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Drug · CHEMBL601

AMINOLEVULINIC ACID

7 sourcespipelines-2026-09-18-0.3.1

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ConductScience Library. AMINOLEVULINIC ACID. Drugs and targets, record CHEMBL601. Release pipelines-2026-09-18-0.3.1, 18 Sept 2026. https://conductscience.org/library/drugs/CHEMBL601

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Drug

Names and IDs as ChEMBL gives them, through Open Targets.

Name
AMINOLEVULINIC ACID
ChEMBL
ChEMBL ID
CHEMBL601
ChEMBL
Type
Small molecule
ChEMBL
Other names
.delta.-aminolevulinic acid
ChEMBL
Other form
AMINOLEVULINIC ACID HYDROCHLORIDE, CHEMBL1200582
Drugs and targets
DrugBank
DB00855
DrugBank
InChIKey
ZGXJTSGNIOSYLO-UHFFFAOYSA-N
ChEMBL
Open Targets' highest stage
Approval, for 3 of its 30 diseases, from ATC and TTD
Open Targets

Targets0

The targets ChEMBL's mechanism records give for the drug, through Open Targets. A mechanism record says what the drug acts on, not how strongly.

None in this release.

Diseases30

The diseases Open Targets' clinical reports study the drug for, the most trial reports first. The stage is Open Targets', the highest any of its sources reports for the pair, and each row names the sources that report it.

DiseaseOpen Targets' stageStage reported byReportsOf them trialsIts drugs
actinic keratosisApprovalTTD2019https://conductscience.org/library/drugs?q=MONDO_0005173
glioblastomaPhase 3ClinicalTrials.gov1111https://conductscience.org/library/drugs?q=MONDO_0018177
basal cell carcinomaPhase 3ClinicalTrials.gov1010https://conductscience.org/library/drugs?q=MONDO_0020804
acneApprovalTTD98https://conductscience.org/library/drugs?q=MONDO_0011438
malignant gliomaPhase 2ClinicalTrials.gov33https://conductscience.org/library/drugs?q=MONDO_0100342
lip and oral cavity carcinomaPhase 2ClinicalTrials.gov22https://conductscience.org/library/drugs?q=MONDO_0023644
neurofibromaPhase 2ClinicalTrials.gov22https://conductscience.org/library/drugs?q=MONDO_0016755
neurofibromatosis type 1Phase 2ClinicalTrials.gov22https://conductscience.org/library/drugs?q=MONDO_0018975
non-melanoma skin carcinomaPhase 2ClinicalTrials.gov22https://conductscience.org/library/drugs?q=EFO_0009260
oral cavity neoplasmPhase 2ClinicalTrials.gov22https://conductscience.org/library/drugs?q=MONDO_0021245

Trials71

Trials whose record names the drug by a name ChEMBL states, posted results first, then the largest. Open Targets read each trial's text to find its drugs. 12 more rest on that reading alone and are shown because the trials' posted result groups or NLM's indexing of their papers name the drug. 51 more that Open Targets linked to it are not shown, since the release's checks do not confirm them.

TrialTitlePhaseParticipantsResults first postedNamed asLinked bySource
NCT02144077Safety and Efficacy Study for the Treatment of Non-Aggressive Basal Cell Carcinoma With Photodynamic TherapyPhase 32812019-03-11aminolevulinic acidIts nameClinicalTrials.gov
NCT02137785Safety and Efficacy Study of Photodynamic Therapy With Levulan Kerastick + Blue Light for Actinic Keratoses on the Upper ExtremitiesPhase 32692015-09-16aminolevulinic acidIts nameClinicalTrials.gov
NCT00706433Light Dose Ranging Study of Photodynamic Therapy (PDT) With Levulan + Blue Light Versus Vehicle + Blue Light in Severe Facial AcnePhase 22662009-08-21aminolevulinic acidIts nameClinicalTrials.gov
NCT01475955Short-incubation Levulan Photodynamic Therapy Versus Vehicle for Face/Scalp Actinic Keratosis (AK)Phase 22352013-12-24aminolevulinic acidIts nameClinicalTrials.gov
NCT03573401Study to Evaluate the Safety and Efficacy of BF-200 ALA (Ameluz®) and BF-RhodoLED® in the Treatment of Superficial Basal Cell Carcinoma (sBCC) With Photodynamic Therapy (PDT).Phase 31872025-04-29aminolevulinic acidIts nameClinicalTrials.gov
NCT00002975Photodynamic Therapy in Treating Patients With Skin CancerPhase 21802013-10-10aminolevulinic acidIts nameClinicalTrials.gov
NCT02239679Controlled Study of the Occurrence of Actinic Keratosis on the Face After Cryotherapy + Aminolevulinic Acid (ALA) Photodynamic TherapyPhase 21662017-09-21aminolevulinic acidIts nameClinicalTrials.gov
NCT02632110Microneedle Lesion Preparation Prior to Aminolevulinic Acid Photodynamic Therapy (ALA-PDT) for AK on FacePhase 21372017-12-13aminolevulinic acidIts nameClinicalTrials.gov
NCT05060237Study to Evaluate Safety and Tolerability of BF-200 ALA (Ameluz®) for Photodynamic Therapy in the Treatment of the Expanded Field of Actinic Keratosis on Face and ScalpPhase 11122024-10-17aminolevulinic acidIts nameClinicalTrials.gov
NCT01966120Safety and Efficacy Study for the Field-directed Treatment of Actinic Keratosis (AK) With Photodynamic Therapy (PDT)Phase 3872016-12-19aminolevulinic acidIts nameClinicalTrials.gov

1 to 10 of 71

See all 71 trials

Comparisons in its trials16

Comparisons Trial comparisons calculated in the trials whose record names the drug, most participants first. A comparison in one of its trials does not always compare the drug, so read the two groups.

ComparisonGroup 1, with the outcomeGroup 2, with the outcomeParticipantsTrialSource
BF-200 ALA vs Methyl-aminolevulinate: deaths from any cause0 of 1381 of 143281NCT02144077Trial comparisons
BF-200 ALA vs Methyl-aminolevulinate: serious adverse events3 of 1387 of 143281NCT02144077Trial comparisons
ALA-PDT vs Vehicle: Complete Clearance Rate42 of 13517 of 134269NCT02137785Trial comparisons
ALA-PDT vs Vehicle: Complete Clearance Rate35 of 13512 of 134269NCT02137785Trial comparisons
ALA-PDT vs Vehicle: serious adverse events5 of 1352 of 134269NCT02137785Trial comparisons
BF-200 ALA vs Vehicle: deaths from any cause0 of 1450 of 42187NCT03573401Trial comparisons
BF-200 ALA vs Vehicle: serious adverse events3 of 1452 of 42187NCT03573401Trial comparisons
BF-200 ALA vs Placebo to BF-200 ALA: serious adverse events2 of 550 of 3287NCT01966120Trial comparisons
Aminolevulinic Acid vs Vehicle: serious adverse events0 of 350 of 3570NCT01458587Trial comparisons
10-minute Incubation With Microneedle Roller & Sham vs 20-minute Incubation With Microneedle Roller & Sham: deaths from any cause0 of 160 of 1632NCT02594644Trial comparisons

Papers from its trials23

The papers the trials whose record names the drug list on ClinicalTrials.gov as their results (RESULT) or as drawn from them (DERIVED), results first, newest first.

PMIDListed asTrials listing itSource
30329163RESULT1PubMed
29432644RESULT1PubMed
28532759RESULT1PubMed
27167413RESULT1PubMed
26921093RESULT1PubMed
26300464RESULT1PubMed
25950503RESULT1PubMed
25174261RESULT1PubMed
24818175RESULT1PubMed
24589500RESULT1PubMed

Tests in its trials0

The tests ConductCognition runs that the trials whose record names the drug name in their registered outcomes, as ScienceGraph matched them. ConductCognition's list names the tests it runs, not every test a trial used.

None in this release.

Data dates

The date of each source this release read.

Open Targets
2026-09-18
Open Targets
ClinicalTrials.gov
2026-11-05
ClinicalTrials.gov
Results, from AACT
2026-03-23
AACT
Papers the trials list, from Trials
2026-11-12
Trials
Comparisons, from Trial comparisons
2026-03-23
Trial comparisons
Tests named in the trials, as ScienceGraph matched them
2026-11-12
ConductCognition

Sources 7

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ConductCognition's list of its testsOur own data
  • ClinicalTrials.govNo license stated
  • NLM's MeSHNLM's terms
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ConductCognition's list of its testsOur own data: ConductCognition's list of its tests, https://conductcognition.com
  • ClinicalTrials.govnone stated
  • NLM's MeSHNLM's
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this drug from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/drugs/v1/CHEMBL601

GET https://conductscience.org/api/drugs/v1/CHEMBL601/diseases?page=2