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85,013 comparisons from ClinicalTrials.gov.

85,013 comparisons

Most participants first33,758 with no events in either group come last4,361 to 4,380 of 85,013

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ComparisonWith the outcomeRisk difference, 95% intervalParticipantsTrial
PEG-IFN Alfa-2a 180μg + Ribavirin 800 mg 16 Weeks vs PEG-IFN Alfa-2a 180μg + Ribavirin 800 mg 24 Weeks: serious adverse events34 of 731

47 of 728

-1.8 points

-4.2 to 0.6

1,459NCT00077636

ACCELERATE Study - A Study of PEGASYS (Peginterferon Alfa-2a (40KD)) in Combination With COPEGUS (Ribavirin) in Interferon-Naive Patients With Chronic Hepatitis C (CHC) Infection.

Prior CD Decision App (PCDDA) vs Usual Care - No App: Number of Participants Who Underwent a Trial of Labor After Cesarean (TOLAC) Delivery315 of 727

338 of 732

-2.8 points

-7.9 to 2.3

1,459NCT02646423

Effect of a Patient-Centered Decision App on TOLAC

Prior CD Decision App (PCDDA) vs Usual Care - No App: Number of Participants Who Underwent Vaginal Birth After Cesarean (VBAC)231 of 727

233 of 732

-0.1 points

-4.8 to 4.7

1,459NCT02646423

Effect of a Patient-Centered Decision App on TOLAC

Dose-Escalated Radiation Therapy Alone vs Dose-Escalated Radiation Therapy and Short-Term Androgen-Deprivation: Number of Participants With Acute Adverse Events152 of 733

504 of 725

-48.8 points

-53.0 to -44.2

1,458NCT00936390

Radiation Therapy With or Without Androgen-Deprivation Therapy in Treating Patients With Prostate Cancer

Dose-Escalated Radiation Therapy Alone vs Dose-Escalated Radiation Therapy and Short-Term Androgen-Deprivation: serious adverse events20 of 733

33 of 725

-1.8 points

-3.8 to 0.1

1,458NCT00936390

Radiation Therapy With or Without Androgen-Deprivation Therapy in Treating Patients With Prostate Cancer

HDM SLIT-tablet (12 SQ-HDM) vs Placebo SLIT-tablet: serious adverse events16 of 727

6 of 731

1.4 points

0.1 to 2.8

1,458NCT04145219

House Dust Mite Allergy Trial In Children

Solanezumab vs Placebo: serious adverse events299 of 734

308 of 723

-1.9 points

-6.9 to 3.2

1,457NCT01127633

Continued Safety Monitoring of Solanezumab (LY2062430) in Alzheimer's Disease

Denosumab 60 mg Q6M vs Placebo: serious adverse events253 of 731

222 of 725

4.0 points

-0.8 to 8.8

1,456NCT00089674

AMG 162 in the Treatment of Bone Loss in Subjects Undergoing Androgen-Deprivation Therapy for Non-metastatic Prostate Cancer

Apixaban vs Parenteral Heparin/Oral Vitamin K Antagonist (Usual Care): Number of Participants With Major Bleeding Event3 of 735

6 of 721

-0.4 points

-1.4 to 0.5

1,456NCT02100228

Study Of The Blood Thinner, Apixaban, For Patients Who Have An Abnormal Heart Rhythm (Atrial Fibrillation) And Expected To Have Treatment To Put Them Back Into A Normal Heart Rhythm (Cardioversion)

Apixaban vs Parenteral Heparin/Oral Vitamin K Antagonist (Usual Care): deaths from any cause1 of 735

3 of 721

-0.3 points

-1.1 to 0.4

1,456NCT02100228

Study Of The Blood Thinner, Apixaban, For Patients Who Have An Abnormal Heart Rhythm (Atrial Fibrillation) And Expected To Have Treatment To Put Them Back Into A Normal Heart Rhythm (Cardioversion)

Apixaban vs Parenteral Heparin/Oral Vitamin K Antagonist (Usual Care): Number of Participants With Clinically Relevant Non-Major Bleeding Events11 of 735

13 of 721

-0.3 points

-1.7 to 1.1

1,456NCT02100228

Study Of The Blood Thinner, Apixaban, For Patients Who Have An Abnormal Heart Rhythm (Atrial Fibrillation) And Expected To Have Treatment To Put Them Back Into A Normal Heart Rhythm (Cardioversion)

Apixaban vs Parenteral Heparin/Oral Vitamin K Antagonist (Usual Care): serious adverse events100 of 735

112 of 721

-1.9 points

-5.6 to 1.7

1,456NCT02100228

Study Of The Blood Thinner, Apixaban, For Patients Who Have An Abnormal Heart Rhythm (Atrial Fibrillation) And Expected To Have Treatment To Put Them Back Into A Normal Heart Rhythm (Cardioversion)

Iron Isomaltoside/Ferric Derisomaltose vs Iron Sucrose: S-Ferritin Concentration of ≥100 ng/mL and Transferrin Saturation (TSAT) of 20-50% at Any Time From Week 1 to Week 8680 of 973

164 of 483

35.9 points

30.7 to 40.9

1,456NCT02940886

Iron Isomaltoside/Ferric Derisomaltose vs Iron Sucrose for the Treatment of Iron Deficiency Anemia (IDA)

Peripheral Arterial Disease vs Control: serious adverse events195 of 742

82 of 713

14.8 points

10.8 to 18.7

1,455NCT00761969

Prevention of Ischemic Events in Patients With Peripheral Arterial Disease

CAS Group vs CEA Group: serious adverse events376 of 1,089

118 of 364

2.1 points

-3.6 to 7.5

1,453NCT00106938

Carotid Angioplasty and Stenting Versus Endarterectomy in Asymptomatic Subjects Who Are at Standard Risk for Carotid Endarterectomy With Significant Extracranial Carotid Stenotic Disease (ACT I)

MEDI8897 50 mg vs Placebo: Number of Participants Hopitalized Due to Respiratory Syncytial Virus (RSV) Confirmed Lower Respiartory Tract Infection (LRTI)8 of 969

20 of 484

-3.3 points

-5.5 to -1.7

1,453NCT02878330

A Study to Evaluate the Safety and Efficacy of MEDI8897 for the Prevention of Medically Attended RSV LRTI in Healthy Preterm Infants.

MEDI8897 50 mg vs Placebo: Number of Participants With Medically Attended Respiratory Syncytial Virus (RSV) Confirmed Lower Respiratory Tract Infection (LRTI)25 of 969

46 of 484

-6.9 points

-10.0 to -4.3

1,453NCT02878330

A Study to Evaluate the Safety and Efficacy of MEDI8897 for the Prevention of Medically Attended RSV LRTI in Healthy Preterm Infants.

Intervention vs Control: Surgical Failure20 of 968

12 of 484

-0.4 points

-2.4 to 1.1

1,452NCT00347776

Study of Azithromycin to Prevent Recurrent Trichiasis Following Surgery in Ethiopia

Intervention vs Control: Recurrent Trichiasis in Tetracycline and Azithromycin Groups62 of 968

45 of 484

-2.9 points

-6.1 to -0.0

1,452NCT00347776

Study of Azithromycin to Prevent Recurrent Trichiasis Following Surgery in Ethiopia

Intervention vs Control: deaths from any cause0 of 968

2 of 484

-0.4 points

-1.5 to 0.1

1,452NCT00347776

Study of Azithromycin to Prevent Recurrent Trichiasis Following Surgery in Ethiopia

Request

GET /api/comparisons/v1

Words from a trial's title, conditions or interventions, its outcome or its groups, or an NCT number.

An outcome counted in participants, the serious adverse events, or the deaths from any cause.

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Code

Show the call in
curl "https://conductscience.org/api/comparisons/v1?page=219"

Response

The first 2 of this page's 20 results. GET /api/comparisons/v1?page=219

{
  "data": {
    "total": 85013,
    "results": [
      {
        "id": "NCT00077636-sae",
        "title": "PEG-IFN Alfa-2a 180μg + Ribavirin 800 mg 16 Weeks vs PEG-IFN Alfa-2a 180μg + Ribavirin 800 mg 24 Weeks: serious adverse events",
        "summary": "34 of 731 against 47 of 728; risk difference -1.8 points, 95% interval -4.2 to 0.6; NCT00077636, ACCELERATE Study - A Study of PEGASYS (Peginterferon Alfa-2a (40KD)) in Combination With COPEGUS (Ribavirin) in Interferon-Naive Patients With Chronic Hepatitis C (CHC) Infection.",
        "record": "/library/comparisons/NCT00077636-sae",
        "nct_id": "NCT00077636",
        "kind": "serious-adverse-events",
        "participants": 1459,
        "risk_difference": {
          "value": -0.018048811653462823,
          "lower": -0.04212204793002142,
          "upper": 0.005647801556671741
        },
        "group_1": "34 of 731",
        "group_2": "47 of 728",
        "difference": "-1.8 points",
        "interval": "-4.2 to 0.6",
        "trial_title": "ACCELERATE Study - A Study of PEGASYS (Peginterferon Alfa-2a (40KD)) in Combination With COPEGUS (Ribavirin) in Interferon-Naive Patients With Chronic Hepatitis C (CHC) Infection."
      },
      {
        "id": "NCT02646423-b8156f04",
        "title": "Prior CD Decision App (PCDDA) vs Usual Care - No App: Number of Participants Who Underwent a Trial of Labor After Cesarean (TOLAC) Delivery",
        "summary": "315 of 727 against 338 of 732; risk difference -2.8 points, 95% interval -7.9 to 2.3; NCT02646423, Effect of a Patient-Centered Decision App on TOLAC",
        "record": "/library/comparisons/NCT02646423-b8156f04",
        "nct_id": "NCT02646423",
        "kind": "outcome",
        "participants": 1459,
        "risk_difference": {
          "value": -0.028461151073729152,
          "lower": -0.0792318307802696,
          "upper": 0.022522003896597087
        },
        "group_1": "315 of 727",
        "group_2": "338 of 732",
        "difference": "-2.8 points",
        "interval": "-7.9 to 2.3",
        "trial_title": "Effect of a Patient-Centered Decision App on TOLAC"
      }
    ],
    "no_events": 33758,
    "columns": [
      {
        "key": "title",
        "label": "Comparison"
      },
      {
        "key": "group_1",
        "label": "With the outcome",
        "under": "group_2"
      },
      {
        "key": "difference",
        "label": "Risk difference, 95% interval",
        "under": "interval"
      },
      {
        "key": "participants",
        "label": "Participants"
      },
      {
        "key": "nct_id",
        "label": "Trial",
        "under": "trial_title"
      }
    ],
    "order": "Most participants first",
    "kinds": {
      "all": 85013,
      "outcome": 33568,
      "serious-adverse-events": 31897,
      "deaths": 19548
    }
  },
  "release": "trial-comparisons-2026-03-23-0.1.0",
  "terms": [
    {
      "source": "ClinicalTrials.gov's posted results, through CTTI's AACT",
      "license": "ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299",
      "notice": "ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.",
      "short": "Freely available. Acknowledgement requested"
    },
    {
      "source": "ClinicalTrials.gov",
      "license": "none stated",
      "notice": "ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.",
      "short": "No license stated"
    }
  ],
  "next": "/api/comparisons/v1?page=220",
  "request_id": "T7be9xnJTx8gniHD"
}

Ask about these results. The first 10 go in the prompt.

About this data
Holds
85,013 comparisons
From ClinicalTrials.gov. Counted 10 Nov 2026.
Release
23 Mar 2026
trial-comparisons-2026-03-23-0.1.0
Checked
20 of 20 review comparisons traced to ClinicalTrials.gov, and all 510,078 numbers calculated again apart from the builder agree
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Sources 2

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.

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