Disease · MONDO_0007007

Ureaplasma urethritis

6 sourcesdiseases-2026-09-18-0.1.0

Cite this record

ConductScience Library. Ureaplasma urethritis. Diseases, record MONDO_0007007. Release diseases-2026-09-18-0.1.0, 18 Sept 2026. https://conductscience.org/library/diseases/MONDO_0007007

On this page

Disease

Names and IDs as Open Targets gives them. Its IDs in MeSH, Orphanet, the Disease Ontology and the NCI Thesaurus are those Open Targets states for it.

Name: Ureaplasma urethritis; Open Targets
Open Targets ID: MONDO_0007007; Open Targets
Other names: Ureaplasma Infections, Ureaplasma caused disease or disorder, Ureaplasma disease or disorder, Ureaplasma infectious disease, Ureaplasma urealyticum urethritis; Open Targets
MeSH: D016869; MeSH
Highest stage of its drugs: Phase 3, for 2 of its 2 drugs, from ClinicalTrials.gov; Open Targets

Drugs2

The drugs Open Targets' clinical reports study for the disease, the highest stage first, then the most trial reports. The stage is Open Targets', the highest any of its sources reports for the pair, and each row names the sources that report it.

Drug	ChEMBL ID	Type	Open Targets' stage	Stage reported by	Reports	Of them trials	Trials shown here	Source
AZITHROMYCIN	CHEMBL529	Small molecule	Phase 3	ClinicalTrials.gov	2	2	2	Drugs and targets
DOXYCYCLINE	CHEMBL1200699	Small molecule	Phase 3	ClinicalTrials.gov	1	1	1	Drugs and targets

Targets4

The targets ChEMBL's mechanism records give for the disease's drugs, through Open Targets, the most drugs first. A mechanism record says what a drug acts on, not that the target causes the disease.

Target	Protein	Its drugs that act on it	Mechanisms	Highest stage of those drugs	Gene in Genes	Source
MMP1	Interstitial collagenase	1	Matrix metalloproteinase-1 inhibitor	Phase 3	https://conductscience.org/library/genes/4312	Drugs and targets
MMP13	Collagenase 3	1	Matrix metalloproteinase 13 inhibitor	Phase 3	https://conductscience.org/library/genes/4322	Drugs and targets
MMP7	Matrilysin	1	Matrix metalloproteinase 7 inhibitor	Phase 3	https://conductscience.org/library/genes/4316	Drugs and targets
MMP8	Neutrophil collagenase	1	Matrix metalloproteinase 8 inhibitor	Phase 3	https://conductscience.org/library/genes/4317	Drugs and targets

Trials2

Trials an Open Targets clinical report links to the disease, posted results first, then the largest. A trial is shown when the release's checks confirm its link to the disease and Drugs and targets shows its link to one of the disease's drugs.

Trial	Title	Phase	Participants	Results first posted	Conditions	Drugs	Linked by	Source
NCT00358462	Mycoplasma Genitalium Antibiotic Susceptibility and Treatment (MEGA)	Phase 3	606	2013-03-08	Urethritis	AZITHROMYCIN, DOXYCYCLINE	Open Targets' reading, confirmed by NLM's indexing of its papers	ClinicalTrials.gov
NCT00599053	Early Versus Expectant Treatment of Ureaplasma Infection in Very Low Birth Weight Neonates	Phase 1/2	7	2012-12-31	Bacteria Infection, Respiratory Tract Infections	AZITHROMYCIN	Open Targets' reading of its record	ClinicalTrials.gov

Comparisons in its trials6

Comparisons Trial comparisons calculated in the trials shown here, most participants first. A comparison in one of these trials does not always compare a treatment for the disease, so read the two groups.

Comparison	Group 1, with the outcome	Group 2, with the outcome	Participants	Trial	Source
Active Azithromycin + Placebo Doxycycline vs Active Doxycycline + Placebo Azithromycin: serious adverse events	1 of 304	3 of 302	606	NCT00358462	Trial comparisons
Active Azithromycin + Placebo Doxycycline vs Active Doxycycline + Placebo Azithromycin: mITT Analysis of Eradication of U. Urealyticum at First Follow-up Visit	39 of 52	38 of 55	107	NCT00358462	Trial comparisons
Active Azithromycin+Placebo Doxycycline vs Active Doxycycline+Placebo Azithromycin: Clinical Cure Among Case Subjects Who Were Positive for Ureaplasmas at the Initial Study Visit	43 of 52	40 of 55	107	NCT00358462	Trial comparisons
Active Azithromycin + Placebo Doxycycline vs Active Doxycycline + Placebo Azithromycin: mITT Analysis of Eradication of M. Genitalium at First Follow-up Study Visit	15 of 38	8 of 27	65	NCT00358462	Trial comparisons
Active Azithromycin+Placebo Doxycycline vs Active Doxycycline+Placebo Azithromycin: Clinical Cure Among Case Subjects Who Were Positive for M. Genitalium at the Initial Study Visit	24 of 38	13 of 27	65	NCT00358462	Trial comparisons
Early Treatment With Azithromycin vs Expectant (Usual) Management: serious adverse events	0 of 5	0 of 2	7	NCT00599053	Trial comparisons

Papers from its trials3

The papers the trials shown here list on ClinicalTrials.gov as their results (RESULT) or as drawn from them (DERIVED), results first, newest first.

PMID	Listed as	Trials listing it	Source
25616607	DERIVED	1	PubMed
24106340	DERIVED	1	PubMed
23223595	DERIVED	1	PubMed

Data dates

The date of each source this release read.

Open Targets: 2026-09-18; Open Targets
Drug links and their checks, from Drugs and targets: 2026-09-18; Drugs and targets
ClinicalTrials.gov, from Trials: 2026-11-12; Trials
Comparisons, from Trial comparisons: 2026-03-23; Trial comparisons
PubMed, for the checks: 2026-11-06; PubMed
MeSH, for the checks: 2026-11-10; MeSH

Sources 6

ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
ChEMBL, through Open TargetsCC BY-SA 3.0
ClinicalTrials.govNo license stated
NLM's MeSHNLM's terms
Open TargetsCC0 1.0
PubMedNLM's terms

Each source's terms

ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
ClinicalTrials.govnone stated
NLM's MeSHNLM's
Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
PubMedNLM's terms

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this disease from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/diseases/v1/MONDO_0007007

GET https://conductscience.org/api/diseases/v1/MONDO_0007007/drugs

API reference For AI assistants