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Paper · 107263

The role of H-2-linked genes in helper T-cell function. VI. Expression of Ir genes by helper T cells.

Marrack P and 1 other. J Exp Med, 1979. Cited by 14 papers, by iCite.

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ConductScience Library. The role of H-2-linked genes in helper T-cell function. VI. Expression of Ir genes by helper T cells. Papers, record 107263. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/107263

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Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title
The role of H-2-linked genes in helper T-cell function. VI. Expression of Ir genes by helper T cells.
PubMed
Journal
J Exp Med
PubMed
Year
1979
PubMed
Publication types
Journal Article, Research Support, U.S. Gov't, P.H.S.
PubMed
Citations, by iCite
14
iCite
Relative citation ratio, by iCite
0.28
iCite
Revised in PubMed
2019-05-08
PubMed

Authors2

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

OrderAuthorForenameKindORCID iD
1Marrack PP
2Kappler JWJ W

Source PubMed

Topics9

NLM's MeSH indexing of the paper, its major topics first.

MeSH termMajor
Genes, MHC Class IIMajor topic
H-2 AntigensMajor topic
Lymphocyte CooperationMajor topic
T-LymphocytesMajor topic
Animals
Genetic Linkage
Mice
Peptides
Radiation Chimera

Source PubMed

Grants0

Each grant PubMed's record writes, matched to the NIH project NIH's grant and paper links name for this paper, and each of those links the record does not write.

None in this release.

Trials0

The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.

None in this release.

Comments and corrections0

PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.

None in this release.

References17

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

OrderPMIDTitleJournalYearIn PapersSource
1102,728The role of H-2 linked genes in helper T-cell function. IV. Importance of T-cell genotype and host environment in I-region and Ir gene expression.J Exp Med1978https://conductscience.org/library/papers/102728PubMed
21,085,419Helper T cells recognise antigen and macrophage surface components simultaneously.Nature1976https://conductscience.org/library/papers/1085419PubMed
3305,459On the thymus in the differentiation of "H-2 self-recognition" by T cells: evidence for dual recognition?J Exp Med1978https://conductscience.org/library/papers/305459PubMed
4305,460The lymphoreticular system in triggering virus plus self-specific cytotoxic T cells: evidence for T help.J Exp Med1978https://conductscience.org/library/papers/305460PubMed
5307,186Influence of the major histocompatibility complex on lymphocyte interactions in antibody formation.Nature1978https://conductscience.org/library/papers/307186PubMed
6307,765Major histocompatibility complex-linked immune-responsiveness is acquired by lymphocytes of low-responder mice differentiating in thymus of high-responder mice.Proc Natl Acad Sci U S A1978https://conductscience.org/library/papers/307765PubMed
7308,092Restricted helper function of F1 leads to parent bone marrow chimeras controlled by K-end of H-2 complex.J Exp Med1978https://conductscience.org/library/papers/308092PubMed
8308,986H-2 antigens of the thymus determine lymphocyte specificity.J Exp Med1978https://conductscience.org/library/papers/308986PubMed
9411,877The role of H-2-linked genes in helper T-cell function. I. In vitro expression in B cells of immune response genes controlling helper T-cell activity.J Exp Med1977https://conductscience.org/library/papers/411877PubMed
104,139,227Isolation of antigen-binding cells from unprimed mice: demonstration of antibody-forming cell precursor activity and correlation between precursor and secreted antibody avidities.J Exp Med1974https://conductscience.org/library/papers/4139227PubMed

1 to 10 of 17

See all 17 references

Cited by6

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 14 citations.

PMIDTitleJournalYearIn PapersSource
6,977,484
Genetic regulation of delayed-type hypersensitivity responses to poly (Tyr,Glu)-poly(DLAla)--poly(Lys): expression of the genetic defect in the induction and manifestation phases in H-2s and H-2f mice.
Immunology1982https://conductscience.org/library/papers/6977484PubMed
6,766,173Genetic regulation of delayed-type hypersensitivity responses to poly(LTyr,LGu)-poly(DLAla)--poly(LLys). I. Expression of the genetic defect at two phases of the immune process.J Exp Med1980https://conductscience.org/library/papers/6766173PubMed
6,455,762T cell recognition of antigen in vivo: role of the H-2 complex.Springer Semin Immunopathol1980https://conductscience.org/library/papers/6455762PubMed
6,161,877Antigen-specific T-cell factors.Immunology1980https://conductscience.org/library/papers/6161877PubMed
117,075Functional analysis of T cells expressing Ia antigens. I. Demonstration of helper T-cell heterogeneity.J Exp Med1979https://conductscience.org/library/papers/117075PubMed
92,524Continuous proliferation of murine antigen-specific helper T lymphocytes in culture.J Exp Med1979https://conductscience.org/library/papers/92524PubMed

Genes1

The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.

GeneNCBI Gene IDLinked byIn Genes
INSR3,643PubTator's text mininghttps://conductscience.org/library/genes/3643

Source NCBI Gene

Drugs0

The drugs whose trials, in the Pipelines release, list the paper.

None in this release.

Data0

The data bank entries PubMed's record names. Trial numbers are under Trials.

None in this release.

Data dates

The date of each source this release read.

PubMed
2026-11-06
PubMed
iCite
2026-11-05
iCite
PMC's ID file
2026-11-05
PMC's ID file
NIH RePORTER's grant and paper links
2026-11-01
NIH RePORTER's grant and paper links
Trials
2026-11-12
Gene search
2026-11-11
Pipelines
2026-09-18

Sources 11

  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • HGNCCC0
  • iCiteCC BY 4.0
  • NCBI GenePublic domain (US government)
  • NIH RePORTER's grant and paper linksPublic domain
  • Open TargetsCC0 1.0
  • PMC's ID filePublic domain (US government)
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • HGNCCC0: https://www.genenames.org/about/license/
  • iCiteCC BY 4.0
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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