Paper · 30387828
UBA2 promotes proliferation of colorectal cancer.
He P and 8 others. Mol Med Rep, 2018. Cited by 23 papers, by iCite.
11 sourcespapers-2026-11-12-0.1.0
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ConductScience Library. UBA2 promotes proliferation of colorectal cancer. Papers, record 30387828. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/30387828
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Paper
PubMed's record of the paper, with iCite's citation figures. No abstract is shown.
Topics20
NLM's MeSH indexing of the paper, its major topics first.
| MeSH term | Major |
|---|---|
| Colorectal Neoplasms | Major topic |
| Ubiquitin-Activating Enzymes | Major topic |
| Adult | |
| Aged | |
| Animals | |
| Cell Cycle | |
| Cell Line, Tumor | |
| Cell Movement | |
| Cell Proliferation | |
| Disease Models, Animal | |
| Female | |
| Gene Expression | |
| Humans | |
| Male | |
| Mice | |
| Middle Aged | |
| Neoplasm Grading | |
| Neoplasm Metastasis | |
| Neoplasm Staging | |
| Prognosis |
Source PubMed
Grants0
Each grant PubMed's record writes, matched to the NIH project NIH's grant and paper links name for this paper, and each of those links the record does not write.
None in this release.
Trials0
The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.
None in this release.
Comments and corrections0
PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.
None in this release.
References39
The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.
| Order | PMID | Title | Journal | Year | In Papers | Source |
|---|---|---|---|---|---|---|
| 1 | 9,920,803 | In vitro SUMO-1 modification requires two enzymatic steps, E1 and E2. | Biochem Biophys Res Commun | 1999 | https://conductscience.org/library/papers/9920803 | PubMed |
| 2 | 18,473,732 | The PTEN/PI3K/AKT signalling pathway in cancer, therapeutic implications. | Curr Cancer Drug Targets | 2008 | https://conductscience.org/library/papers/18473732 | PubMed |
| 3 | 28,284,030 | SUMO conjugation - a mechanistic view. | Biomol Concepts | 2017 | https://conductscience.org/library/papers/28284030 | PubMed |
| 4 | 21,037,263 | starBase: a database for exploring microRNA-mRNA interaction maps from Argonaute CLIP-Seq and Degradome-Seq data. | Nucleic Acids Res | 2011 | https://conductscience.org/library/papers/21037263 | PubMed |
| 5 | 23,673,635 | SUMO2/3 modification of cyclin E contributes to the control of replication origin firing. | Nat Commun | 2013 | https://conductscience.org/library/papers/23673635 | PubMed |
| 6 | 24,297,251 | starBase v2.0: decoding miRNA-ceRNA, miRNA-ncRNA and protein-RNA interaction networks from large-scale CLIP-Seq data. | Nucleic Acids Res | 2014 | https://conductscience.org/library/papers/24297251 | PubMed |
| 7 | 25,869,096 | Functional Proteomics Study Reveals SUMOylation of TFII-I is Involved in Liver Cancer Cell Proliferation. | J Proteome Res | 2015 | https://conductscience.org/library/papers/25869096 | PubMed |
| 8 | 27,916,539 | Inhibiting the SUMO Pathway Represses the Cancer Stem Cell Population in Breast and Colorectal Carcinomas. | Stem Cell Reports | 2016 | https://conductscience.org/library/papers/27916539 | PubMed |
| 9 | 27,456,362 | Depletion of UBA protein 2-like protein inhibits growth and induces apoptosis of human colorectal carcinoma cells. | Tumour Biol | 2016 | https://conductscience.org/library/papers/27456362 | PubMed |
| 10 | 25,860,128 | Characterization of the loss of SUMO pathway function on cancer cells and tumor proliferation. | PLoS One | 2015 | https://conductscience.org/library/papers/25860128 | PubMed |
1 to 10 of 39
See all 39 referencesCited by17
The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 23 citations.
| PMID | Title | Journal | Year | In Papers | Source |
|---|---|---|---|---|---|
| 42,373,928 | UBA2: the gatekeeper of the sumoylation pathway and its multifaceted roles in human diseases and therapeutic prospects. | Clin Exp Med | 2026 | https://conductscience.org/library/papers/42373928 | PubMed |
| 40,918,458 | MYH11 Suppresses Colorectal Cancer Progression by Inhibiting Epithelial-Mesenchymal Transition via ZEB1 Regulation. | Oncol Res | 2025 | https://conductscience.org/library/papers/40918458 | PubMed |
| 40,741,192 | Molecular mechanisms of thymopoietin in papillary thyroid cancer: Multiplatform gene expression data, gene knockout screening, and in-house immunohistochemistry. | World J Clin Oncol | 2025 | https://conductscience.org/library/papers/40741192 | PubMed |
| 37,777,749 | Role of non-canonical post-translational modifications in gastrointestinal tumors. | Cancer Cell Int | 2023 | https://conductscience.org/library/papers/37777749 | PubMed |
| 37,056,932 | IGF2BP3 Regulates TMA7-mediated Autophagy and Cisplatin Resistance in Laryngeal Cancer via m6A RNA Methylation. | Int J Biol Sci | 2023 | https://conductscience.org/library/papers/37056932 | PubMed |
| 36,388,702 | Nestin protein affects the maintenance of stem characteristics of colorectal cancer cells based on p53 dependent pathway. | J Gastrointest Oncol | 2022 | https://conductscience.org/library/papers/36388702 | PubMed |
| 35,992,817 | Clinical and molecular evaluation of patients with ovarian cancer in the context of drug resistance to chemotherapy. | Front Oncol | 2022 | https://conductscience.org/library/papers/35992817 | PubMed |
| 35,859,792 | Bioinformatics-based analysis of SUMOylation-related genes in hepatocellular carcinoma reveals a role of upregulated SAE1 in promoting cell proliferation. | Open Med (Wars) | 2022 | https://conductscience.org/library/papers/35859792 | PubMed |
| 35,661,832 | circXRCC5 foster gastric cancer growth and metastasis by the HNRNPC/circXRCC5/miR-655-3p/RREB1/UBA2 positive feedback loop. | Cancer Gene Ther | 2022 | https://conductscience.org/library/papers/35661832 | PubMed |
| 34,930,905 | WTIP upregulates FOXO3a and induces apoptosis through PUMA in acute myeloid leukemia. | Cell Death Dis | 2021 | https://conductscience.org/library/papers/34930905 | PubMed |
1 to 10 of 17
See all 17 cited byGenes24
The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.
| Gene | NCBI Gene ID | Linked by | In Genes | Source |
|---|---|---|---|---|
| AKT1 | 207 | PubTator's text mining | https://conductscience.org/library/genes/207 | NCBI Gene |
| AKT1S1 | 84,335 | PubTator's text mining | https://conductscience.org/library/genes/84335 | NCBI Gene |
| ANXA5 | 308 | PubTator's text mining | https://conductscience.org/library/genes/308 | NCBI Gene |
| APOBEC3G | 60,489 | PubTator's text mining | https://conductscience.org/library/genes/60489 | NCBI Gene |
| BAX | 581 | PubTator's text mining | https://conductscience.org/library/genes/581 | NCBI Gene |
| BCL2 | 596 | PubTator's text mining | https://conductscience.org/library/genes/596 | NCBI Gene |
| CASP3 | 836 | PubTator's text mining | https://conductscience.org/library/genes/836 | NCBI Gene |
| CCNB1 | 891 | PubTator's text mining | https://conductscience.org/library/genes/891 | NCBI Gene |
| CDK6 | 1,021 | PubTator's text mining | https://conductscience.org/library/genes/1021 | NCBI Gene |
| DCTN6 | 10,671 | PubTator's text mining | https://conductscience.org/library/genes/10671 | NCBI Gene |
1 to 10 of 24
See all 24 genesDrugs0
The drugs whose trials, in the Pipelines release, list the paper.
None in this release.
Data0
The data bank entries PubMed's record names. Trial numbers are under Trials.
None in this release.
Data dates
The date of each source this release read.
- Trials
- 2026-11-12
- Gene search
- 2026-11-11
- Pipelines
- 2026-09-18
Sources 11
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- HGNCCC0
- iCiteCC BY 4.0
- NCBI GenePublic domain (US government)
- NIH RePORTER's grant and paper linksPublic domain
- Open TargetsCC0 1.0
- PMC's ID filePublic domain (US government)
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- HGNCCC0: https://www.genenames.org/about/license/
- iCiteCC BY 4.0
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
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