ConductScience.org, home
Papers
API referenceFor AI assistants

Paper · 29922827

Association Between Inherited Germline Mutations in Cancer Predisposition Genes and Risk of Pancreatic Cancer.

Hu C and 18 others. JAMA, 2018. Cited by 463 papers, by iCite.

11 sourcespapers-2026-11-12-0.1.0

Download JSON
Cite this record

ConductScience Library. Association Between Inherited Germline Mutations in Cancer Predisposition Genes and Risk of Pancreatic Cancer. Papers, record 29922827. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/29922827

On this page

Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title
Association Between Inherited Germline Mutations in Cancer Predisposition Genes and Risk of Pancreatic Cancer.
PubMed
Journal
JAMA
PubMed
Year
2018
PubMed
Publication types
Journal Article, Research Support, N.I.H., Extramural, Research Support, Non-U.S. Gov't
PubMed
Citations, by iCite
463
iCite
Relative citation ratio, by iCite
15.7
iCite
Revised in PubMed
2022-04-09
PubMed

Authors19

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

OrderAuthorForenameKindORCID iD
1Hu CChunling
2Hart SNSteven N
3Polley ECEric C
4Gnanaolivu RRohan
5Shimelis HHermela
6Lee KYKun Y
7Lilyquist JJenna
8Na JJie
9Moore RRaymond
10Antwi SOSamuel O

1 to 10 of 19Source PubMed

See all 19 authors

Topics17

NLM's MeSH indexing of the paper, its major topics first.

MeSH termMajor
Carcinoma, Pancreatic DuctalMajor topic
Genetic Predisposition to DiseaseMajor topic
Germ-Line MutationMajor topic
Pancreatic NeoplasmsMajor topic
Aged
Case-Control Studies
DNA, Neoplasm
Databases, Genetic
Female
Humans
Male
Middle Aged
Proportional Hazards Models
Registries
Risk
Sequence Analysis, DNA
Survival Analysis

Source PubMed

Grants4

Each grant PubMed's record writes, matched to the NIH project NIH's grant and paper links name for this paper, and each of those links the record does not write.

Grant, as the record writes itAgencyCountryNIH projectStated bySource
P50 CA102701NCI NIH HHSUnited StatesP50CA102701PubMed and NIHNIH RePORTER
R01 CA097075NCI NIH HHSUnited StatesR01CA097075PubMed and NIHNIH RePORTER
R01 CA192393NCI NIH HHSUnited StatesR01CA192393PubMed and NIHNIH RePORTER
R25 CA092049NCI NIH HHSUnited StatesR25CA092049PubMed and NIHNIH RePORTER

Trials0

The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.

None in this release.

Comments and corrections3

PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.

KindPMIDTitleIn PapersSource
Comment in29,922,810Germline Genetic Testing for Pancreatic Ductal Adenocarcinoma at Time of Diagnosis.https://conductscience.org/library/papers/29922810PubMed
Comment in30,002,082Study Reveals Genetics of Pancreatic Cancer.https://conductscience.org/library/papers/30002082PubMed
Comment in30,002,476Inherited pancreatic cancer risk.https://conductscience.org/library/papers/30002476PubMed

References35

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

OrderPMIDTitleJournalYearIn PapersSource
127,114,589Benefit of Surveillance for Pancreatic Cancer in High-Risk Individuals: Outcome of Long-Term Prospective Follow-Up Studies From Three European Expert Centers.J Clin Oncol2016https://conductscience.org/library/papers/27114589PubMed
212,237,281Cancer Incidence in BRCA1 mutation carriers.J Natl Cancer Inst2002https://conductscience.org/library/papers/12237281PubMed
326,483,394Prevalence of Pathogenic Mutations in Cancer Predisposition Genes among Pancreatic Cancer Patients.Cancer Epidemiol Biomarkers Prev2016https://conductscience.org/library/papers/26483394PubMed
419,861,671Risk of pancreatic cancer in families with Lynch syndrome.JAMA2009https://conductscience.org/library/papers/19861671PubMed
528,418,444Associations Between Cancer Predisposition Testing Panel Genes and Breast Cancer.JAMA Oncol2017https://conductscience.org/library/papers/28418444PubMed
625,645,574ACG clinical guideline: Genetic testing and management of hereditary gastrointestinal cancer syndromes.Am J Gastroenterol2015https://conductscience.org/library/papers/25645574PubMed
727,899,186Familial pancreatic cancer.Semin Oncol2016https://conductscience.org/library/papers/27899186PubMed
826,681,312Pathogenic and likely pathogenic variant prevalence among the first 10,000 patients referred for next-generation cancer panel testing.Genet Med2016https://conductscience.org/library/papers/26681312PubMed
924,618,464The Biological Reference Repository (BioR): a rapid and flexible system for genomics annotation.Bioinformatics2014https://conductscience.org/library/papers/24618464PubMed
1017,301,269The prevalence of BRCA2 mutations in familial pancreatic cancer.Cancer Epidemiol Biomarkers Prev2007https://conductscience.org/library/papers/17301269PubMed

1 to 10 of 35

See all 35 references

Cited by335

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 463 citations.

PMIDTitleJournalYearIn PapersSource
42,935,641Global and registry-based patterns of pancreatic cancer: GLOBOCAN 2020, CI5plus trends (2000-2017), and demographic projections to 2040.Front Oncol2026https://conductscience.org/library/papers/42935641PubMed
42,689,189A Heterogeneous Phenotypic Presentation of a PALB2 Mutation Carrier With Multiple Metachronous Primary Malignancies: A Case Report.Cureus2026https://conductscience.org/library/papers/42689189PubMed
42,654,051Emerging Precision Therapeutic Strategies in Pancreatic Ductal Adenocarcinoma: KRAS Targeting, DDR Vulnerabilities, Immune Redirection, and Tumor Microenvironment Remodeling.Pharmaceutics2026https://conductscience.org/library/papers/42654051PubMed
42,557,274Progress, challenges, and future directions of pancreatic cancer surveillance in high-risk populations.Commun Med (Lond)2026https://conductscience.org/library/papers/42557274PubMed
42,511,746Hereditary Pancreatic Cancer: Genetic Risk, Surveillance Strategies, and Therapeutic Implications.Int J Mol Sci2026https://conductscience.org/library/papers/42511746PubMed
42,507,335SEOM‑GETTHI clinical guideline for the practical management of molecular platforms (update 2026).Clin Transl Oncol2026https://conductscience.org/library/papers/42507335PubMed
42,498,744Chinese expert consensus on precision testing and molecular diagnosis of pancreatic cancer (2025).Br J Cancer2026https://conductscience.org/library/papers/42498744PubMed
42,487,270Genomic Alterations and Their Clinical Implications in Pancreatic Ductal Adenocarcinoma in a Large-Scale Chinese Cohort.Cancer Med2026https://conductscience.org/library/papers/42487270PubMed
42,440,005Focal Pancreatic Parenchymal Atrophy and Delayed Enhancement in Early Pancreatic Ductal Adenocarcinoma: A Narrative Review of Pathologic Basis, Diagnostic Pitfalls, and Evidence Limitations.Dig Dis Sci2026https://conductscience.org/library/papers/42440005PubMed
42,376,674DNA damage response inhibitors in pancreatic cancer: progress and challenges.Front Oncol2026https://conductscience.org/library/papers/42376674PubMed

1 to 10 of 335

See all 335 cited by

Genes22

The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.

GeneNCBI Gene IDLinked byIn GenesSource
ATM472PubTator's text mininghttps://conductscience.org/library/genes/472NCBI Gene
BARD1580PubTator's text mininghttps://conductscience.org/library/genes/580NCBI Gene
BRCA1672PubTator's text mininghttps://conductscience.org/library/genes/672NCBI Gene
BRCA2675PubTator's text mininghttps://conductscience.org/library/genes/675NCBI Gene
BRIP183,990PubTator's text mininghttps://conductscience.org/library/genes/83990NCBI Gene
CDH1999PubTator's text mininghttps://conductscience.org/library/genes/999NCBI Gene
CDKN2A1,029PubTator's text mininghttps://conductscience.org/library/genes/1029NCBI Gene
CHEK211,200PubTator's text mininghttps://conductscience.org/library/genes/11200NCBI Gene
FANCC2,176PubTator's text mininghttps://conductscience.org/library/genes/2176NCBI Gene
MLH14,292PubTator's text mininghttps://conductscience.org/library/genes/4292NCBI Gene

1 to 10 of 22

See all 22 genes

Drugs0

The drugs whose trials, in the Pipelines release, list the paper.

None in this release.

Data0

The data bank entries PubMed's record names. Trial numbers are under Trials.

None in this release.

Data dates

The date of each source this release read.

PubMed
2026-11-06
PubMed
iCite
2026-11-05
iCite
PMC's ID file
2026-11-05
PMC's ID file
NIH RePORTER's grant and paper links
2026-11-01
NIH RePORTER's grant and paper links
Trials
2026-11-12
Gene search
2026-11-11
Pipelines
2026-09-18

Sources 11

  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • HGNCCC0
  • iCiteCC BY 4.0
  • NCBI GenePublic domain (US government)
  • NIH RePORTER's grant and paper linksPublic domain
  • Open TargetsCC0 1.0
  • PMC's ID filePublic domain (US government)
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • HGNCCC0: https://www.genenames.org/about/license/
  • iCiteCC BY 4.0
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this paper from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/papers/v1/29922827

GET https://conductscience.org/api/papers/v1/29922827/references?page=2

API referenceFor AI assistants