveals the Antiproliferative Activity of Sophoricoside Against Pancreatic Cancer.Chem Biodivers2026https://conductscience.org/library/papers/42814531PubMed
42,796,338Pretreatment CONUT Score and Overall Survival in Patients with Metastatic Pancreatic Adenocarcinoma Receiving First-Line Chemotherapy: A Retrospective Cohort Study.Medicina (Kaunas)2026https://conductscience.org/library/papers/42796338PubMed
42,780,696Quality and reliability of pancreaticoduodenectomy-related videos on TikTok, Bilibili, and YouTube: a cross-sectional content analysis.Front Surg2026https://conductscience.org/library/papers/42780696PubMed
42,766,065Personalized neoantigen mRNA vaccines for pancreatic cancer: the role of lipid nanoparticle delivery systems.Daru2026https://conductscience.org/library/papers/42766065PubMed
42,763,477ZO-2 blocks the localization of PGAM5 protein to the mitochondrial membrane and suppresses pancreatic cancer malignancy through metabolic reprogramming.Genes Dis2027https://conductscience.org/library/papers/42763477PubMed

1 to 10 of 811

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Genes34

The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.

GeneNCBI Gene IDLinked byIn GenesSource
ABO28PubTator's text mininghttps://conductscience.org/library/genes/28NCBI Gene
ATM472PubTator's text mininghttps://conductscience.org/library/genes/472NCBI Gene
BCAR19,564PubTator's text mininghttps://conductscience.org/library/genes/9564NCBI Gene
BRCA1672PubTator's text mininghttps://conductscience.org/library/genes/672NCBI Gene
BRCA2675PubTator's text mininghttps://conductscience.org/library/genes/675NCBI Gene
CDKN2A1,029PubTator's text mininghttps://conductscience.org/library/genes/1029NCBI Gene
CFTR1,080PubTator's text mininghttps://conductscience.org/library/genes/1080NCBI Gene
CLPTM1L81,037PubTator's text mininghttps://conductscience.org/library/genes/81037NCBI Gene
CPA11,357PubTator's text mininghttps://conductscience.org/library/genes/1357NCBI Gene
CPB11,360PubTator's text mininghttps://conductscience.org/library/genes/1360NCBI Gene

1 to 10 of 34

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Drugs0

The drugs whose trials, in the Pipelines release, list the paper.

None in this release.

Data0

The data bank entries PubMed's record names. Trial numbers are under Trials.

None in this release.

Data dates

The date of each source this release read.

PubMed
2026-11-06
PubMed
iCite
2026-11-05
iCite
PMC's ID file
2026-11-05
PMC's ID file
NIH RePORTER's grant and paper links
2026-11-01
NIH RePORTER's grant and paper links
Trials
2026-11-12
Gene search
2026-11-11
Pipelines
2026-09-18

Sources 11

  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • HGNCCC0
  • iCiteCC BY 4.0
  • NCBI GenePublic domain (US government)
  • NIH RePORTER's grant and paper linksPublic domain
  • Open TargetsCC0 1.0
  • PMC's ID filePublic domain (US government)
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • HGNCCC0: https://www.genenames.org/about/license/
  • iCiteCC BY 4.0
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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