Genes
NCBI Gene
One gene with its proteins, patents, drugs, trials, grants and papers.
85,013 comparisons from ClinicalTrials.gov.
Most participants first33,758 with no events in either group come last4,361 to 4,380 of 85,013
| Comparison | With the outcome | Risk difference, 95% interval | Participants | Trial |
|---|---|---|---|---|
| PEG-IFN Alfa-2a 180μg + Ribavirin 800 mg 16 Weeks vs PEG-IFN Alfa-2a 180μg + Ribavirin 800 mg 24 Weeks: serious adverse events | 34 of 731 47 of 728 | -1.8 points -4.2 to 0.6 | 1,459 | NCT00077636 ACCELERATE Study - A Study of PEGASYS (Peginterferon Alfa-2a (40KD)) in Combination With COPEGUS (Ribavirin) in Interferon-Naive Patients With Chronic Hepatitis C (CHC) Infection. |
| Prior CD Decision App (PCDDA) vs Usual Care - No App: Number of Participants Who Underwent a Trial of Labor After Cesarean (TOLAC) Delivery | 315 of 727 338 of 732 | -2.8 points -7.9 to 2.3 | 1,459 | NCT02646423 Effect of a Patient-Centered Decision App on TOLAC |
| Prior CD Decision App (PCDDA) vs Usual Care - No App: Number of Participants Who Underwent Vaginal Birth After Cesarean (VBAC) | 231 of 727 233 of 732 | -0.1 points -4.8 to 4.7 | 1,459 | NCT02646423 Effect of a Patient-Centered Decision App on TOLAC |
| Dose-Escalated Radiation Therapy Alone vs Dose-Escalated Radiation Therapy and Short-Term Androgen-Deprivation: Number of Participants With Acute Adverse Events | 152 of 733 504 of 725 | -48.8 points -53.0 to -44.2 | 1,458 | NCT00936390 Radiation Therapy With or Without Androgen-Deprivation Therapy in Treating Patients With Prostate Cancer |
| Dose-Escalated Radiation Therapy Alone vs Dose-Escalated Radiation Therapy and Short-Term Androgen-Deprivation: serious adverse events | 20 of 733 33 of 725 | -1.8 points -3.8 to 0.1 | 1,458 | NCT00936390 Radiation Therapy With or Without Androgen-Deprivation Therapy in Treating Patients With Prostate Cancer |
| HDM SLIT-tablet (12 SQ-HDM) vs Placebo SLIT-tablet: serious adverse events | 16 of 727 6 of 731 | 1.4 points 0.1 to 2.8 | 1,458 | NCT04145219 House Dust Mite Allergy Trial In Children |
| Solanezumab vs Placebo: serious adverse events | 299 of 734 308 of 723 | -1.9 points -6.9 to 3.2 | 1,457 | NCT01127633 Continued Safety Monitoring of Solanezumab (LY2062430) in Alzheimer's Disease |
| Denosumab 60 mg Q6M vs Placebo: serious adverse events | 253 of 731 222 of 725 | 4.0 points -0.8 to 8.8 | 1,456 | NCT00089674 AMG 162 in the Treatment of Bone Loss in Subjects Undergoing Androgen-Deprivation Therapy for Non-metastatic Prostate Cancer |
| Apixaban vs Parenteral Heparin/Oral Vitamin K Antagonist (Usual Care): Number of Participants With Major Bleeding Event | 3 of 735 6 of 721 | -0.4 points -1.4 to 0.5 | 1,456 | NCT02100228 Study Of The Blood Thinner, Apixaban, For Patients Who Have An Abnormal Heart Rhythm (Atrial Fibrillation) And Expected To Have Treatment To Put Them Back Into A Normal Heart Rhythm (Cardioversion) |
| Apixaban vs Parenteral Heparin/Oral Vitamin K Antagonist (Usual Care): deaths from any cause | 1 of 735 3 of 721 | -0.3 points -1.1 to 0.4 | 1,456 | NCT02100228 Study Of The Blood Thinner, Apixaban, For Patients Who Have An Abnormal Heart Rhythm (Atrial Fibrillation) And Expected To Have Treatment To Put Them Back Into A Normal Heart Rhythm (Cardioversion) |
| Apixaban vs Parenteral Heparin/Oral Vitamin K Antagonist (Usual Care): Number of Participants With Clinically Relevant Non-Major Bleeding Events | 11 of 735 13 of 721 | -0.3 points -1.7 to 1.1 | 1,456 | NCT02100228 Study Of The Blood Thinner, Apixaban, For Patients Who Have An Abnormal Heart Rhythm (Atrial Fibrillation) And Expected To Have Treatment To Put Them Back Into A Normal Heart Rhythm (Cardioversion) |
| Apixaban vs Parenteral Heparin/Oral Vitamin K Antagonist (Usual Care): serious adverse events | 100 of 735 112 of 721 | -1.9 points -5.6 to 1.7 | 1,456 | NCT02100228 Study Of The Blood Thinner, Apixaban, For Patients Who Have An Abnormal Heart Rhythm (Atrial Fibrillation) And Expected To Have Treatment To Put Them Back Into A Normal Heart Rhythm (Cardioversion) |
| Iron Isomaltoside/Ferric Derisomaltose vs Iron Sucrose: S-Ferritin Concentration of ≥100 ng/mL and Transferrin Saturation (TSAT) of 20-50% at Any Time From Week 1 to Week 8 | 680 of 973 164 of 483 | 35.9 points 30.7 to 40.9 | 1,456 | NCT02940886 Iron Isomaltoside/Ferric Derisomaltose vs Iron Sucrose for the Treatment of Iron Deficiency Anemia (IDA) |
| Peripheral Arterial Disease vs Control: serious adverse events | 195 of 742 82 of 713 | 14.8 points 10.8 to 18.7 | 1,455 | NCT00761969 Prevention of Ischemic Events in Patients With Peripheral Arterial Disease |
| CAS Group vs CEA Group: serious adverse events | 376 of 1,089 118 of 364 | 2.1 points -3.6 to 7.5 | 1,453 | NCT00106938 Carotid Angioplasty and Stenting Versus Endarterectomy in Asymptomatic Subjects Who Are at Standard Risk for Carotid Endarterectomy With Significant Extracranial Carotid Stenotic Disease (ACT I) |
| MEDI8897 50 mg vs Placebo: Number of Participants Hopitalized Due to Respiratory Syncytial Virus (RSV) Confirmed Lower Respiartory Tract Infection (LRTI) | 8 of 969 20 of 484 | -3.3 points -5.5 to -1.7 | 1,453 | NCT02878330 A Study to Evaluate the Safety and Efficacy of MEDI8897 for the Prevention of Medically Attended RSV LRTI in Healthy Preterm Infants. |
| MEDI8897 50 mg vs Placebo: Number of Participants With Medically Attended Respiratory Syncytial Virus (RSV) Confirmed Lower Respiratory Tract Infection (LRTI) | 25 of 969 46 of 484 | -6.9 points -10.0 to -4.3 | 1,453 | NCT02878330 A Study to Evaluate the Safety and Efficacy of MEDI8897 for the Prevention of Medically Attended RSV LRTI in Healthy Preterm Infants. |
| Intervention vs Control: Surgical Failure | 20 of 968 12 of 484 | -0.4 points -2.4 to 1.1 | 1,452 | NCT00347776 Study of Azithromycin to Prevent Recurrent Trichiasis Following Surgery in Ethiopia |
| Intervention vs Control: Recurrent Trichiasis in Tetracycline and Azithromycin Groups | 62 of 968 45 of 484 | -2.9 points -6.1 to -0.0 | 1,452 | NCT00347776 Study of Azithromycin to Prevent Recurrent Trichiasis Following Surgery in Ethiopia |
| Intervention vs Control: deaths from any cause | 0 of 968 2 of 484 | -0.4 points -1.5 to 0.1 | 1,452 | NCT00347776 Study of Azithromycin to Prevent Recurrent Trichiasis Following Surgery in Ethiopia |
Code
curl "https://conductscience.org/api/comparisons/v1?page=219"
Response
The first 2 of this page's 20 results. GET /api/comparisons/v1?page=219
{
"data": {
"total": 85013,
"results": [
{
"id": "NCT00077636-sae",
"title": "PEG-IFN Alfa-2a 180μg + Ribavirin 800 mg 16 Weeks vs PEG-IFN Alfa-2a 180μg + Ribavirin 800 mg 24 Weeks: serious adverse events",
"summary": "34 of 731 against 47 of 728; risk difference -1.8 points, 95% interval -4.2 to 0.6; NCT00077636, ACCELERATE Study - A Study of PEGASYS (Peginterferon Alfa-2a (40KD)) in Combination With COPEGUS (Ribavirin) in Interferon-Naive Patients With Chronic Hepatitis C (CHC) Infection.",
"record": "/library/comparisons/NCT00077636-sae",
"nct_id": "NCT00077636",
"kind": "serious-adverse-events",
"participants": 1459,
"risk_difference": {
"value": -0.018048811653462823,
"lower": -0.04212204793002142,
"upper": 0.005647801556671741
},
"group_1": "34 of 731",
"group_2": "47 of 728",
"difference": "-1.8 points",
"interval": "-4.2 to 0.6",
"trial_title": "ACCELERATE Study - A Study of PEGASYS (Peginterferon Alfa-2a (40KD)) in Combination With COPEGUS (Ribavirin) in Interferon-Naive Patients With Chronic Hepatitis C (CHC) Infection."
},
{
"id": "NCT02646423-b8156f04",
"title": "Prior CD Decision App (PCDDA) vs Usual Care - No App: Number of Participants Who Underwent a Trial of Labor After Cesarean (TOLAC) Delivery",
"summary": "315 of 727 against 338 of 732; risk difference -2.8 points, 95% interval -7.9 to 2.3; NCT02646423, Effect of a Patient-Centered Decision App on TOLAC",
"record": "/library/comparisons/NCT02646423-b8156f04",
"nct_id": "NCT02646423",
"kind": "outcome",
"participants": 1459,
"risk_difference": {
"value": -0.028461151073729152,
"lower": -0.0792318307802696,
"upper": 0.022522003896597087
},
"group_1": "315 of 727",
"group_2": "338 of 732",
"difference": "-2.8 points",
"interval": "-7.9 to 2.3",
"trial_title": "Effect of a Patient-Centered Decision App on TOLAC"
}
],
"no_events": 33758,
"columns": [
{
"key": "title",
"label": "Comparison"
},
{
"key": "group_1",
"label": "With the outcome",
"under": "group_2"
},
{
"key": "difference",
"label": "Risk difference, 95% interval",
"under": "interval"
},
{
"key": "participants",
"label": "Participants"
},
{
"key": "nct_id",
"label": "Trial",
"under": "trial_title"
}
],
"order": "Most participants first",
"kinds": {
"all": 85013,
"outcome": 33568,
"serious-adverse-events": 31897,
"deaths": 19548
}
},
"release": "trial-comparisons-2026-03-23-0.1.0",
"terms": [
{
"source": "ClinicalTrials.gov's posted results, through CTTI's AACT",
"license": "ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299",
"notice": "ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.",
"short": "Freely available. Acknowledgement requested"
},
{
"source": "ClinicalTrials.gov",
"license": "none stated",
"notice": "ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.",
"short": "No license stated"
}
],
"next": "/api/comparisons/v1?page=220",
"request_id": "T7be9xnJTx8gniHD"
}Ask about these results. The first 10 go in the prompt.
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.
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For software
Every answer on this page is also JSON, under /api/comparisons/v1. No key.
GET https://conductscience.org/api/comparisons/v1?q=placebo%20heart%20failure&kind=outcome
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