Paper · 41369412
Linking AIM2 Inflammasome Activation, Mitochondrial Dysfunction and Chronic Inflammation in Ankylosing Spondylitis.
Boengiu CA and 4 others. Cells, 2025. Cited by 7 papers, by iCite.
11 sourcespapers-2026-11-12-0.1.0
Cite this record
ConductScience Library. Linking AIM2 Inflammasome Activation, Mitochondrial Dysfunction and Chronic Inflammation in Ankylosing Spondylitis. Papers, record 41369412. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/41369412
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Paper
PubMed's record of the paper, with iCite's citation figures. No abstract is shown.
- Title
- Linking AIM2 Inflammasome Activation, Mitochondrial Dysfunction and Chronic Inflammation in Ankylosing Spondylitis.
- PubMed
Topics10
NLM's MeSH indexing of the paper, its major topics first.
| MeSH term | Major |
|---|---|
| Inflammasomes | Major topic |
| Spondylitis, Ankylosing | Major topic |
| Mitochondria | Major topic |
| Inflammation | Major topic |
| DNA-Binding Proteins | Major topic |
| Humans | |
| Animals | |
| Chronic Disease | |
| Mitophagy | |
| DNA, Mitochondrial |
Source PubMed
Grants0
Each grant PubMed's record writes, matched to the NIH project NIH's grant and paper links name for this paper, and each of those links the record does not write.
None in this release.
Trials0
The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.
None in this release.
Comments and corrections0
PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.
None in this release.
References120
The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.
| Order | PMID | Title | Journal | Year | In Papers | Source |
|---|---|---|---|---|---|---|
| 1 | 32,202,065 | Mitochondrial DNA in inflammation and immunity. | EMBO Rep | 2020 | https://conductscience.org/library/papers/32202065 | PubMed |
| 2 | 39,063,056 | Environmental and Genetic Determinants of Ankylosing Spondylitis. | Int J Mol Sci | 2024 | https://conductscience.org/library/papers/39063056 | PubMed |
| 3 | 35,182,270 | Diagnostic delay in axial spondyloarthritis: a systematic review. | Clin Rheumatol | 2022 | https://conductscience.org/library/papers/35182270 | PubMed |
| 4 | 32,429,264 | Inflammatory and Oxidative Stress Markers-Mirror Tools in Rheumatoid Arthritis. | Biomedicines | 2020 | https://conductscience.org/library/papers/32429264 | PubMed |
| 5 | 1,574,116 | A novel heterodimeric cysteine protease is required for interleukin-1 beta processing in monocytes. | Nature | 1992 | https://conductscience.org/library/papers/1574116 | PubMed |
| 6 | 28,879,051 | Targeting danger molecules in tendinopathy: the HMGB1/TLR4 axis. | RMD Open | 2017 | https://conductscience.org/library/papers/28879051 | PubMed |
| 7 | 34,593,604 | DNA Repair Inhibition Leads to Active Export of Repetitive Sequences to the Cytoplasm Triggering an Inflammatory Response. | J Neurosci | 2021 | https://conductscience.org/library/papers/34593604 | PubMed |
| 8 | 39,300,122 | Pyroptosis in health and disease: mechanisms, regulation and clinical perspective. | Signal Transduct Target Ther | 2024 | https://conductscience.org/library/papers/39300122 | PubMed |
| 9 | 34,618,347 | A Pooled Analysis Reporting the Efficacy and Safety of Secukinumab in Male and Female Patients with Ankylosing Spondylitis. | Rheumatol Ther | 2021 | https://conductscience.org/library/papers/34618347 | PubMed |
| 10 | 37,708,431 | Molecular Activation of NLRP3 Inflammasome by Particles and Crystals: A Continuing Challenge of Immunology and Toxicology. | Annu Rev Pharmacol Toxicol | 2024 | https://conductscience.org/library/papers/37708431 | PubMed |
1 to 10 of 120
See all 120 referencesCited by4
The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 7 citations.
| PMID | Title | Journal | Year | In Papers | Source |
|---|---|---|---|---|---|
| 42,947,142 | Mitochondria as the core regulator of cell death: from classical programmed cell death to the novel mitoxyperiosis pathway. | J Transl Med | 2026 | https://conductscience.org/library/papers/42947142 | PubMed |
| 42,412,246 | Endosymbiotic theory of aging revisited: Age-related leakage of mitochondrial dsDNA/RNA stimulates cytosolic nucleic acid sensors which remodel the immune network and promote the aging process. | Biogerontology | 2026 | https://conductscience.org/library/papers/42412246 | PubMed |
| 42,193,171 | Oxidative-Stress-Associated Molecular Signatures in Immune-Mediated Diseases: A Systematic Review Integrating Machine Learning and Systems Biology Approaches. | Antioxidants (Basel) | 2026 | https://conductscience.org/library/papers/42193171 | PubMed |
| 42,037,994 | Mechanistic insights and challenges in mitochondrial regulation of macrophage polarization and inflammatory responses. | Front Physiol | 2026 | https://conductscience.org/library/papers/42037994 | PubMed |
Genes4
The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.
| Gene | NCBI Gene ID | Linked by | In Genes | Source |
|---|---|---|---|---|
| AIM2 | 9,447 | PubTator's text mining | https://conductscience.org/library/genes/9447 | NCBI Gene |
| IL17A | 3,605 | PubTator's text mining | https://conductscience.org/library/genes/3605 | NCBI Gene |
| NLRP3 | 114,548 | PubTator's text mining | https://conductscience.org/library/genes/114548 | NCBI Gene |
| TNF | 7,124 | PubTator's text mining | https://conductscience.org/library/genes/7124 | NCBI Gene |
Drugs0
The drugs whose trials, in the Pipelines release, list the paper.
None in this release.
Data0
The data bank entries PubMed's record names. Trial numbers are under Trials.
None in this release.
Data dates
The date of each source this release read.
- Trials
- 2026-11-12
- Gene search
- 2026-11-11
- Pipelines
- 2026-09-18
Sources 11
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- HGNCCC0
- iCiteCC BY 4.0
- NCBI GenePublic domain (US government)
- NIH RePORTER's grant and paper linksPublic domain
- Open TargetsCC0 1.0
- PMC's ID filePublic domain (US government)
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- HGNCCC0: https://www.genenames.org/about/license/
- iCiteCC BY 4.0
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
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