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Paper · 32053992

Dynamics of Salivary Gland AQP5 under Normal and Pathologic Conditions.

Hosoi K and 4 others. Int J Mol Sci, 2020. Cited by 57 papers, by iCite.

11 sourcespapers-2026-11-12-0.1.0

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ConductScience Library. Dynamics of Salivary Gland AQP5 under Normal and Pathologic Conditions. Papers, record 32053992. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/32053992

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Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title
Dynamics of Salivary Gland AQP5 under Normal and Pathologic Conditions.
PubMed
Journal
Int J Mol Sci
PubMed
Year
2020
PubMed
Publication types
Journal Article, Review
PubMed
Citations, by iCite
57
iCite
Relative citation ratio, by iCite
3.53
iCite
Revised in PubMed
2020-11-20
PubMed

Authors5

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

OrderAuthorForenameKindORCID iD
1Hosoi KKazuo
2Yao CChenjuan
3Hasegawa TTakahiro
4Yoshimura HHiroshi
5Akamatsu TTetsuya

Source PubMed

Topics9

NLM's MeSH indexing of the paper, its major topics first.

MeSH termMajor
Aquaporin 5Major topic
Salivary GlandsMajor topic
Animals
Gene Expression Regulation
Humans
Phosphorylation
Protein Processing, Post-Translational
Salivary Gland Diseases
Ubiquitination

Source PubMed

Grants1

Each grant PubMed's record writes, matched to the NIH project NIH's grant and paper links name for this paper, and each of those links the record does not write.

Grant, as the record writes itAgencyCountryNIH projectStated by
Grant-in-Aid for Scientific Research (B)(18390493), (C2)(10049413, 13671940), (C)(23592736, 23592737),Grant-in-Aid for Young Scientists (B)(16791126, 18791369, 20791353, 19770054, 21791806, 23792124)the Ministry of Education, Culture, Sports, Science, and Technology of Japan.PubMed

Source PubMed

Trials0

The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.

None in this release.

Comments and corrections0

PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.

None in this release.

References77

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

OrderPMIDTitleJournalYearIn PapersSource
125,843,887Salivary gland homeostasis is maintained through acinar cell self-duplication.Dev Cell2015https://conductscience.org/library/papers/25843887PubMed
212,783,871Cyclic AMP regulates aquaporin 5 expression at both transcriptional and post-transcriptional levels through a protein kinase A pathway.J Biol Chem2003https://conductscience.org/library/papers/12783871PubMed
316,423,834Tissue kallikrein mK13 is a candidate processing enzyme for the precursor of interleukin-1beta in the submandibular gland of mice.J Biol Chem2006https://conductscience.org/library/papers/16423834PubMed
421,868,636Induction of Sca-1 via activation of STAT3 system in the duct cells of the mouse submandibular gland by ligation of the main excretory duct.Am J Physiol Gastrointest Liver Physiol2011https://conductscience.org/library/papers/21868636PubMed
526,365,508Beyond water homeostasis: Diverse functional roles of mammalian aquaporins.Biochim Biophys Acta2015https://conductscience.org/library/papers/26365508PubMed
630,587,691Distribution of aquaporin-5, transforming growth factor-β1 and laminin during regeneration of atrophic rat submandibular glands after duct ligation.J Oral Sci2018https://conductscience.org/library/papers/30587691PubMed
78,105,741Principles of saliva secretion.Ann N Y Acad Sci1993https://conductscience.org/library/papers/8105741PubMed
827,345,595PACAP suppresses dry eye signs by stimulating tear secretion.Nat Commun2016https://conductscience.org/library/papers/27345595PubMed
918,450,949Degradation of submandibular gland AQP5 by parasympathetic denervation of chorda tympani and its recovery by cevimeline, an M3 muscarinic receptor agonist.Am J Physiol Gastrointest Liver Physiol2008https://conductscience.org/library/papers/18450949PubMed
1012,563,300Innate immune sensing and its roots: the story of endotoxin.Nat Rev Immunol2003https://conductscience.org/library/papers/12563300PubMed

1 to 10 of 77

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Cited by36

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 57 citations.

PMIDTitleJournalYearIn PapersSource
42,333,009Microbial Fermentation Reduces Xerostomia-Related 5-Demethylnobiletin in Aurantii Fructus: A Chromatographic and Pharmacological Evaluation.Biomed Chromatogr2026https://conductscience.org/library/papers/42333009PubMed
41,826,647NRIP1 disrupts ERα signal in Sjögren's disease via AQP5 suppression and MYC-driven salivary dysfunction.Exp Mol Med2026https://conductscience.org/library/papers/41826647PubMed
41,732,377Microfluidic-based oral mucoadhesive nanozyme microspheres for immune modulation of xerostomia.Mater Today Bio2026https://conductscience.org/library/papers/41732377PubMed
41,407,191Molecular signatures and signaling interactions of the hair follicle stem cell niche.J Invest Dermatol2026https://conductscience.org/library/papers/41407191PubMed
41,322,133Engineered nanozyme immunomodulator for xerostomia treatment via regulating submandibular salivary gland.Mater Today Bio2025https://conductscience.org/library/papers/41322133PubMed
41,184,862CLIP2: a novel functional player in AQP5 trafficking dynamics and implications for Sjögren's disease.Cell Commun Signal2025https://conductscience.org/library/papers/41184862PubMed
40,924,257Role of Mesenchymal Stem Cell Exosomes and Injectable Platelet Rich Fibrin on Structure and Function of Submandibular Salivary Gland of Aged Albino Rats.Saudi Dent J2025https://conductscience.org/library/papers/40924257PubMed
40,725,460Aquaporin mRNA in Human Saliva.Genes (Basel)2025https://conductscience.org/library/papers/40725460PubMed
40,005,360Saliva as a Diagnostic Tool for Systemic Diseases-A Narrative Review.Medicina (Kaunas)2025https://conductscience.org/library/papers/40005360PubMed
39,269,669Metformin Attenuates Partial Epithelial-Mesenchymal Transition in Salivary Gland Inflammation via PI3K/Akt/GSK3β/Snail Signaling Axis.Inflammation2025https://conductscience.org/library/papers/39269669PubMed

1 to 10 of 36

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Genes11

The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.

GeneNCBI Gene IDLinked byIn GenesSource
AQP2359PubTator's text mininghttps://conductscience.org/library/genes/359NCBI Gene
AQP4361PubTator's text mininghttps://conductscience.org/library/genes/361NCBI Gene
AQP5362PubTator's text mininghttps://conductscience.org/library/genes/362NCBI Gene
AVP551PubTator's text mininghttps://conductscience.org/library/genes/551NCBI Gene
JUNB3,726PubTator's text mininghttps://conductscience.org/library/genes/3726NCBI Gene
MAPK15,594PubTator's text mininghttps://conductscience.org/library/genes/5594NCBI Gene
MAPK141,432PubTator's text mininghttps://conductscience.org/library/genes/1432NCBI Gene
MAPK85,599PubTator's text mininghttps://conductscience.org/library/genes/5599NCBI Gene
NFKB14,790PubTator's text mininghttps://conductscience.org/library/genes/4790NCBI Gene
PCSK65,046PubTator's text mininghttps://conductscience.org/library/genes/5046NCBI Gene

1 to 10 of 11

See all 11 genes

Drugs0

The drugs whose trials, in the Pipelines release, list the paper.

None in this release.

Data0

The data bank entries PubMed's record names. Trial numbers are under Trials.

None in this release.

Data dates

The date of each source this release read.

PubMed
2026-11-06
PubMed
iCite
2026-11-05
iCite
PMC's ID file
2026-11-05
PMC's ID file
NIH RePORTER's grant and paper links
2026-11-01
NIH RePORTER's grant and paper links
Trials
2026-11-12
Gene search
2026-11-11
Pipelines
2026-09-18

Sources 11

  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • HGNCCC0
  • iCiteCC BY 4.0
  • NCBI GenePublic domain (US government)
  • NIH RePORTER's grant and paper linksPublic domain
  • Open TargetsCC0 1.0
  • PMC's ID filePublic domain (US government)
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • HGNCCC0: https://www.genenames.org/about/license/
  • iCiteCC BY 4.0
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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