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Paper75939

In vivo effects of anti-Ia alloantisera. I. Elimination of specific suppression by in vivo administration of antisera specific for I-J controlled determinants.

Pierres M and 3 others. J Exp Med, 1978. Cited by 67 papers, by iCite.

11 sourcespapers-2026-11-12-0.1.0

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ConductScience Library. In vivo effects of anti-Ia alloantisera. I. Elimination of specific suppression by in vivo administration of antisera specific for I-J controlled determinants. Papers, record 75939. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/75939

Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title
In vivo effects of anti-Ia alloantisera. I. Elimination of specific suppression by in vivo administration of antisera specific for I-J controlled determinants.
PubMed
Journal
J Exp Med
PubMed
Year
1978
PubMed
Publication types
Journal Article, Research Support, U.S. Gov't, Non-P.H.S., Research Support, U.S. Gov't, P.H.S.
PubMed
Citations, by iCite
67
iCite
Relative citation ratio, by iCite
1.53
iCite
Revised in PubMed
2021-12-03
PubMed

Authors4

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

OrderAuthorForenameKindORCID iD
1Pierres MM
2Germain RNR N
3Dorf MEM E
4Benacerraf BB

Source PubMed

Topics14

NLM's MeSH indexing of the paper, its major topics first.

MeSH termMajor
Antibody FormationMajor topic
Genes, MHC Class IIMajor topic
Immunosuppression TherapyMajor topic
IsoantibodiesMajor topic
PeptidesMajor topic
T-LymphocytesMajor topic
Animals
Antigen-Antibody Reactions
Epitopes
Female
Immunization, Passive
Male
Mice
Mice, Inbred Strains

Source PubMed

References23

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

OrderPMIDTitleJournalYearIn PapersSource
11,080,181
Genetic control of immune responses in vitro. VI. Experimental conditions for the development of helper T-cell activity specific for the terpolymer L-glutamic aicd60-L-alanine30-L-tyrosine10 (GAT) in nonresponder mice.
J Exp Med1975https://conductscience.org/library/papers/1080181PubMed
21,082,894Regualtion of the immune response to tumor antigens. I. Immunosuppressor cells in tumor-bearing hosts.J Immunol1976https://conductscience.org/library/papers/1082894PubMed
31,084,407Genetic control of specific immune suppression. IV. Responsiveness to the random copolymer L-glutamic acid50-L-tyrosine50 induced in BALB/c mice by cyclophosphamide.J Exp Med1976https://conductscience.org/library/papers/1084407PubMed
41,085,324T-cell regulation of antibody responses: demonstration of allotype-specific helper T cells and their specific removal by suppressor T cells.J Exp Med1976https://conductscience.org/library/papers/1085324PubMed
51,085,338A new I subregion (I-J) marked by a locus (Ia-4) controlling surface determinants on suppressor T lymphocytes.J Exp Med1976https://conductscience.org/library/papers/1085338PubMed
61,085,339
Properties of the antigen-specific suppressive T-cell factor in the regulation of antibody response of the mouse. IV. Special subregion assignment of the gene(s) that codes for the suppressive T-cell factor in the H-2 histocompatibility complex.
J Exp Med1976https://conductscience.org/library/papers/1085339PubMed
71,104,746Genetic control of specific immune suppression. I. Experimental conditions for the stimulation of suppressor cells by the copolymer L-glutamic acid50-L-tyrosine50 (GT) in nonresponder BALB/c mice.J Exp Med1975https://conductscience.org/library/papers/1104746PubMed
81,117,258Augmentation of delayed-type hypersensitivity by doses of cyclophosphamide which do not affect antibody responses.J Exp Med1975https://conductscience.org/library/papers/1117258PubMed
91,118,728Inhibition of immune responses in vitro by specific antiserums to Ia antigens.Science1975https://conductscience.org/library/papers/1118728PubMed
101,194,855Genetic control of specific immune suppression. II. H-2-linked dominant genetic control of immune suppression by the random copolymer L-glutamic acid50-L-tyrosine50 (GT).J Exp Med1975https://conductscience.org/library/papers/1194855PubMed
111,254,955Regulation of the immune response to tumor antigens. II. The nature of immunosuppressor cells in tumor-bearing hosts.J Immunol1976https://conductscience.org/library/papers/1254955PubMed
12144,771The role of gene products of the I-J subregion in mixed lymphocyte reactions.J Exp Med1977https://conductscience.org/library/papers/144771PubMed
13302,186Suppressive and enhancing T-cell factors as I-region gene products: properties and the subregion assignment.Cold Spring Harb Symp Quant Biol1977https://conductscience.org/library/papers/302186PubMed
14302,317Immunosuppressive factor(s) specific for L-glutamic acid50-L-tyrosine50 (GT). III. Generation of suppressor T cells by a suppressive extract derived from GT-primed lymphoid cells.J Exp Med1977https://conductscience.org/library/papers/302317PubMed
15410,029Potentiation of a primary in vivo antibody response by alloantisera against gene products of the I region of the H-2 complex.Proc Natl Acad Sci U S A1977https://conductscience.org/library/papers/410029PubMed
164,137,682Genetic control of immune responses in vitro. V. Stimulation of suppressor T cells in nonresponder mice by the terpolymer L-glutamic acid 60-L-alanine 30-L-tyrosine 10 (GAT).J Exp Med1974https://conductscience.org/library/papers/4137682PubMed
174,539,650A cellular basis for genetically controlled immunologic unresponsiveness in mice: tolerance induction in T-cells.Proc Natl Acad Sci U S A1973https://conductscience.org/library/papers/4539650PubMed
184,610,076Immune responses in vitro. XI. Suppression of primary IgM and IgG plaque-forming cell responses in vitro by alloantisera against leukocyte alloantigens.J Exp Med1974https://conductscience.org/library/papers/4610076PubMed
194,934,502Immune responses in vitro. 3. Development of primary gamma-M, gamma-G, and gamma-A plaque-forming cell responses in mouse spleen cell cultures stimulated with heterologous erythrocytes.J Exp Med1971https://conductscience.org/library/papers/4934502PubMed
2062,014Effects of anti-Ia sera on mitogenic responses. III. Mapping the genes controlling the expression of Ia determinants on concanavalin A-reactive cells to the I-J subregion of the H-2 gene complex.J Exp Med1976https://conductscience.org/library/papers/62014PubMed

See all 23 references

Cited by16

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 67 citations.

PMIDTitleJournalYearIn PapersSource
10,603,394
Murine immune response to Neisseria meningitidis group C capsular polysaccharide: analysis of monoclonal antibodies generated in response to a thymus-independent antigen and a thymus-dependent toxoid conjugate vaccine.
Infect Immun2000https://conductscience.org/library/papers/10603394PubMed
9,784,556Murine immune responses to Neisseria meningitidis group C capsular polysaccharide and a thymus-dependent toxoid conjugate vaccine.Infect Immun1998https://conductscience.org/library/papers/9784556PubMed
6,970,642T lymphocyte subpopulations and Ia-positive T cells in patients with immunodeficiency.Clin Exp Immunol1980https://conductscience.org/library/papers/6970642PubMed
6,801,188Regulation of immune responses by I-J gene products. II. Presence of Both I-Jb and I-Jk suppressor factors in (nonsuppressor x nonsuppressor) F1 mice.J Exp Med1982https://conductscience.org/library/papers/6801188PubMed
6,795,302Regulation of immune responses by I-J gene products. I. Production and characterization of anti-I-J monoclonal antibodies.J Exp Med1981https://conductscience.org/library/papers/6795302PubMed
6,459,991
Genetic control of allogeneic interactions in the guinea-pig. IV. The specific elimination of MLC suppressor cells by the in vivo administration of antisera against a GPLA-B region-controlled determinant.
Immunology1982https://conductscience.org/library/papers/6459991PubMed
6,455,666Functional clonal deletion in immunological tolerance to major histocompatibility complex antigens.Proc Natl Acad Sci U S A1981https://conductscience.org/library/papers/6455666PubMed
6,444,306Studies of T- and B-cell interactions in adult patients with combined immunodeficiency.J Clin Invest1980https://conductscience.org/library/papers/6444306PubMed
6,293,112Regulation of the immune response to antigens on the malignant cell surface.Springer Semin Immunopathol1982https://conductscience.org/library/papers/6293112PubMed
6,101,117H-2-mediated resistance to an ecotropic type C retrovirus: localization of controlling genes and ontogenic studies of resistance.Immunogenetics1980https://conductscience.org/library/papers/6101117PubMed
3,161,079A role for suppressor T cells in induction of self-tolerance.Proc Natl Acad Sci U S A1985https://conductscience.org/library/papers/3161079PubMed
2,968,305Suppressor T cells, antigen-presenting cells and the role of I-J restriction in oral tolerance to ovalbumin.Immunology1988https://conductscience.org/library/papers/2968305PubMed
2,427,101Presence of I-region gene products on the cells and their products of the dengue virus-induced suppressor pathway.Br J Exp Pathol1986https://conductscience.org/library/papers/2427101PubMed
381,173Immunosuppressive ALS. II. Antibody to Ia antigens in heterologous anti-lymphocyte serum.Immunology1979https://conductscience.org/library/papers/381173PubMed
307,250
Regulation of antibody heterogeneity by suppressor T cells: diminishing suppressor T cell activity increases the number of dinitrophenyl clones in mice immunized with dinitrophenyl-poly(Glu,Lys,Phe) or dinitrophenyl-poly(Glu,Lys,Ala).
Proc Natl Acad Sci U S A1978https://conductscience.org/library/papers/307250PubMed
102,725The involvement of suppressor T cells in Ir gene regulation of secondary antibody responses of primed (responder X nonresponder)F1 mice to macrophage-bound L-glutamic acid60-L-alanine30-L-tyrosine.J Exp Med1978https://conductscience.org/library/papers/102725PubMed

Data dates

The date of each source this release read.

PubMed
2026-11-06
PubMed
iCite
2026-11-05
iCite
PMC's ID file
2026-11-05
PMC's ID file
NIH RePORTER's grant and paper links
2026-11-01
NIH RePORTER's grant and paper links
Trials
2026-11-12
Gene search
2026-11-11
Pipelines
2026-09-18

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  • ClinicalTrials.govNo license stated
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  • iCiteCC BY 4.0
  • NCBI GenePublic domain (US government)
  • NIH RePORTER's grant and paper linksPublic domain
  • Open TargetsCC0 1.0
  • PMC's ID filePublic domain (US government)
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • HGNCCC0: https://www.genenames.org/about/license/
  • iCiteCC BY 4.0
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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