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Disease · MONDO_0005233

Comparisons in its trials902

Comparisons Trial comparisons calculated in the trials shown here, most participants first. A comparison in one of these trials does not always compare a treatment for the disease, so read the two groups.

ComparisonGroup 1, with the outcomeGroup 2, with the outcomeParticipantsTrialSource
Biomarker Cohort vs Non-biomarker Cohort: deaths from any cause364 of 6183,780 of 4,6615,279NCT05834348Trial comparisons
Darbepoetin Alfa vs Placebo: deaths from any cause1,273 of 1,685657 of 8332,518NCT00858364Trial comparisons
Darbepoetin Alfa vs Placebo: serious adverse events524 of 1,685259 of 8332,518NCT00858364Trial comparisons
Darbepoetin Alfa vs Placebo: Number of Participants Who Developed Neutralizing Antibodies to Darbepoetin Alfa0 of 1,6060 of 8032,409NCT00858364Trial comparisons
GSK1572932 Group vs Placebo Group: Number of Patients With Serious Adverse Events (SAEs) - Up to Data Lock Point (DLP)330 of 1,515164 of 7572,272NCT00480025Trial comparisons
GSK1572932 Group vs Placebo Group: deaths from any cause30 of 1,51517 of 7572,272NCT00480025Trial comparisons
GSK1572932 Group vs Placebo Group: serious adverse events330 of 1,515164 of 7572,272NCT00480025Trial comparisons
Tecemotide (L-BLP25) + Cyclophosphamide vs Saline + Placebo: serious adverse events303 of 1,024151 of 4771,501NCT00409188Trial comparisons
Arm I (Chemotherapy) vs Arm II (Chemotherapy, Bevacizumab): serious adverse events424 of 738563 of 7351,473NCT00324805Trial comparisons
Vandetanib 100 mg Plus Docetaxel vs Placebo Plus Docetaxel: Objective Response Rate (ORR)120 of 69471 of 6971,391NCT00312377Trial comparisons
Vandetanib 100 mg Plus Docetaxel vs Placebo Plus Docetaxel: Disease Control Rate (DCR)413 of 694380 of 6971,391NCT00312377Trial comparisons
Vandetanib 100 mg Plus Docetaxel vs Placebo Plus Docetaxel: serious adverse events263 of 694232 of 6971,391NCT00312377Trial comparisons
Arm I (Chemo +/- Bevacizumab) vs Arm II (Chemo, Cetuximab, +/- Bevacizumab): deaths from any cause593 of 657570 of 6561,313NCT00946712Trial comparisons
Nintedanib Plus Docetaxel vs Placebo Plus Docetaxel: deaths from any cause107 of 65277 of 6551,307NCT00805194Trial comparisons
Nintedanib Plus Docetaxel vs Placebo Plus Docetaxel: serious adverse events224 of 652206 of 6551,307NCT00805194Trial comparisons
Arm I (Chemo +/- Bevacizumab) vs Arm II (Chemo, Cetuximab, +/- Bevacizumab): serious adverse events66 of 63297 of 6271,259NCT00946712Trial comparisons
Pembrolizumab vs Chemotherapy (SOC Treatment): Number of Participants Who Discontinued Study Treatment Due to an Adverse Event (AE)126 of 63693 of 6151,251NCT02220894Trial comparisons
Pembrolizumab vs Chemotherapy (SOC Treatment): Number of Participants Who Experienced At Least One Adverse Event (AE)608 of 636606 of 6151,251NCT02220894Trial comparisons
Ramucirumab and Docetaxel vs Placebo and Docetaxel: serious adverse events284 of 627281 of 6181,245NCT01168973Trial comparisons
Vandetanib vs Erlotinib: Objective Response Rate (ORR)75 of 62374 of 6171,240NCT00364351Trial comparisons

diseases-2026-09-18-0.1.0

Sources 6

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • NLM's MeSHNLM's terms
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • NLM's MeSHNLM's
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

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