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Paper59937

Alpha 2-macroglobulin and antithrombin-heparin cofactor: modulators of hemostatic and inflammatory reactions. Alpha 2-macroglobulin.

Harpel PC and 1 other. Prog Hemost Thromb, 1976. Cited by 50 papers, by iCite.

11 sourcespapers-2026-11-12-0.1.0

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ConductScience Library. Alpha 2-macroglobulin and antithrombin-heparin cofactor: modulators of hemostatic and inflammatory reactions. Alpha 2-macroglobulin. Papers, record 59937. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/59937

Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title
Alpha 2-macroglobulin and antithrombin-heparin cofactor: modulators of hemostatic and inflammatory reactions. Alpha 2-macroglobulin.
PubMed
Journal
Prog Hemost Thromb
PubMed
Year
1976
PubMed
Publication types
Journal Article, Research Support, U.S. Gov't, P.H.S., Review
PubMed
Citations, by iCite
50
iCite
Relative citation ratio, by iCite
1.86
iCite
Revised in PubMed
2009-11-19
PubMed

Authors2

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

OrderAuthorForenameKindORCID iD
1Harpel PCP C
2Rosenberg RDR D

Source PubMed

Topics19

NLM's MeSH indexing of the paper, its major topics first.

MeSH termMajor
alpha 1-AntitrypsinMajor topic
alpha-MacroglobulinsMajor topic
Amino Acid Sequence
Antithrombin III
Antithrombins
Body Fluids
Carbohydrates
Chymotrypsin
Complement C1 Inactivator Proteins
Electrophoresis, Polyacrylamide Gel
Fibrinolysin
Humans
Kallikreins
Lymphocytes
Molecular Weight
Polymorphism, Genetic
Receptors, Antigen, B-Cell
Thrombin
Trypsin

Source PubMed

Cited by19

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 50 citations.

PMIDTitleJournalYearIn PapersSource
32,257,894Tracking acute phase protein response during acute and chronic Toxoplasma gondii infection.Lab Anim Res2019https://conductscience.org/library/papers/32257894PubMed
30,174,527Antimicrobial, anticoagulant, and cytotoxic evaluation of multidrug resistance of new 1,4-dihydropyridine derivatives.Saudi J Biol Sci2018https://conductscience.org/library/papers/30174527PubMed
17,526,957Plasma protein variations in hemophiliacs receiving factor replacement therapy.Indian J Pediatr2007https://conductscience.org/library/papers/17526957PubMed
6,993,082Clinical pharmacokinetics of heparin.Clin Pharmacokinet1980https://conductscience.org/library/papers/6993082PubMed
6,725,600Antithrombin III metabolism in patients with liver disease.J Clin Pathol1984https://conductscience.org/library/papers/6725600PubMed
6,222,069Protection of factor Xa from neutralization by the heparin-antithrombin complex.J Clin Invest1983https://conductscience.org/library/papers/6222069PubMed
6,204,637Covalent binding of proteinases in their reaction with alpha 2-macroglobulin.Biochem J1980https://conductscience.org/library/papers/6204637PubMed
6,198,737The beta-Cys-gamma-Glu thiolester bond in human C3, C4, and alpha 2-macroglobulin.Springer Semin Immunopathol1983https://conductscience.org/library/papers/6198737PubMed
6,196,377Regulation of factor Xa in vitro in human and mouse plasma and in vivo in mouse. Role of the endothelium and plasma proteinase inhibitors.J Clin Invest1983https://conductscience.org/library/papers/6196377PubMed
6,172,907The use of pathophysiological reactions to assess the efficacy of the immune response to Babesia bovis in cattle.Z Parasitenkd1981https://conductscience.org/library/papers/6172907PubMed
6,166,634Alpha2-plasmin inhibitor and alpha2-macroglobulin-plasmin complexes in plasma. Quantitation by an enzyme-linked differential antibody immunosorbent assay.J Clin Invest1981https://conductscience.org/library/papers/6166634PubMed
6,158,195The irradiation of Babesia bovis. 1. The difference in pathogenicity between irradiated and non-irradiated populations.Z Parasitenkd1980https://conductscience.org/library/papers/6158195PubMed
6,085,504Profiles of acute-phase reactants and clinical significance of alpha 2-macroglobulin in acute hepatitis B.Inflammation1983https://conductscience.org/library/papers/6085504PubMed
4,020,324Cellular processing of bovine factors X and Xa by cultured bovine aortic endothelial cells.J Exp Med1985https://conductscience.org/library/papers/4020324PubMed
3,965,500Variability in purified dysfunctional C1(-)-inhibitor proteins from patients with hereditary angioneurotic edema. Functional and analytical gel studies.J Clin Invest1985https://conductscience.org/library/papers/3965500PubMed
2,476,904Increased alpha 2-macroglobulin in diabetes: a hyperglycemia related phenomenon associated with reduced antithrombin III activity.Acta Diabetol Lat1989https://conductscience.org/library/papers/2476904PubMed
345,780Macrophage proteases and rheumatic diseases: regulation of plasminogen activator by thymus-derived lymphocytes.Agents Actions1978https://conductscience.org/library/papers/345780PubMed
70,499Plasmin inhibitor interactions. The effectiveness of alpha2-plasmin inhibitor in the presence of alpha2-macroglobulin.J Exp Med1977https://conductscience.org/library/papers/70499PubMed
58,955alpha2-Macroglobulin on human vascular endothelium.J Exp Med1976https://conductscience.org/library/papers/58955PubMed

Genes2

The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.

GeneNCBI Gene IDLinked byIn GenesSource
A2M2PubTator's text mininghttps://conductscience.org/library/genes/2NCBI Gene
SERPINC1462PubTator's text mininghttps://conductscience.org/library/genes/462NCBI Gene

Data dates

The date of each source this release read.

PubMed
2026-11-06
PubMed
iCite
2026-11-05
iCite
PMC's ID file
2026-11-05
PMC's ID file
NIH RePORTER's grant and paper links
2026-11-01
NIH RePORTER's grant and paper links
Trials
2026-11-12
Gene search
2026-11-11
Pipelines
2026-09-18

None in this release

  • Grants
  • Trials
  • Comments and corrections
  • References
  • Drugs
  • Data

Sources 11

  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • HGNCCC0
  • iCiteCC BY 4.0
  • NCBI GenePublic domain (US government)
  • NIH RePORTER's grant and paper linksPublic domain
  • Open TargetsCC0 1.0
  • PMC's ID filePublic domain (US government)
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • HGNCCC0: https://www.genenames.org/about/license/
  • iCiteCC BY 4.0
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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