ConductScience.org, home
Papers
API referenceFor AI assistants

Paper102725

The involvement of suppressor T cells in Ir gene regulation of secondary antibody responses of primed (responder X nonresponder)F1 mice to macrophage-bound L-glutamic acid60-L-alanine30-L-tyrosine.

Germain RN and 1 other. J Exp Med, 1978. Cited by 19 papers, by iCite.

11 sourcespapers-2026-11-12-0.1.0

Download JSON
Cite this record

ConductScience Library. The involvement of suppressor T cells in Ir gene regulation of secondary antibody responses of primed (responder X nonresponder)F1 mice to macrophage-bound L-glutamic acid60-L-alanine30-L-tyrosine. Papers, record 102725. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/102725

Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title
The involvement of suppressor T cells in Ir gene regulation of secondary antibody responses of primed (responder X nonresponder)F1 mice to macrophage-bound L-glutamic acid60-L-alanine30-L-tyrosine.
PubMed
Journal
J Exp Med
PubMed
Year
1978
PubMed
Publication types
Journal Article
PubMed
Citations, by iCite
19
iCite
Relative citation ratio, by iCite
0.5
iCite
Revised in PubMed
2021-12-03
PubMed

Authors2

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

OrderAuthorForenameKindORCID iD
1Germain RNR N
2Benacerraf BB

Source PubMed

Topics14

NLM's MeSH indexing of the paper, its major topics first.

MeSH termMajor
Antibody FormationMajor topic
Genes, MHC Class IIMajor topic
Immunologic MemoryMajor topic
Immunosuppression TherapyMajor topic
MacrophagesMajor topic
T-LymphocytesMajor topic
Alanine
Animals
Cyclophosphamide
Glutamates
Mice
Mice, Inbred Strains
Peptides
Tyrosine

Source PubMed

References28

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

OrderPMIDTitleJournalYearIn PapersSource
11,084,407Genetic control of specific immune suppression. IV. Responsiveness to the random copolymer L-glutamic acid50-L-tyrosine50 induced in BALB/c mice by cyclophosphamide.J Exp Med1976https://conductscience.org/library/papers/1084407PubMed
21,080,181
Genetic control of immune responses in vitro. VI. Experimental conditions for the development of helper T-cell activity specific for the terpolymer L-glutamic aicd60-L-alanine30-L-tyrosine10 (GAT) in nonresponder mice.
J Exp Med1975https://conductscience.org/library/papers/1080181PubMed
3112,037Interaction between antigen-presenting cells and primed T lymphocytes: an assessment of Ir gene expression in the antigen-presenting cell.Immunol Rev1978https://conductscience.org/library/papers/112037PubMed
416,073,428Determinant selection is a macrophage dependent immune response gene function.Nature1977https://conductscience.org/library/papers/16073428PubMed
5300,776
Immunosuppressive factor(s) extracted from lymphoid cells of nonresponder mice primed with L-glutamic acid60-L-alanine30-L-tyrosine10 (GAT) II. Cellular source and effect on responder and nonresponder mice.
J Exp Med1977https://conductscience.org/library/papers/300776PubMed
6302,177Genetic restriction of macrophage-lymphocyte interactions in secondary antibody responses in vitro.Cold Spring Harb Symp Quant Biol1977https://conductscience.org/library/papers/302177PubMed
7306,405Immunoregulatory circuits among T-cell sets. I. T-helper cells induce other T-cell sets to exert feedback inhibition.J Exp Med1978https://conductscience.org/library/papers/306405PubMed
8306,406Immunoregulatory circuits among T-cell sets. II. Physiologic role of feedback inhibition in vivo: absence in NZB mice.J Exp Med1978https://conductscience.org/library/papers/306406PubMed
9410,029Potentiation of a primary in vivo antibody response by alloantisera against gene products of the I region of the H-2 complex.Proc Natl Acad Sci U S A1977https://conductscience.org/library/papers/410029PubMed
10411,879Secondary antibody responses in vitro to L-glutamic acid60-L-alanine30-L-tyrosine10 (GAT) by (responder X nonresponder)F1 spleen cells stimulated by parental GAT-macrophages.J Exp Med1977https://conductscience.org/library/papers/411879PubMed
114,126,766
Genetic control of immune responses in vitro. I. Development of primary and secondary plaque-forming cell responses to the random terpolymer 1-glutamic acid 60-1-alanine30-1-tyrosine10 (GAT) by mouse spleen cells in vitro.
J Exp Med1973https://conductscience.org/library/papers/4126766PubMed
124,126,767
Genetic control of immune responses in vitro. II. Cellular requirements for the development of primary plaque-forming cell responses to the random terpolymer 1-glutamic acid 60-1-alanine30-1-tyrosine10 (GAT) by mouse spleen cells in vitro.
J Exp Med1973https://conductscience.org/library/papers/4126767PubMed
134,137,682Genetic control of immune responses in vitro. V. Stimulation of suppressor T cells in nonresponder mice by the terpolymer L-glutamic acid 60-L-alanine 30-L-tyrosine 10 (GAT).J Exp Med1974https://conductscience.org/library/papers/4137682PubMed
14415,110Two distinct types of helper T cells involved in the secondary antibody response: independent and synergistic effects of Ia- and Ia+ helper T cells.J Exp Med1978https://conductscience.org/library/papers/415110PubMed
1555,436Immunosuppressive factor(s) extracted from lymphoid cells of nonresponder mice primed with L-glutamic acid60-L-alanine30-L-tyrosine10 (GAT).J Immunol1976https://conductscience.org/library/papers/55436PubMed
1661,101The function of macrophages in T-lymphocyte antigen recognition.Contemp Top Immunobiol1976https://conductscience.org/library/papers/61101PubMed
1761,991Coexistence of helper and suppressor activities in carrier-primed spleen cells.J Immunol1976https://conductscience.org/library/papers/61991PubMed
1863,533Genetic control of the immune response to staphylococcal nuclease. IV. H-2-linked control of the relative proportions of antibodies produced to different determinants of native nuclease.J Exp Med1977https://conductscience.org/library/papers/63533PubMed
1967,171
Immunosuppressive factor(s) extracted from lymphoid cells of nonresponder mice primed with L-glutamic acid60-L-alanine30-L-tyrosine10 (GAT) III. Immunochemical properties of the GAT-specific suppressive factor.
J Exp Med1977https://conductscience.org/library/papers/67171PubMed
2075,167Different functional specificity repertoires for suppressor and helper T cells.Immunol Rev1978https://conductscience.org/library/papers/75167PubMed

See all 28 references

Cited by2

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 19 citations.

PMIDTitleJournalYearIn PapersSource
6,233,223Mechanisms of genetic control of immune responses. I. Evidence for distinct multi-step helper T-cell pathways in cellular and humoral responses to GAT.Immunogenetics1984https://conductscience.org/library/papers/6233223PubMed
6,225,732Molecular events in the processing of avidin by antigen-presenting cells (APC). I. The immune response of T lymphocytes to avidin is regulated by H-2-linked Ir genes.Immunogenetics1983https://conductscience.org/library/papers/6225732PubMed

Data dates

The date of each source this release read.

PubMed
2026-11-06
PubMed
iCite
2026-11-05
iCite
PMC's ID file
2026-11-05
PMC's ID file
NIH RePORTER's grant and paper links
2026-11-01
NIH RePORTER's grant and paper links
Trials
2026-11-12
Gene search
2026-11-11
Pipelines
2026-09-18

None in this release

  • Grants
  • Trials
  • Comments and corrections
  • Genes
  • Drugs
  • Data

Sources 11

  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • HGNCCC0
  • iCiteCC BY 4.0
  • NCBI GenePublic domain (US government)
  • NIH RePORTER's grant and paper linksPublic domain
  • Open TargetsCC0 1.0
  • PMC's ID filePublic domain (US government)
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • HGNCCC0: https://www.genenames.org/about/license/
  • iCiteCC BY 4.0
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this paper from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/papers/v1/102725

GET https://conductscience.org/api/papers/v1/102725/references?page=2

API referenceFor AI assistants