Paper · 32202065

Mitochondrial DNA in inflammation and immunity.

Riley JS and 1 other. EMBO Rep, 2020. Cited by 738 papers, by iCite.

11 sourcespapers-2026-11-12-0.1.0

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ConductScience Library. Mitochondrial DNA in inflammation and immunity. Papers, record 32202065. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/32202065

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Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title: Mitochondrial DNA in inflammation and immunity.; PubMed
Journal: EMBO Rep; PubMed
Year: 2020; PubMed
Publication types: Journal Article, Research Support, Non-U.S. Gov't, Review; PubMed
PubMed: https://pubmed.ncbi.nlm.nih.gov/32202065/; PubMed
DOI: https://doi.org/10.15252/embr.201949799; PubMed
PMC: https://pmc.ncbi.nlm.nih.gov/articles/PMC7132203/; PubMed
The journal: https://conductscience.org/library/journal-index/100963049; PubMed
Citations, by iCite: 738; iCite
Relative citation ratio, by iCite: 35; iCite
Revised in PubMed: 2021-04-27; PubMed

Authors2

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

Order	Author	Forename	Kind	ORCID iD
1	Riley JS	Joel S		https://orcid.org/0000-0001-9170-5716
2	Tait SW	Stephen Wg		https://orcid.org/0000-0001-7697-132X

Source PubMed

Topics6

NLM's MeSH indexing of the paper, its major topics first.

MeSH term	Major
DNA, Mitochondrial	Major topic
Mitochondria	Major topic
Humans
Immunity, Innate
Inflammation
Receptors, Pattern Recognition

Source PubMed

Grants2

Each grant PubMed's record writes, matched to the NIH project NIH's grant and paper links name for this paper, and each of those links the record does not write.

Grant, as the record writes it	Agency	Country	NIH project	Stated by
	Cancer Research UK	United Kingdom		PubMed
	Prostate Cancer UK	United Kingdom		PubMed

Source PubMed

Trials0

The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.

None in this release.

Comments and corrections0

PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.

None in this release.

References207

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

Order	PMID	Title	Journal	Year	In Papers	Source
1	31,808,743	Tight nuclear tethering of cGAS is essential for preventing autoreactivity.	Elife	2019	https://conductscience.org/library/papers/31808743	PubMed
2	26,919,428	NF-κB Restricts Inflammasome Activation via Elimination of Damaged Mitochondria.	Cell	2016	https://conductscience.org/library/papers/26919428	PubMed
3	32,202,065	Mitochondrial DNA in inflammation and immunity.	EMBO Rep	2020	https://conductscience.org/library/papers/32202065	PubMed
4	16,111,635	Suppression of RNA recognition by Toll-like receptors: the impact of nucleoside modification and the evolutionary origin of RNA.	Immunity	2005	https://conductscience.org/library/papers/16111635	PubMed
5	23,804,556	The control region of mitochondrial DNA shows an unusual CpG and non-CpG methylation pattern.	DNA Res	2013	https://conductscience.org/library/papers/23804556	PubMed
6	30,811,988	The N-Terminal Domain of cGAS Determines Preferential Association with Centromeric DNA and Innate Immune Activation in the Nucleus.	Cell Rep	2019	https://conductscience.org/library/papers/30811988	PubMed
7	27,071,149	Mechanisms of mitophagy: putting the powerhouse into the doghouse.	Biol Chem	2016	https://conductscience.org/library/papers/27071149	PubMed
8	17,450,150	The role of autophagy in cardiomyocytes in the basal state and in response to hemodynamic stress.	Nat Med	2007	https://conductscience.org/library/papers/17450150	PubMed
9	30,049,712	Mitochondrial inner membrane permeabilisation enables mtDNA release during apoptosis.	EMBO J	2018	https://conductscience.org/library/papers/30049712	PubMed
10	25,128,442	Mitochondrial DNA neutrophil extracellular traps are formed after trauma and subsequent surgery.	J Crit Care	2014	https://conductscience.org/library/papers/25128442	PubMed

1 to 10 of 207

See all 207 references

Cited by535

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 738 citations.

PMID	Title	Journal	Year	In Papers	Source
42,973,938	Bidirectional mitochondrial transfer in the osteoimmune microenvironment: mechanisms and therapeutic perspectives.	Front Endocrinol (Lausanne)	2026	https://conductscience.org/library/papers/42973938	PubMed
42,973,590	Conserved and particle-specific mitochondrial stress responses drive immunotoxicity of ultrafine particulate matter, black carbon, and polystyrene nanoplastics.	Front Immunol	2026	https://conductscience.org/library/papers/42973590	PubMed
42,957,672	IAP antagonist tolinapant (ASTX660) in combination with pembrolizumab in advanced solid tumors: a phase I trial.	Nat Commun	2026	https://conductscience.org/library/papers/42957672	PubMed
42,939,680	The Nuclear Damage-Response Code of Cutaneous Wound Repair: Mechanotransduction, cGAS-STING, Senescence, and Regenerative Interfaces.	Biomolecules	2026	https://conductscience.org/library/papers/42939680	PubMed
42,929,812	BAX, VDAC, Gasdermin, and Permeability Transition Pores in Inflammatory Mitochondrial DNA Release: Is This the "Hole" Story?	Cells	2026	https://conductscience.org/library/papers/42929812	PubMed
42,919,136	The role of the mitochondrial injury-mediated oxidative stress-sterile inflammation axis in varicocele-induced infertility: a narrative review.	Basic Clin Androl	2026	https://conductscience.org/library/papers/42919136	PubMed
42,899,200	Mitochondrial Metabolic Reprogramming in Macrophages: A Key Driver of Rheumatoid Arthritis.	J Inflamm Res	2026	https://conductscience.org/library/papers/42899200	PubMed
42,884,017	Organelle-Selective Autophagy in Cancer Immunotherapy: Mitophagy and Nucleophagy-Related Nuclear Quality Control as Regulators of Tumor-Immune Interactions.	Int J Mol Sci	2026	https://conductscience.org/library/papers/42884017	PubMed
42,875,857	Mitochondrial Quality Control in Degenerative Musculoskeletal Diseases: Signaling Networks and Therapeutic Landscapes.	Adv Sci (Weinh)	2026	https://conductscience.org/library/papers/42875857	PubMed
42,866,448	The role of metabolic crosstalk between Intestinal epithelial cells and immune cells in inflammatory bowel disease and targeting strategies.	Front Immunol	2026	https://conductscience.org/library/papers/42866448	PubMed

1 to 10 of 535

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Genes20

The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.

Gene	NCBI Gene ID	Linked by	In Genes	Source
BAK1	578	PubTator's text mining	https://conductscience.org/library/genes/578	NCBI Gene
BAX	581	PubTator's text mining	https://conductscience.org/library/genes/581	NCBI Gene
CGAS	115,004	PubTator's text mining	https://conductscience.org/library/genes/115004	NCBI Gene
CTSG	1,511	PubTator's text mining	https://conductscience.org/library/genes/1511	NCBI Gene
CXCL8	3,576	PubTator's text mining	https://conductscience.org/library/genes/3576	NCBI Gene
HMGB1	3,146	PubTator's text mining	https://conductscience.org/library/genes/3146	NCBI Gene
IFNA1	3,439	PubTator's text mining	https://conductscience.org/library/genes/3439	NCBI Gene
IFNAR1	3,454	PubTator's text mining	https://conductscience.org/library/genes/3454	NCBI Gene
IFNG	3,458	PubTator's text mining	https://conductscience.org/library/genes/3458	NCBI Gene
IL6	3,569	PubTator's text mining	https://conductscience.org/library/genes/3569	NCBI Gene

1 to 10 of 20

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Drugs0

The drugs whose trials, in the Pipelines release, list the paper.

None in this release.

Data0

The data bank entries PubMed's record names. Trial numbers are under Trials.

None in this release.

Data dates

The date of each source this release read.

PubMed: 2026-11-06; PubMed
iCite: 2026-11-05; iCite
PMC's ID file: 2026-11-05; PMC's ID file
NIH RePORTER's grant and paper links: 2026-11-01; NIH RePORTER's grant and paper links
Trials: 2026-11-12
Gene search: 2026-11-11
Pipelines: 2026-09-18

Sources 11

ChEMBL, through Open TargetsCC BY-SA 3.0
ClinicalTrials.govNo license stated
HGNCCC0
iCiteCC BY 4.0
NCBI GenePublic domain (US government)
NIH RePORTER's grant and paper linksPublic domain
Open TargetsCC0 1.0
PMC's ID filePublic domain (US government)
PubMedNLM's terms
PubTator 3Public domain
UniProtCC BY 4.0

Each source's terms

ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
ClinicalTrials.govnone stated
HGNCCC0: https://www.genenames.org/about/license/
iCiteCC BY 4.0
NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
PubMedNLM's terms
PubTator 3Public domain
UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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