Paper · 18974005
Calpain 3, the "gatekeeper" of proper sarcomere assembly, turnover and maintenance.
Beckmann JS and 1 other. Neuromuscul Disord, 2008. Cited by 119 papers, by iCite.
11 sourcespapers-2026-11-12-0.1.0
Cite this record
ConductScience Library. Calpain 3, the "gatekeeper" of proper sarcomere assembly, turnover and maintenance. Papers, record 18974005. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/18974005
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Paper
PubMed's record of the paper, with iCite's citation figures. No abstract is shown.
Topics8
NLM's MeSH indexing of the paper, its major topics first.
| MeSH term | Major |
|---|---|
| Calpain | Major topic |
| Muscular Dystrophies, Limb-Girdle | Major topic |
| Sarcomeres | Major topic |
| Animals | |
| Humans | |
| Models, Biological | |
| Muscle Proteins | |
| Mutation |
Source PubMed
Grants4
Each grant PubMed's record writes, matched to the NIH project NIH's grant and paper links name for this paper, and each of those links the record does not write.
| Grant, as the record writes it | Agency | Country | NIH project | Stated by | Source |
|---|---|---|---|---|---|
| P30 AR057230 | NIAMS NIH HHS | United States | P30AR057230 | PubMed and NIH | NIH RePORTER |
| R01 AR048177 | NIAMS NIH HHS | United States | R01AR048177 | PubMed and NIH | NIH RePORTER |
| R01 AR052693 | NIAMS NIH HHS | United States | R01AR052693 | PubMed and NIH | NIH RePORTER |
| R13 AR055422 | NIAMS NIH HHS | United States | R13AR055422 | PubMed and NIH | NIH RePORTER |
Trials0
The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.
None in this release.
Comments and corrections0
PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.
None in this release.
References100
The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.
| Order | PMID | Title | Journal | Year | In Papers | Source |
|---|---|---|---|---|---|---|
| 1 | 3,275,904 | Clinical and genetic investigation in autosomal dominant limb-girdle muscular dystrophy. | Neurology | 1988 | https://conductscience.org/library/papers/3275904 | PubMed |
| 2 | 2,555,341 | Molecular cloning of a novel mammalian calcium-dependent protease distinct from both m- and mu-types. Specific expression of the mRNA in skeletal muscle. | J Biol Chem | 1989 | https://conductscience.org/library/papers/2555341 | PubMed |
| 3 | 1,901,754 | A gene for limb-girdle muscular dystrophy maps to chromosome 15 by linkage. | C R Acad Sci III | 1991 | https://conductscience.org/library/papers/1901754 | PubMed |
| 4 | 1,822,774 | Population frequencies of inherited neuromuscular diseases--a world survey. | Neuromuscul Disord | 1991 | https://conductscience.org/library/papers/1822774 | PubMed |
| 5 | 8,486,713 | Muscle-specific calpain, p94, is degraded by autolysis immediately after translation, resulting in disappearance from muscle. | J Biol Chem | 1993 | https://conductscience.org/library/papers/8486713 | PubMed |
| 6 | 7,720,071 | Mutations in the proteolytic enzyme calpain 3 cause limb-girdle muscular dystrophy type 2A. | Cell | 1995 | https://conductscience.org/library/papers/7720071 | PubMed |
| 7 | 7,580,247 | The limb-girdle muscular dystrophies--proposal for a new nomenclature. | Neuromuscul Disord | 1995 | https://conductscience.org/library/papers/7580247 | PubMed |
| 8 | 8,537,379 | Muscle-specific calpain, p94, responsible for limb girdle muscular dystrophy type 2A, associates with connectin through IS2, a p94-specific sequence. | J Biol Chem | 1995 | https://conductscience.org/library/papers/8537379 | PubMed |
| 9 | 8,624,690 | Juvenile limb-girdle muscular dystrophy. Clinical, histopathological and genetic data from a small community living in the Reunion Island. | Brain | 1996 | https://conductscience.org/library/papers/8624690 | PubMed |
| 10 | 8,817,320 | Genetic studies and molecular structures: the dystrophin associated complex. | Hum Mol Genet | 1996 | https://conductscience.org/library/papers/8817320 | PubMed |
1 to 10 of 100
See all 100 referencesCited by73
The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 119 citations.
| PMID | Title | Journal | Year | In Papers | Source |
|---|---|---|---|---|---|
| 42,725,915 | CaMKIIβ Signaling drives expression of metabolic and stress response genes in skeletal muscle, and its loss contributes to the LGMDR1 phenotype. | Hum Mol Genet | 2026 | https://conductscience.org/library/papers/42725915 | PubMed |
| 42,693,270 | A who's who of cell types in skeletal muscle. | Commun Biol | 2026 | https://conductscience.org/library/papers/42693270 | PubMed |
| 42,511,681 | Impaired Myogenic Differentiation Is a Shared Feature Across Genetic Myopathies. | Int J Mol Sci | 2026 | https://conductscience.org/library/papers/42511681 | PubMed |
| 42,467,794 | iPLA2β: A novel store-operated calcium entry modulator contributing to muscle dysfunction during denervation. | Sci Adv | 2026 | https://conductscience.org/library/papers/42467794 | PubMed |
| 42,036,386 | Synthetic estrogen and progestin effects on the myogenic program following damage in C2C12 murine myoblasts. | Physiol Rep | 2026 | https://conductscience.org/library/papers/42036386 | PubMed |
| 41,943,420 | Evaluation of quantitative muscle MRI and an intelligent phenotyping housing system as advanced phenotyping methods in a mouse model of calpain 3-deficient muscular dystrophy. | Animal Model Exp Med | 2026 | https://conductscience.org/library/papers/41943420 | PubMed |
| 41,871,765 | Progress on cell therapy for skeletal muscle disorders. | Adv Drug Deliv Rev | 2026 | https://conductscience.org/library/papers/41871765 | PubMed |
| 41,761,360 | French National Protocol for Diagnosis and Care of Calpainopathy (LGMD R1/LGMD D4): consensus guidelines for clinical practice. | Orphanet J Rare Dis | 2026 | https://conductscience.org/library/papers/41761360 | PubMed |
| 41,683,813 | Molecular Bases of Myopathies and Their Impact on Clinical Practice: Advances and Future Perspectives. | Int J Mol Sci | 2026 | https://conductscience.org/library/papers/41683813 | PubMed |
| 41,597,217 | Candidate Interaction Partners of Calpain-5 Suggest Clues to Its Involvement in Neovascular Inflammatory Vitreoretinopathy. | Cells | 2026 | https://conductscience.org/library/papers/41597217 | PubMed |
1 to 10 of 73
See all 73 cited byGenes10
The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.
| Gene | NCBI Gene ID | Linked by | In Genes | Source |
|---|---|---|---|---|
| CAPN3 | 825 | PubTator's text mining | https://conductscience.org/library/genes/825 | NCBI Gene |
| CTNNB1 | 1,499 | PubTator's text mining | https://conductscience.org/library/genes/1499 | NCBI Gene |
| FLNC | 2,318 | PubTator's text mining | https://conductscience.org/library/genes/2318 | NCBI Gene |
| HSPD1 | 3,329 | PubTator's text mining | https://conductscience.org/library/genes/3329 | NCBI Gene |
| MLC1 | 23,209 | PubTator's text mining | https://conductscience.org/library/genes/23209 | NCBI Gene |
| MYH14 | 79,784 | PubTator's text mining | https://conductscience.org/library/genes/79784 | NCBI Gene |
| MYL1 | 4,632 | PubTator's text mining | https://conductscience.org/library/genes/4632 | NCBI Gene |
| NEB | 4,703 | PubTator's text mining | https://conductscience.org/library/genes/4703 | NCBI Gene |
| SPINK5 | 11,005 | PubTator's text mining | https://conductscience.org/library/genes/11005 | NCBI Gene |
| TTN | 7,273 | PubTator's text mining | https://conductscience.org/library/genes/7273 | NCBI Gene |
Drugs0
The drugs whose trials, in the Pipelines release, list the paper.
None in this release.
Data0
The data bank entries PubMed's record names. Trial numbers are under Trials.
None in this release.
Data dates
The date of each source this release read.
- Trials
- 2026-11-12
- Gene search
- 2026-11-11
- Pipelines
- 2026-09-18
Sources 11
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- HGNCCC0
- iCiteCC BY 4.0
- NCBI GenePublic domain (US government)
- NIH RePORTER's grant and paper linksPublic domain
- Open TargetsCC0 1.0
- PMC's ID filePublic domain (US government)
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- HGNCCC0: https://www.genenames.org/about/license/
- iCiteCC BY 4.0
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
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