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Paper · 35552175

Kynurenine-PARP-1 Link Mediated by MicroRNA 210 May Be Dysregulated in Pulmonary Hypertension.

Akgün AE and 4 others. Anatol J Cardiol, 2022. Cited by 3 papers, by iCite.

11 sourcespapers-2026-11-12-0.1.0

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ConductScience Library. Kynurenine-PARP-1 Link Mediated by MicroRNA 210 May Be Dysregulated in Pulmonary Hypertension. Papers, record 35552175. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/35552175

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Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title
Kynurenine-PARP-1 Link Mediated by MicroRNA 210 May Be Dysregulated in Pulmonary Hypertension.
PubMed
Journal
Anatol J Cardiol
PubMed
Year
2022
PubMed
Publication types
Journal Article
PubMed
Citations, by iCite
3
iCite
Relative citation ratio, by iCite
0.29
iCite
Revised in PubMed
2022-08-27
PubMed

Authors5

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

OrderAuthorForenameKindORCID iD
1Akgün AEAlperen Emre
2Yaylalı YTYalın Tolga
3Seçme MMücahit
4Dodurga YYavuz
5Şenol HHande

Source PubMed

Topics11

NLM's MeSH indexing of the paper, its major topics first.

MeSH termMajor
Hypertension, PulmonaryMajor topic
KynurenineMajor topic
MicroRNAsMajor topic
Adenosine Diphosphate Ribose
Apelin
Humans
Hypoxia
Poly(ADP-ribose) Polymerase Inhibitors
Poly(ADP-ribose) Polymerases
Prospective Studies
RNA, Messenger

Source PubMed

Grants0

Each grant PubMed's record writes, matched to the NIH project NIH's grant and paper links name for this paper, and each of those links the record does not write.

None in this release.

Trials0

The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.

None in this release.

Comments and corrections0

PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.

None in this release.

References16

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

OrderPMIDTitleJournalYearIn PapersSource
125,044,272MKP-1 is a target of miR-210 and mediate the negative regulation of miR-210 inhibitor on hypoxic hPASMC proliferation.Cell Biol Int2015https://conductscience.org/library/papers/25044272PubMed
224,270,264Role for DNA damage signaling in pulmonary arterial hypertension.Circulation2014https://conductscience.org/library/papers/24270264PubMed
327,591,245Update on novel targets and potential treatment avenues in pulmonary hypertension.Am J Physiol Lung Cell Mol Physiol2016https://conductscience.org/library/papers/27591245PubMed
431,952,319Challenges in Using Circulating Micro-RNAs as Biomarkers for Cardiovascular Diseases.Int J Mol Sci2020https://conductscience.org/library/papers/31952319PubMed
527,912,147Inhibition of endocan attenuates monocrotaline-induced connective tissue disease related pulmonary arterial hypertension.Int Immunopharmacol2017https://conductscience.org/library/papers/27912147PubMed
624,608,803Apelin-APJ signaling: a potential therapeutic target for pulmonary arterial hypertension.Mol Cells2014https://conductscience.org/library/papers/24608803PubMed
725,505,270The microRNA-130/301 family controls vasoconstriction in pulmonary hypertension.J Biol Chem2015https://conductscience.org/library/papers/25505270PubMed
829,877,320miRNAS in cardiovascular diseases: potential biomarkers, therapeutic targets and challenges.Acta Pharmacol Sin2018https://conductscience.org/library/papers/29877320PubMed
922,886,504miR-210 has an antiapoptotic effect in pulmonary artery smooth muscle cells during hypoxia.Am J Physiol Lung Cell Mol Physiol2012https://conductscience.org/library/papers/22886504PubMed
1023,263,626An endothelial apelin-FGF link mediated by miR-424 and miR-503 is disrupted in pulmonary arterial hypertension.Nat Med2013https://conductscience.org/library/papers/23263626PubMed

1 to 10 of 16

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Cited by3

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 3 citations.

PMIDTitleJournalYearIn PapersSource
42,846,778Tryptophan metabolism: a potential link between the gut microbiota and pulmonary vascular remodeling in pulmonary hypertension.Front Cell Infect Microbiol2026https://conductscience.org/library/papers/42846778PubMed
41,709,969Macrophage Hypoxia Signaling Pathways and Their Roles in Sepsis.J Inflamm Res2026https://conductscience.org/library/papers/41709969PubMed
39,752,011The molecular mechanism of gemcitabine in inhibiting the HIF-1α/VEGFB/FGF2/FGFR1 signaling pathway for ovarian cancer treatment.Discov Oncol2025https://conductscience.org/library/papers/39752011PubMed

Genes16

The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.

GeneNCBI Gene IDLinked byIn GenesSource
APLN8,862PubTator's text mininghttps://conductscience.org/library/genes/8862NCBI Gene
EDN11,906PubTator's text mininghttps://conductscience.org/library/genes/1906NCBI Gene
EPAS12,034PubTator's text mininghttps://conductscience.org/library/genes/2034NCBI Gene
ESM111,082PubTator's text mininghttps://conductscience.org/library/genes/11082NCBI Gene
FGF22,247PubTator's text mininghttps://conductscience.org/library/genes/2247NCBI Gene
FGFR12,260PubTator's text mininghttps://conductscience.org/library/genes/2260NCBI Gene
HIF1A3,091PubTator's text mininghttps://conductscience.org/library/genes/3091NCBI Gene
MIR130A406,919PubTator's text mininghttps://conductscience.org/library/genes/406919NCBI Gene
MIR204406,987PubTator's text mininghttps://conductscience.org/library/genes/406987NCBI Gene
MIR210406,992PubTator's text mininghttps://conductscience.org/library/genes/406992NCBI Gene

1 to 10 of 16

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Drugs0

The drugs whose trials, in the Pipelines release, list the paper.

None in this release.

Data0

The data bank entries PubMed's record names. Trial numbers are under Trials.

None in this release.

Data dates

The date of each source this release read.

PubMed
2026-11-06
PubMed
iCite
2026-11-05
iCite
PMC's ID file
2026-11-05
PMC's ID file
NIH RePORTER's grant and paper links
2026-11-01
NIH RePORTER's grant and paper links
Trials
2026-11-12
Gene search
2026-11-11
Pipelines
2026-09-18

Sources 11

  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • HGNCCC0
  • iCiteCC BY 4.0
  • NCBI GenePublic domain (US government)
  • NIH RePORTER's grant and paper linksPublic domain
  • Open TargetsCC0 1.0
  • PMC's ID filePublic domain (US government)
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • HGNCCC0: https://www.genenames.org/about/license/
  • iCiteCC BY 4.0
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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