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Paper · 314490

Thymic reconstitution of nude F1 mice with one or both parental thymus grafts.

Zinkernagel RM and 2 others. J Exp Med, 1979. Cited by 37 papers, by iCite.

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ConductScience Library. Thymic reconstitution of nude F1 mice with one or both parental thymus grafts. Papers, record 314490. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/314490

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Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title
Thymic reconstitution of nude F1 mice with one or both parental thymus grafts.
PubMed
Journal
J Exp Med
PubMed
Year
1979
PubMed
Publication types
Journal Article, Research Support, U.S. Gov't, P.H.S.
PubMed
Citations, by iCite
37
iCite
Relative citation ratio, by iCite
0.75
iCite
Revised in PubMed
2021-12-03
PubMed

Authors3

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

OrderAuthorForenameKindORCID iD
1Zinkernagel RMR M
2Althage AA
3Callahan GG

Source PubMed

Topics14

NLM's MeSH indexing of the paper, its major topics first.

MeSH termMajor
Cytotoxicity, ImmunologicMajor topic
T-LymphocytesMajor topic
Thymus GlandMajor topic
Animals
Chimera
Female
H-2 Antigens
Immunosuppression Therapy
In Vitro Techniques
Male
Mice
Mice, Inbred Strains
Mice, Nude
Transplantation, Homologous

Source PubMed

Grants0

Each grant PubMed's record writes, matched to the NIH project NIH's grant and paper links name for this paper, and each of those links the record does not write.

None in this release.

Trials0

The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.

None in this release.

Comments and corrections0

PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.

None in this release.

References16

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

OrderPMIDTitleJournalYearIn PapersSource
178,955T-cell populations specifically depleted of alloreactive potential cannot be induced to lyse H-2-different virus-infected target cells.J Exp Med1978https://conductscience.org/library/papers/78955PubMed
283,701Thymus and lymphohemopoietic cells: their role in T cell maturation in selection of T cells' H-2-restriction-specificity and in H-2 linked Ir gene control.Immunol Rev1978https://conductscience.org/library/papers/83701PubMed
378,964In a fully H-2 incompatible chimera, T cells of donor origin can respond to minor histocompatibility antigens in association with either donor or host H-2 type.J Exp Med1978https://conductscience.org/library/papers/78964PubMed
4216,768Primary anti-viral cytotoxic T-cell responses in semiallogeneic chimeras are not absolutely restricted to host H-2 type.J Exp Med1979https://conductscience.org/library/papers/216768PubMed
5185,298Characterization of Ia antigens in mouse serum.J Immunol1976https://conductscience.org/library/papers/185298PubMed
6141,046Killer cells reactive to altered-self antigens can also be alloreactive.Proc Natl Acad Sci U S A1977https://conductscience.org/library/papers/141046PubMed
7100,570In irradiation chimeras, K or D regions of the chimeric host, not of the donor lymphocytes, determine immune responsiveness of antiviral cytotoxic T cells.J Exp Med1978https://conductscience.org/library/papers/100570PubMed
8105,404Influence of thymus genotype on acquisition of responsiveness in delayed-type hypersensitivity.Scand J Immunol1979https://conductscience.org/library/papers/105404PubMed
9305,459On the thymus in the differentiation of "H-2 self-recognition" by T cells: evidence for dual recognition?J Exp Med1978https://conductscience.org/library/papers/305459PubMed
10310,857Vaccinia-specific cytotoxic T-cell responses in the context of H-2 antigens not encountered in thymus may reflect aberrant recognition of a virus-H-2 complex.J Exp Med1979https://conductscience.org/library/papers/310857PubMed

Cited by10

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 37 citations.

PMIDTitleJournalYearIn PapersSource
10,393,953On the role of thymic epithelium vs. bone marrow-derived cells in repertoire selection of T cells.Proc Natl Acad Sci U S A1999https://conductscience.org/library/papers/10393953PubMed
8,436,912The concurrent maturation of mouse and human thymocytes in human fetal thymus implanted in NIH-beige-nude-xid mice is associated with the reconstitution of the murine immune system.J Exp Med1993https://conductscience.org/library/papers/8436912PubMed
6,976,417Tthyd, a new thymocyte alloantigen linked to Igh-1. Implications for a switch mechanism for T cell antigen receptors.J Exp Med1982https://conductscience.org/library/papers/6976417PubMed
6,967,859Use of H-2 mutations to quantitate alloreactivity: Alloreactivity is strongest against H-2 antigens which are closet to self.Immunogenetics1980https://conductscience.org/library/papers/6967859PubMed
6,965,398Restriction specificities, alloreactivity, and allotolerance expressed by T cells from nude mice reconstituted with H-2-compatible or -incompatible thymus grafts.J Exp Med1980https://conductscience.org/library/papers/6965398PubMed
6,770,025Gene complementation. Neither Ir-GLphi gene need be present in the proliferative T cell to generate an immune response to Poly(Glu55Lys36Phe9)n.J Exp Med1980https://conductscience.org/library/papers/6770025PubMed
6,402,446Thymic reconstitution of H-2-linked T-cell responses to thyroglobulin or insulin.Immunogenetics1983https://conductscience.org/library/papers/6402446PubMed
6,256,466Sendai virus-specific, H-2-restricted cytotoxic T lymphocyte responses of nude mice grafted with allogeneic or semi-allogeneic thymus glands.J Exp Med1980https://conductscience.org/library/papers/6256466PubMed
6,165,797
Antigen-reactive T cell clones. II. Unique homozygous and (high responder x low responder)F1 hybrid antigen-presenting determinants detected using poly(Tyr, Glu)-poly D, L-Ala--poly Lys-reactive T cell clones.
J Exp Med1981https://conductscience.org/library/papers/6165797PubMed
113,479Genetic control of the immune response to collagen. II. Antibody responses produced in fetal liver restored radiation chimeras and thymus reconstituted F1 hybrid nude mice.J Exp Med1979https://conductscience.org/library/papers/113479PubMed

Genes0

The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.

None in this release.

Drugs0

The drugs whose trials, in the Pipelines release, list the paper.

None in this release.

Data0

The data bank entries PubMed's record names. Trial numbers are under Trials.

None in this release.

Data dates

The date of each source this release read.

PubMed
2026-11-06
PubMed
iCite
2026-11-05
iCite
PMC's ID file
2026-11-05
PMC's ID file
NIH RePORTER's grant and paper links
2026-11-01
NIH RePORTER's grant and paper links
Trials
2026-11-12
Gene search
2026-11-11
Pipelines
2026-09-18

Sources 11

  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • HGNCCC0
  • iCiteCC BY 4.0
  • NCBI GenePublic domain (US government)
  • NIH RePORTER's grant and paper linksPublic domain
  • Open TargetsCC0 1.0
  • PMC's ID filePublic domain (US government)
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • HGNCCC0: https://www.genenames.org/about/license/
  • iCiteCC BY 4.0
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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