Paper · 1374445
CD19 regulation of human B cell responses. B cell proliferation and antibody secretion are inhibited or enhanced by ligation of the CD19 surface glycoprotein depending on the stimulating signal used.
Callard RE and 4 others. J Immunol, 1992. Cited by 46 papers, by iCite.
11 sourcespapers-2026-11-12-0.1.0
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ConductScience Library. CD19 regulation of human B cell responses. B cell proliferation and antibody secretion are inhibited or enhanced by ligation of the CD19 surface glycoprotein depending on the stimulating signal used. Papers, record 1374445. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/1374445
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Paper
PubMed's record of the paper, with iCite's citation figures. No abstract is shown.
- Title
- CD19 regulation of human B cell responses. B cell proliferation and antibody secretion are inhibited or enhanced by ligation of the CD19 surface glycoprotein depending on the stimulating signal used.
- PubMed
Topics14
NLM's MeSH indexing of the paper, its major topics first.
| MeSH term | Major |
|---|---|
| Antibody Formation | Major topic |
| Antigens, CD | Major topic |
| Antigens, Differentiation, B-Lymphocyte | Major topic |
| B-Lymphocytes | Major topic |
| Lymphocyte Activation | Major topic |
| Antigens, CD19 | |
| Cell Differentiation | |
| Humans | |
| Immunoglobulin M | |
| Interleukin-4 | |
| Receptors, Antigen, B-Cell | |
| Receptors, Fc | |
| Receptors, IgE | |
| Tetradecanoylphorbol Acetate |
Source PubMed
Grants0
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None in this release.
Trials0
The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.
None in this release.
Comments and corrections0
PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.
None in this release.
References0
The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.
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Cited by14
The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 46 citations.
| PMID | Title | Journal | Year | In Papers | Source |
|---|---|---|---|---|---|
| 38,967,751 | Comparison of Non B-Ig and B-Ig. | Adv Exp Med Biol | 2024 | https://conductscience.org/library/papers/38967751 | PubMed |
| 36,407,961 | Disrupting N-Glycosylation Using Type I Mannosidase Inhibitors Alters B-Cell Receptor Signaling. | ACS Pharmacol Transl Sci | 2022 | https://conductscience.org/library/papers/36407961 | PubMed |
| 30,569,825 | Co-engaging CD47 and CD19 with a bispecific antibody abrogates B-cell receptor/CD19 association leading to impaired B-cell proliferation. | MAbs | 2019 | https://conductscience.org/library/papers/30569825 | PubMed |
| 24,828,435 | Suppression of innate and adaptive B cell activation pathways by antibody coengagement of FcγRIIb and CD19. | MAbs | 2014 | https://conductscience.org/library/papers/24828435 | PubMed |
| 18,445,007 | Identification of two subpopulations of purified human blood B cells, CD27- CD23+ and CD27high CD80+, that strongly express cell surface Toll-like receptor 9 and secrete high levels of interleukin-6. | Immunology | 2008 | https://conductscience.org/library/papers/18445007 | PubMed |
| 12,618,856 | Subversion of B lymphocyte signaling by infectious agents. | Genes Immun | 2003 | https://conductscience.org/library/papers/12618856 | PubMed |
| 11,339,363 | CD19 regulates intrinsic B lymphocyte signal transduction and activation through a novel mechanism of processive amplification. | Immunol Res | 2000 | https://conductscience.org/library/papers/11339363 | PubMed |
| 9,083,889 | A novel human monoclonal antibody rapidly induces homotypic cell aggregation and promotes antibody-secreting activity by human B lymphoblastoid cell line IM-9. | J Clin Immunol | 1997 | https://conductscience.org/library/papers/9083889 | PubMed |
| 7,690,834 | Functional dissection of the CD21/CD19/TAPA-1/Leu-13 complex of B lymphocytes. | J Exp Med | 1993 | https://conductscience.org/library/papers/7690834 | PubMed |
| 7,595,190 | Engaging CD19 or target of an antiproliferative antibody 1 on human B lymphocytes induces binding of B cells to the interfollicular stroma of human tonsils via integrin alpha 4/beta 1 and fibronectin. | J Exp Med | 1995 | https://conductscience.org/library/papers/7595190 | PubMed |
1 to 10 of 14
See all 14 cited byGenes6
The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.
| Gene | NCBI Gene ID | Linked by | In Genes | Source |
|---|---|---|---|---|
| CD19 | 930 | PubTator's text mining | https://conductscience.org/library/genes/930 | NCBI Gene |
| CD40 | 958 | PubTator's text mining | https://conductscience.org/library/genes/958 | NCBI Gene |
| FCER2 | 2,208 | PubTator's text mining | https://conductscience.org/library/genes/2208 | NCBI Gene |
| IL2 | 3,558 | PubTator's text mining | https://conductscience.org/library/genes/3558 | NCBI Gene |
| IL4 | 3,565 | PubTator's text mining | https://conductscience.org/library/genes/3565 | NCBI Gene |
| IL6 | 3,569 | PubTator's text mining | https://conductscience.org/library/genes/3569 | NCBI Gene |
Drugs0
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None in this release.
Data0
The data bank entries PubMed's record names. Trial numbers are under Trials.
None in this release.
Data dates
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- Trials
- 2026-11-12
- Gene search
- 2026-11-11
- Pipelines
- 2026-09-18
Sources 11
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- HGNCCC0
- iCiteCC BY 4.0
- NCBI GenePublic domain (US government)
- NIH RePORTER's grant and paper linksPublic domain
- Open TargetsCC0 1.0
- PMC's ID filePublic domain (US government)
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- HGNCCC0: https://www.genenames.org/about/license/
- iCiteCC BY 4.0
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
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