Disease · MONDO_0005156
encephalomyelitis
6 sourcesdiseases-2026-09-18-0.1.0
Cite this record
ConductScience Library. encephalomyelitis. Diseases, record MONDO_0005156. Release diseases-2026-09-18-0.1.0, 18 Sept 2026. https://conductscience.org/library/diseases/MONDO_0005156
On this page
Disease
Names and IDs as Open Targets gives them. Its IDs in MeSH, Orphanet, the Disease Ontology and the NCI Thesaurus are those Open Targets states for it.
- Other names
ENCEPH INFLAMM, Encephalitis &/or myelitis, Encephalitis/myelitis NOS, Encephalitis/myelitis NOS (disorder), Encephalomyelitis (disorder), Encephalomyelitis NOS, Encephalomyelitis NOS (disorder), Encephalomyelitis, Inflammatory, INFLAMM ENCEPH, Inflammatory Encephalomyelitis, MYELOENCEPH, Myeloencephalitides, Myeloencephalitis, central nervous system inflammation, encephalitis, encephalitis and/or myelitis, inflammation of central nervous system
- Open Targets
Drugs5
The drugs Open Targets' clinical reports study for the disease, the highest stage first, then the most trial reports. The stage is Open Targets', the highest any of its sources reports for the pair, and each row names the sources that report it.
| Drug | ChEMBL ID | Type | Open Targets' stage | Stage reported by | Reports | Of them trials | Trials shown here | Source |
|---|---|---|---|---|---|---|---|---|
| RINTATOLIMOD | CHEMBL2107862 | Phase 3 | ClinicalTrials.gov | 1 | 1 | 1 | Drugs and targets | |
| HUMAN IMMUNOGLOBULIN G | CHEMBL1201599 | Phase 2/3 | ClinicalTrials.gov | 1 | 1 | 0 | Drugs and targets | |
| TACROLIMUS ANHYDROUS | CHEMBL269732 | Small molecule | Phase 2/3 | ClinicalTrials.gov | 1 | 1 | 1 | Drugs and targets |
| RITUXIMAB | CHEMBL1201576 | Antibody | Phase 1 | ClinicalTrials.gov | 1 | 1 | 1 | Drugs and targets |
| TACROLIMUS | CHEMBL3989887 | Small molecule | Unknown | ClinicalTrials.gov | 1 | 1 | 1 | Drugs and targets |
Targets3
The targets ChEMBL's mechanism records give for the disease's drugs, through Open Targets, the most drugs first. A mechanism record says what a drug acts on, not that the target causes the disease.
| Target | Protein | Its drugs that act on it | Mechanisms | Highest stage of those drugs | Gene in Genes | Source |
|---|---|---|---|---|---|---|
| FKBP1A | Peptidyl-prolyl cis-trans isomerase FKBP1A | 2 | FK506-binding protein 1A inhibitor | Phase 2/3 | https://conductscience.org/library/genes/2280 | Drugs and targets |
| MS4A1 | B-lymphocyte antigen CD20 | 1 | B-lymphocyte antigen CD20 binding agent | Phase 1 | https://conductscience.org/library/genes/931 | Drugs and targets |
| TLR3 | Toll-like receptor 3 | 1 | Toll-like receptor 3 agonist | Phase 3 | https://conductscience.org/library/genes/7098 | Drugs and targets |
Trials4
Trials an Open Targets clinical report links to the disease, posted results first, then the largest. A trial is shown when the release's checks confirm its link to the disease and Drugs and targets shows its link to one of the disease's drugs.
| Trial | Title | Phase | Participants | Results first posted | Conditions | Drugs | Linked by | Source |
|---|---|---|---|---|---|---|---|---|
| NCT00378326 | Immunotherapy of the Paraneoplastic Syndromes | Not applicable | 26 | 2016-02-23 | Paraneoplastic Syndromes | TACROLIMUS | Its record names the disease | ClinicalTrials.gov |
| NCT00215800 | The Study of the Safety and Efficacy of Ampligen in Chronic Fatigue Syndrome | Phase 3 | 234 | Chronic Fatigue Syndrome, Myalgic Encephalomyelitis | RINTATOLIMOD | Open Targets' reading, confirmed by NLM's indexing of its papers | ClinicalTrials.gov | |
| NCT00545493 | Efficacy of Tacrolimus and I.V.-Immunoglobulins in Rasmussen Encephalitis | Phase 2/3 | 16 | Rasmussen Encephalitis | TACROLIMUS ANHYDROUS | Open Targets' reading of its record | ClinicalTrials.gov | |
| NCT00259805 | A Pilot Study of the Use of Rituximab in the Treatment of Chronic Focal Encephalitis | Phase 1 | 10 | Chronic Focal Encephalitis, Rasmussen's Encephalitis | RITUXIMAB | Open Targets' reading of its record | ClinicalTrials.gov |
Comparisons in its trials0
Comparisons Trial comparisons calculated in the trials shown here, most participants first. A comparison in one of these trials does not always compare a treatment for the disease, so read the two groups.
None in this release.
Papers from its trials3
The papers the trials shown here list on ClinicalTrials.gov as their results (RESULT) or as drawn from them (DERIVED), results first, newest first.
Data dates
The date of each source this release read.
Sources 6
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- NLM's MeSHNLM's terms
- Open TargetsCC0 1.0
- PubMedNLM's terms
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- NLM's MeSHNLM's
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this disease from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/diseases/v1/MONDO_0005156
GET https://conductscience.org/api/diseases/v1/MONDO_0005156/drugs