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Drug · CHEMBL113

Comparisons in its trials35

Comparisons Trial comparisons calculated in the trials whose record names the drug, most participants first. A comparison in one of its trials does not always compare the drug, so read the two groups.

ComparisonGroup 1, with the outcomeGroup 2, with the outcomeParticipantsTrialSource
Caffeine vs Placebo: serious adverse events0 of 1030 of 102205NCT02461693Trial comparisons
Paracetamol/Caffeine Tablet vs Paracetamol Powder: serious adverse events0 of 710 of 71142NCT01466348Trial comparisons
CPC Adminstration vs Placebo Administration: deaths from any cause0 of 660 of 63129NCT04972123Trial comparisons
CPC Adminstration vs Placebo Administration: serious adverse events0 of 660 of 63129NCT04972123Trial comparisons
Caffeine vs Placebo: Occurence of Post Extubatory Respiratory Adverse Events.17 of 3634 of 3672NCT00273754Trial comparisons
Caffeine vs Placebo: Number of Children Who Developed Postextubation Adverse Respiratory Events Compared to Placebo.11 of 3621 of 3672NCT00273754Trial comparisons
Caffeine vs Placebo: serious adverse events0 of 360 of 3672NCT00273754Trial comparisons
Reference Product vs Test Product: serious adverse events0 of 360 of 3672NCT02629354Trial comparisons
Experimental vs Control: deaths from any cause0 of 330 of 3164NCT03577730Trial comparisons
Experimental vs Control: serious adverse events2 of 334 of 3164NCT03577730Trial comparisons
Experimental vs Control: Percentage of Delirious Patients Per Group7 of 3014 of 3060NCT03577730Trial comparisons
CPC Administration vs Placebo Administration: Percentage of Patients Who Have Asystolic Pauses > 3 Seconds in the CPC and Placebo Arms2 of 321 of 2759NCT04972123Trial comparisons
Experimental vs Control: Number of Participants With Anxiety as Assessed by the Hospitalized Anxiety and Depression Scale (HADS-A)2 of 282 of 2755NCT03577730Trial comparisons
Experimental vs Control: Number of Participants With Depression as Assessed by the Hospitalized Anxiety and Depression Scale (HADS-D)2 of 281 of 2755NCT03577730Trial comparisons
Caffeine Arm vs Placebo Arm: deaths from any cause0 of 240 of 2751NCT04950660Trial comparisons
Caffeine Arm vs Placebo Arm: serious adverse events0 of 240 of 2751NCT04950660Trial comparisons
Caffeine vs Placebo: serious adverse events0 of 180 of 2038NCT00879775Trial comparisons
D-amphetamine vs Caffeine Pills: serious adverse events0 of 120 of 1224NCT00363298Trial comparisons
Early Caffeine vs Routine Caffeine: Intubation3 of 117 of 1021NCT01783561Trial comparisons
Early Caffeine vs Routine Caffeine: Subjects Requiring Inotropes in the First 24 Hours0 of 112 of 1021NCT01783561Trial comparisons

pipelines-2026-09-18-0.3.1

Sources 7

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ConductCognition's list of its testsOur own data
  • ClinicalTrials.govNo license stated
  • NLM's MeSHNLM's terms
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ConductCognition's list of its testsOur own data: ConductCognition's list of its tests, https://conductcognition.com
  • ClinicalTrials.govnone stated
  • NLM's MeSHNLM's
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this list from software.

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