ConductScience.org, home
Papers
API referenceFor AI assistants

Paper · 31160587

Tumour-associated macrophages exhibit anti-tumoural properties in Sonic Hedgehog medulloblastoma.

Maximov V and 11 others. Nat Commun, 2019. Cited by 93 papers, by iCite.

11 sourcespapers-2026-11-12-0.1.0

Download JSON
Cite this record

ConductScience Library. Tumour-associated macrophages exhibit anti-tumoural properties in Sonic Hedgehog medulloblastoma. Papers, record 31160587. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/31160587

On this page

Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title
Tumour-associated macrophages exhibit anti-tumoural properties in Sonic Hedgehog medulloblastoma.
PubMed
Journal
Nat Commun
PubMed
Year
2019
PubMed
Publication types
Journal Article, Research Support, N.I.H., Extramural, Research Support, Non-U.S. Gov't
PubMed
Citations, by iCite
93
iCite
Relative citation ratio, by iCite
3.12
iCite
Revised in PubMed
2026-01-27
PubMed

Authors12

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

OrderAuthorForenameKindORCID iD
1Maximov VVictor
2Chen ZZhihong
3Wei YYun
4Robinson MHM Hope
5Herting CJCameron J
6Shanmugam NSNithya S
7Rudneva VAVasilisa Ahttps://orcid.org/0000-0002-4340-9311
8Goldsmith KCKelly C
9MacDonald TJTobey J
10Northcott PAPaul A

1 to 10 of 12Source PubMed

See all 12 authors

Topics21

NLM's MeSH indexing of the paper, its major topics first.

MeSH termMajor
Cerebellar NeoplasmsMajor topic
MacrophagesMajor topic
MedulloblastomaMajor topic
Tumor MicroenvironmentMajor topic
Animals
Antigens, CD
Antigens, Differentiation, Myelomonocytic
CD11b Antigen
Calcium-Binding Proteins
Chemokine CCL2
DNA-Binding Proteins
Disease Models, Animal
Hedgehog Proteins
Humans
Mice
Microfilament Proteins
Microglia
Myeloid Cells
Receptors, CCR2
Up-Regulation
CD68 Molecule

Source PubMed

Grants7

Each grant PubMed's record writes, matched to the NIH project NIH's grant and paper links name for this paper, and each of those links the record does not write.

Grant, as the record writes itAgencyCountryNIH projectStated bySource
T32 GM008602NIGMS NIH HHSUnited StatesT32GM008602PubMed and NIHNIH RePORTER
R01 NS100864NINDS NIH HHSUnited StatesR01NS100864PubMedNIH RePORTER
R01 NS061070NINDS NIH HHSUnited StatesR01NS061070PubMedNIH RePORTER
U01 CA160882NCI NIH HHSUnited StatesU01CA160882PubMed and NIHNIH RePORTER
F31 NS106887NINDS NIH HHSUnited StatesF31NS106887PubMed and NIHNIH RePORTER
P30 CA138292NCI NIH HHSUnited StatesP30CA138292PubMed and NIHNIH RePORTER
R01CA100864NIHNIH RePORTER

Trials0

The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.

None in this release.

Comments and corrections0

PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.

None in this release.

References34

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

OrderPMIDTitleJournalYearIn PapersSource
121,376,230Hallmarks of cancer: the next generation.Cell2011https://conductscience.org/library/papers/21376230PubMed
228,099,414Neurotoxic reactive astrocytes are induced by activated microglia.Nature2017https://conductscience.org/library/papers/28099414PubMed
312,915,300Math1-driven GFP expression in the developing nervous system of transgenic mice.Gene Expr Patterns2003https://conductscience.org/library/papers/12915300PubMed
415,034,056Subpopulations of mouse blood monocytes differ in maturation stage and inflammatory response.J Immunol2004https://conductscience.org/library/papers/15034056PubMed
528,726,821The whole-genome landscape of medulloblastoma subtypes.Nature2017https://conductscience.org/library/papers/28726821PubMed
624,056,773CSF-1R inhibition alters macrophage polarization and blocks glioma progression.Nat Med2013https://conductscience.org/library/papers/24056773PubMed
724,078,694Characterization of distinct immunophenotypes across pediatric brain tumor types.J Immunol2013https://conductscience.org/library/papers/24078694PubMed
827,530,322CCL2 Produced by the Glioma Microenvironment Is Essential for the Recruitment of Regulatory T Cells and Myeloid-Derived Suppressor Cells.Cancer Res2016https://conductscience.org/library/papers/27530322PubMed
917,981,560Macrophage activation and polarization.Front Biosci2008https://conductscience.org/library/papers/17981560PubMed
1011,287,620Generation and analysis of mice lacking the chemokine fractalkine.Mol Cell Biol2001https://conductscience.org/library/papers/11287620PubMed

1 to 10 of 34

See all 34 references

Cited by77

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 93 citations.

PMIDTitleJournalYearIn PapersSource
42,683,289The tumor microenvironment of medulloblastoma: from emerging biological insights to novel therapeutic targeting.Front Oncol2026https://conductscience.org/library/papers/42683289PubMed
42,180,054Immune checkpoint inhibitors in medulloblastoma: current updates in preclinical and clinical developments.Front Oncol2026https://conductscience.org/library/papers/42180054PubMed
42,051,512Decoding the immune microenvironment: precision immunotherapy for medulloblastoma subtypes.Front Immunol2026https://conductscience.org/library/papers/42051512PubMed
41,993,485
Myeloid compartment reprogramming through nanoparticle-delivered resiquimod blocks paracrine growth support and activates phagocytosis to slow tumor progression in endogenous mouse medulloblastoma and diffuse midline glioma models.
bioRxiv2026https://conductscience.org/library/papers/41993485PubMed
41,757,579Nested ecosystems theory for conceptualizing brain tumors.Dis Model Mech2026https://conductscience.org/library/papers/41757579PubMed
41,602,819Exploring the prognostic molecular mechanisms of medulloblastoma through methylation-transcriptome integration.SAGE Open Med2026https://conductscience.org/library/papers/41602819PubMed
41,278,839REST elevation-dependent chromatin remodeling and alternative Grk6 transcript synthesis hyperactivates Cxcr4-Sdf1 signaling in cerebellar granule cell progenitors.bioRxiv2025https://conductscience.org/library/papers/41278839PubMed
41,122,966Improving immunotherapy responses by dual inhibition of macrophage migration inhibitory factor and PD-1.JCI Insight2025https://conductscience.org/library/papers/41122966PubMed
40,867,227Advancing Medulloblastoma Therapy in Pediatrics: Integrative Molecular Classification and Emerging Treatments.Brain Sci2025https://conductscience.org/library/papers/40867227PubMed
40,805,120NRP1 and GFAP Expression in the Medulloblastoma Microenvironment: Implications for Angiogenesis and Tumor Progression.Cancers (Basel)2025https://conductscience.org/library/papers/40805120PubMed

1 to 10 of 77

See all 77 cited by

Genes10

The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.

GeneNCBI Gene IDLinked byIn GenesSource
AIF1199PubTator's text mininghttps://conductscience.org/library/genes/199NCBI Gene
CCL26,347PubTator's text mininghttps://conductscience.org/library/genes/6347NCBI Gene
CCR2729,230PubTator's text mininghttps://conductscience.org/library/genes/729230NCBI Gene
CD68968PubTator's text mininghttps://conductscience.org/library/genes/968NCBI Gene
CX3CR11,524PubTator's text mininghttps://conductscience.org/library/genes/1524NCBI Gene
ITGAM3,684PubTator's text mininghttps://conductscience.org/library/genes/3684NCBI Gene
NEUROD24,761PubTator's text mininghttps://conductscience.org/library/genes/4761NCBI Gene
PECAM15,175PubTator's text mininghttps://conductscience.org/library/genes/5175NCBI Gene
PTPRC5,788PubTator's text mininghttps://conductscience.org/library/genes/5788NCBI Gene
SHH6,469PubTator's text mininghttps://conductscience.org/library/genes/6469NCBI Gene

Drugs0

The drugs whose trials, in the Pipelines release, list the paper.

None in this release.

Data0

The data bank entries PubMed's record names. Trial numbers are under Trials.

None in this release.

Data dates

The date of each source this release read.

PubMed
2026-11-06
PubMed
iCite
2026-11-05
iCite
PMC's ID file
2026-11-05
PMC's ID file
NIH RePORTER's grant and paper links
2026-11-01
NIH RePORTER's grant and paper links
Trials
2026-11-12
Gene search
2026-11-11
Pipelines
2026-09-18

Sources 11

  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • HGNCCC0
  • iCiteCC BY 4.0
  • NCBI GenePublic domain (US government)
  • NIH RePORTER's grant and paper linksPublic domain
  • Open TargetsCC0 1.0
  • PMC's ID filePublic domain (US government)
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • HGNCCC0: https://www.genenames.org/about/license/
  • iCiteCC BY 4.0
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this paper from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/papers/v1/31160587

GET https://conductscience.org/api/papers/v1/31160587/references?page=2

API referenceFor AI assistants