Paper · 418135

In vitro analysis of allogeneic lymphocyte interaction. II. I-region control of the activity of a B-cell-derived H-2-restricted allogeneic effect factor and its receptor during B-cell activation.

Delovitch TL and 2 others. J Exp Med, 1978. Cited by 27 papers, by iCite.

11 sourcespapers-2026-11-12-0.1.0

Cite this record

ConductScience Library. In vitro analysis of allogeneic lymphocyte interaction. II. I-region control of the activity of a B-cell-derived H-2-restricted allogeneic effect factor and its receptor during B-cell activation. Papers, record 418135. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/418135

On this page

Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title: In vitro analysis of allogeneic lymphocyte interaction. II. I-region control of the activity of a B-cell-derived H-2-restricted allogeneic effect factor and its receptor during B-cell activation.; PubMed
Journal: J Exp Med; PubMed
Year: 1978; PubMed
Publication types: Journal Article; PubMed
PubMed: https://pubmed.ncbi.nlm.nih.gov/418135/; PubMed
DOI: https://doi.org/10.1084/jem.147.4.1198; PubMed
PMC: https://pmc.ncbi.nlm.nih.gov/articles/PMC2184251/; PubMed
The journal: https://conductscience.org/library/journal-index/2985109R; PubMed
Citations, by iCite: 27; iCite
Relative citation ratio, by iCite: 0.6; iCite
Revised in PubMed: 2019-05-08; PubMed

Authors3

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

Order	Author	Forename
1	Delovitch TL	T L
2	Biggin J	J
3	Fung FY	F Y

Source PubMed

Topics14

NLM's MeSH indexing of the paper, its major topics first.

MeSH term	Major
B-Lymphocytes	Major topic
Genes, MHC Class II	Major topic
H-2 Antigens	Major topic
Lymphocyte Cooperation	Major topic
Animals
Antibody Formation
Binding Sites
Isoantigens
Lymph Nodes
Mice
Solubility
Spleen
T-Lymphocytes
Thymus Gland

Source PubMed

Grants0

Each grant PubMed's record writes, matched to the NIH project NIH's grant and paper links name for this paper, and each of those links the record does not write.

None in this release.

Trials0

The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.

None in this release.

Comments and corrections0

PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.

None in this release.

References29

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

Order	PMID	Title	Journal	Year	In Papers	Source
1	67,171	Immunosuppressive factor(s) extracted from lymphoid cells of nonresponder mice primed with L-glutamic acid60-L-alanine30-L-tyrosine10 (GAT) III. Immunochemical properties of the GAT-specific suppressive factor.	J Exp Med	1977	https://conductscience.org/library/papers/67171	PubMed
2	142,791	Activation of T and B lymphocytes in vitro. V. Cellular locus, metabolism and genetics of induction, and production of the allogeneic effect factor.	J Immunol	1977	https://conductscience.org/library/papers/142791	PubMed
3	142,598	Functional and genetic analysis of Ia antigens.	Cold Spring Harb Symp Quant Biol	1977	https://conductscience.org/library/papers/142598	PubMed
4	137,268	Specific binding of K- and I-region products of the H-2 complex to activated thymus-derived (T) cells belonging to different Ly subclasses.	J Exp Med	1976	https://conductscience.org/library/papers/137268	PubMed
5	325,144	Negative allogeneic effects in vitro. I. Allogeneic T cells markedly suppress the secondary antibody-forming cell response.	J Immunol	1977	https://conductscience.org/library/papers/325144	PubMed
6	323,405	Mechanism of T-cell help in the immune response to soluble protein antigens II. Reconstitution of primary and secondary in vitro immune responses to dinitrophenyl-carrier conjugates by T-cell-replacing factor.	J Exp Med	1977	https://conductscience.org/library/papers/323405	PubMed
7	302,190	Regulation of cellular and humoral immune responses by T-cell subclasses.	Cold Spring Harb Symp Quant Biol	1977	https://conductscience.org/library/papers/302190	PubMed
8	302,186	Suppressive and enhancing T-cell factors as I-region gene products: properties and the subregion assignment.	Cold Spring Harb Symp Quant Biol	1977	https://conductscience.org/library/papers/302186	PubMed
9	302,173	Selective expression of separate I-region loci in functionally different lymphocyte subpopulations.	Cold Spring Harb Symp Quant Biol	1977	https://conductscience.org/library/papers/302173	PubMed
10	302,172	Serological and functional evidence for further subdivision of the I regions of the H-2 gene complex.	Cold Spring Harb Symp Quant Biol	1977	https://conductscience.org/library/papers/302172	PubMed

1 to 10 of 29

See all 29 references

Cited by7

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 27 citations.

PMID	Title	Journal	Year	In Papers	Source
7,033,438	Role of Ia antigens in graft vs. host reactions. II. Molecular and functional analysis of T cell alloreactivity by the characterization of host Ia antigens on alloactivated donor T cells.	J Exp Med	1982	https://conductscience.org/library/papers/7033438	PubMed
6,969,778	In vitro analysis of allogeneic lymphocyte interaction. V. Identification and characterization of two components of allogeneic effect factor, one of which displays H-2-restricted helper activity and the other, T cell-growth factor activity.	J Exp Med	1981	https://conductscience.org/library/papers/6969778	PubMed
6,600,488	T cell-derived B cell growth and differentiation factors. Dichotomy between the responsiveness of B cells from adult and neonatal mice.	J Exp Med	1983	https://conductscience.org/library/papers/6600488	PubMed
6,158,551	Construction of T cell hybridomas secreting allogeneic effect factor.	J Exp Med	1980	https://conductscience.org/library/papers/6158551	PubMed
2,942,939	Photoaffinity labeling demonstrates binding between Ia molecules and nominal antigen on antigen-presenting cells.	Proc Natl Acad Sci U S A	1986	https://conductscience.org/library/papers/2942939	PubMed
311,816	Continuously proliferating allospecific T cells. I. Specificity of cooperation with allogeneic B cells in the humoral antibody response to sheep erythrocytes.	J Exp Med	1979	https://conductscience.org/library/papers/311816	PubMed
33,223	The role of H-2 and Ia antigens in graft-versus-host reactions (GVHR). Presence of host alloantigens on donor cells after GVHR and suppression of GVHR with an anti-Ia antiserum against hose Ia antigens.	J Exp Med	1979	https://conductscience.org/library/papers/33223	PubMed

Genes0

The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.

None in this release.

Drugs0

The drugs whose trials, in the Pipelines release, list the paper.

None in this release.

Data0

The data bank entries PubMed's record names. Trial numbers are under Trials.

None in this release.

Data dates

The date of each source this release read.

PubMed: 2026-11-06; PubMed
iCite: 2026-11-05; iCite
PMC's ID file: 2026-11-05; PMC's ID file
NIH RePORTER's grant and paper links: 2026-11-01; NIH RePORTER's grant and paper links
Trials: 2026-11-12
Gene search: 2026-11-11
Pipelines: 2026-09-18

Sources 11

ChEMBL, through Open TargetsCC BY-SA 3.0
ClinicalTrials.govNo license stated
HGNCCC0
iCiteCC BY 4.0
NCBI GenePublic domain (US government)
NIH RePORTER's grant and paper linksPublic domain
Open TargetsCC0 1.0
PMC's ID filePublic domain (US government)
PubMedNLM's terms
PubTator 3Public domain
UniProtCC BY 4.0

Each source's terms

ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
ClinicalTrials.govnone stated
HGNCCC0: https://www.genenames.org/about/license/
iCiteCC BY 4.0
NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
PubMedNLM's terms
PubTator 3Public domain
UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this paper from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/papers/v1/418135

GET https://conductscience.org/api/papers/v1/418135/references?page=2

API reference For AI assistants