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Disease · MONDO_0000262

otomycosis

6 sourcesdiseases-2026-09-18-0.1.0

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ConductScience Library. otomycosis. Diseases, record MONDO_0000262. Release diseases-2026-09-18-0.1.0, 18 Sept 2026. https://conductscience.org/library/diseases/MONDO_0000262

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Disease

Names and IDs as Open Targets gives them. Its IDs in MeSH, Orphanet, the Disease Ontology and the NCI Thesaurus are those Open Targets states for it.

Name
otomycosis
Open Targets
Open Targets ID
MONDO_0000262
Open Targets
Other names
external ear fungal infectious disease
Open Targets
Disease Ontology
DOID:0050147
Disease Ontology
MeSH
D059249
MeSH
Highest stage of its drugs
Phase 3, for 2 of its 7 drugs, from ClinicalTrials.gov
Open Targets

Drugs7

The drugs Open Targets' clinical reports study for the disease, the highest stage first, then the most trial reports. The stage is Open Targets', the highest any of its sources reports for the pair, and each row names the sources that report it.

DrugChEMBL IDTypeOpen Targets' stageStage reported byReportsOf them trialsTrials shown hereSource
CLOTRIMAZOLECHEMBL104Small moleculePhase 3ClinicalTrials.gov555Drugs and targets
MICONAZOLECHEMBL91Small moleculePhase 3ClinicalTrials.gov333Drugs and targets
POVIDONE-IODINECHEMBL1201724Phase 1ClinicalTrials.gov222Drugs and targets
NYSTATINCHEMBL5465559Early phase 1ClinicalTrials.gov111Drugs and targets
BORIC ACIDCHEMBL42403Small moleculeUnknownClinicalTrials.gov333Drugs and targets
SALICYLIC ACIDCHEMBL424Small moleculeUnknownClinicalTrials.gov111Drugs and targets
TERBINAFINE HYDROCHLORIDECHEMBL1200832Small moleculeUnknownClinicalTrials.gov111Drugs and targets

Targets0

The targets ChEMBL's mechanism records give for the disease's drugs, through Open Targets, the most drugs first. A mechanism record says what a drug acts on, not that the target causes the disease.

None in this release.

Trials11

Trials an Open Targets clinical report links to the disease, posted results first, then the largest. A trial is shown when the release's checks confirm its link to the disease and Drugs and targets shows its link to one of the disease's drugs.

TrialTitlePhaseParticipantsResults first postedConditionsDrugsLinked bySource
NCT04432376Efficacy and Safety Study of Miconazole Oil Versus Vehicle on Fungal Infection of the Ear Canal (Otomycosis)Phase 2/33822022-11-04OtomycosisMICONAZOLEIts record names the diseaseClinicalTrials.gov
NCT01993823Clinical Study to Assess the Efficacy and Safety of G238 Compared to Clotrimazole Otic Solution in the Treatment of OtomycosisPhase 31902017-02-13OtomycosisCLOTRIMAZOLEIts record names the diseaseClinicalTrials.gov
NCT03130738Dose-Ranging Study for Miconazole Oil for Treatment of OtomycosisPhase 2652020-05-08OtomycosisMICONAZOLEIts record names the diseaseClinicalTrials.gov
NCT01547221Effectiveness of 3% Boric Acid in 70% Alcohol Versus 1% Clotrimazole Solution in Otomycosis PatientsNot applicable120OtomycosisBORIC ACID, CLOTRIMAZOLEIts record names the diseaseClinicalTrials.gov
NCT05660382Phase III Efficacy and Safety Study of Miconazole Oil for OtomycosisPhase 3112OtomycosisMICONAZOLEIts record names the diseaseClinicalTrials.gov
NCT04824261Effectiveness of 4% Boric Acid in Distilled Water Versus Clotrimazole Solution in Otomycosis Patients.Not applicable100OtomycosisBORIC ACID, CLOTRIMAZOLEIts record names the diseaseClinicalTrials.gov
NCT06339294Efficacy of Pyodine Soaked Gelfoam vs Single Topical Application of Clotrimazole in Otomycosis TreatmentPhase 190OtomycosisCLOTRIMAZOLE, POVIDONE-IODINEIts record names the diseaseClinicalTrials.gov
NCT07295210Boric Acid Versus 10% Povidone Iodine Solution in Treatment of OtomycosisNot applicable60OtomycosisBORIC ACID, POVIDONE-IODINEIts record names the diseaseClinicalTrials.gov
NCT07535424Comparative Efficacy of Topical Clotrimazole Versus 2% Salicylic Acid in OtomycosisNot applicable60OtomycosisCLOTRIMAZOLE, SALICYLIC ACIDIts record names the diseaseClinicalTrials.gov
NCT07152327Terbinafine Hydrochloride for the Treatment of OtomycosisNot applicable50Otomycosis, Fungal Ear InfectionTERBINAFINE HYDROCHLORIDEIts record names the diseaseClinicalTrials.gov

1 to 10 of 11

See all 11 trials

Comparisons in its trials1

Comparisons Trial comparisons calculated in the trials shown here, most participants first. A comparison in one of these trials does not always compare a treatment for the disease, so read the two groups.

ComparisonGroup 1, with the outcomeGroup 2, with the outcomeParticipantsTrial
G238 vs Clotrimazole: serious adverse events0 of 890 of 85174NCT01993823

Papers from its trials7

The papers the trials shown here list on ClinicalTrials.gov as their results (RESULT) or as drawn from them (DERIVED), results first, newest first.

PMIDListed asTrials listing itSource
36532230RESULT1PubMed
29786478RESULT1PubMed
28549873RESULT1PubMed
23984100RESULT1PubMed
12572722RESULT1PubMed
5526992RESULT1PubMed
34033120DERIVED1PubMed

Data dates

The date of each source this release read.

Open Targets
2026-09-18
Open Targets
Drug links and their checks, from Drugs and targets
2026-09-18
Drugs and targets
ClinicalTrials.gov, from Trials
2026-11-12
Trials
Comparisons, from Trial comparisons
2026-03-23
Trial comparisons
PubMed, for the checks
2026-11-06
PubMed
MeSH, for the checks
2026-11-10
MeSH

Sources 6

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • NLM's MeSHNLM's terms
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • NLM's MeSHNLM's
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this disease from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/diseases/v1/MONDO_0000262

GET https://conductscience.org/api/diseases/v1/MONDO_0000262/drugs