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Paper · 40211707

Brevilin A inhibits IL‑17A‑induced inflammation in psoriasis by modulating HSP 70.

Li CL and 8 others. Mol Med Rep, 2025. Cited by 2 papers, by iCite.

11 sourcespapers-2026-11-12-0.1.0

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ConductScience Library. Brevilin A inhibits IL‑17A‑induced inflammation in psoriasis by modulating HSP 70. Papers, record 40211707. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/40211707

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Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title
Brevilin A inhibits IL‑17A‑induced inflammation in psoriasis by modulating HSP 70.
PubMed
Journal
Mol Med Rep
PubMed
Year
2025
PubMed
Publication types
Journal Article
PubMed
Citations, by iCite
2
iCite
Revised in PubMed
2025-04-18
PubMed

Authors9

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

OrderAuthorForenameKindORCID iD
1Li CLChia-Ling
2Yeh KYKuei-Ying
3Huang WNWen-Nan
4Yen CYChung-Yang
5Wang KCKai-Chun
6Liao ECEn-Chih
7Chou TYTing-Yu
8Huang HSHung-Sen
9Yu SJSheng-Jie

Source PubMed

Topics14

NLM's MeSH indexing of the paper, its major topics first.

MeSH termMajor
PsoriasisMajor topic
Interleukin-17Major topic
HSP70 Heat-Shock ProteinsMajor topic
InflammationMajor topic
Animals
Humans
Mice
Cytokines
HaCaT Cells
Disease Models, Animal
Keratinocytes
Skin
Cell Line
Male

Source PubMed

Grants0

Each grant PubMed's record writes, matched to the NIH project NIH's grant and paper links name for this paper, and each of those links the record does not write.

None in this release.

Trials0

The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.

None in this release.

Comments and corrections0

PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.

None in this release.

References33

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

OrderPMIDTitleJournalYearIn PapersSource
116,834,562Stress protein expression kinetics.Annu Rev Biomed Eng2006https://conductscience.org/library/papers/16834562PubMed
227,696,208Structure-Based Drug Designing and Simulation Studies for Finding Novel Inhibitors of Heat Shock Protein (HSP70) as Suppressors for Psoriasis.Interdiscip Sci2018https://conductscience.org/library/papers/27696208PubMed
336,041,498Activation of TREM2 attenuates neuroinflammation via PI3K/Akt signaling pathway to improve postoperative cognitive dysfunction in mice.Neuropharmacology2022https://conductscience.org/library/papers/36041498PubMed
411,533,664Heat-shock protein 70 antagonizes apoptosis-inducing factor.Nat Cell Biol2001https://conductscience.org/library/papers/11533664PubMed
521,283,720The Hsc/Hsp70 co-chaperone network controls antigen aggregation and presentation during maturation of professional antigen presenting cells.PLoS One2011https://conductscience.org/library/papers/21283720PubMed
637,686,332Inhibition of NLRP3 Inflammasome Activation by 3H-1,2-Dithiole-3-Thione: A Potential Therapeutic Approach for Psoriasis Treatment.Int J Mol Sci2023https://conductscience.org/library/papers/37686332PubMed
729,226,422Pathogenesis of psoriasis and development of treatment.J Dermatol2018https://conductscience.org/library/papers/29226422PubMed
836,009,046Heat Shock Protein 90 (Hsp90) and Hsp70 as Potential Therapeutic Targets in Autoimmune Skin Diseases.Biomolecules2022https://conductscience.org/library/papers/36009046PubMed
931,316,496TRAF Regulation of IL-17 Cytokine Signaling.Front Immunol2019https://conductscience.org/library/papers/31316496PubMed
1028,865,459Clinical efficacy and IL-17 targeting mechanism of Indigo naturalis as a topical agent in moderate psoriasis.BMC Complement Altern Med2017https://conductscience.org/library/papers/28865459PubMed

1 to 10 of 33

See all 33 references

Cited by3

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 2 citations.

PMIDTitleJournalYearIn PapersSource
42,154,435Heat Shock Proteins as Cancer Biomarkers: From Mechanism to Clinical Application.Mol Diagn Ther2026https://conductscience.org/library/papers/42154435PubMed
42,055,684Keratinocyte-specific STAT3 knockout attenuates imiquimod-induced psoriasiform phenotype in mice.Exp Anim2026https://conductscience.org/library/papers/42055684PubMed
41,466,423Brevilin A reverses colitis of inflammatory bowel disease via modulation of TNF-α signaling and microbiome dysregulation.Gut Pathog2025https://conductscience.org/library/papers/41466423PubMed

Genes5

The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.

GeneNCBI Gene IDLinked byIn GenesSource
CXCL83,576PubTator's text mininghttps://conductscience.org/library/genes/3576NCBI Gene
HSP90AA13,320PubTator's text mininghttps://conductscience.org/library/genes/3320NCBI Gene
HSPA43,308PubTator's text mininghttps://conductscience.org/library/genes/3308NCBI Gene
IL17A3,605PubTator's text mininghttps://conductscience.org/library/genes/3605NCBI Gene
IL63,569PubTator's text mininghttps://conductscience.org/library/genes/3569NCBI Gene

Drugs0

The drugs whose trials, in the Pipelines release, list the paper.

None in this release.

Data0

The data bank entries PubMed's record names. Trial numbers are under Trials.

None in this release.

Data dates

The date of each source this release read.

PubMed
2026-11-06
PubMed
iCite
2026-11-05
iCite
PMC's ID file
2026-11-05
PMC's ID file
NIH RePORTER's grant and paper links
2026-11-01
NIH RePORTER's grant and paper links
Trials
2026-11-12
Gene search
2026-11-11
Pipelines
2026-09-18

Sources 11

  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • HGNCCC0
  • iCiteCC BY 4.0
  • NCBI GenePublic domain (US government)
  • NIH RePORTER's grant and paper linksPublic domain
  • Open TargetsCC0 1.0
  • PMC's ID filePublic domain (US government)
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • HGNCCC0: https://www.genenames.org/about/license/
  • iCiteCC BY 4.0
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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