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Paper · 31806905

Chronic inflammation in the etiology of disease across the life span.

Furman D and 19 others. Nat Med, 2019. Cited by 3,655 papers, by iCite.

11 sourcespapers-2026-11-12-0.1.0

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ConductScience Library. Chronic inflammation in the etiology of disease across the life span. Papers, record 31806905. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/31806905

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Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title
Chronic inflammation in the etiology of disease across the life span.
PubMed
Journal
Nat Med
PubMed
Year
2019
PubMed
Publication types
Journal Article, Research Support, N.I.H., Extramural, Research Support, Non-U.S. Gov't, Review
PubMed
Citations, by iCite
3,655
iCite
Relative citation ratio, by iCite
180
iCite
Revised in PubMed
2026-11-02
PubMed

Authors20

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

OrderAuthorForenameKindORCID iD
1Furman DDavidhttps://orcid.org/0000-0002-3654-9519
2Campisi JJudith
3Verdin EErichttps://orcid.org/0000-0003-3703-3183
4Carrera-Bastos PPedro
5Targ SSasha
6Franceschi CClaudio
7Ferrucci LLuigi
8Gilroy DWDerek W
9Fasano AAlessiohttps://orcid.org/0000-0002-2134-0261
10Miller GWGary W

1 to 10 of 20Source PubMed

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Topics13

NLM's MeSH indexing of the paper, its major topics first.

MeSH termMajor
Chronic DiseaseMajor topic
InflammationMajor topic
LongevityMajor topic
Autoimmune Diseases
Cardiovascular Diseases
Diabetes Mellitus
Humans
Life Style
Neoplasms
Neurodegenerative Diseases
Non-alcoholic Fatty Liver Disease
Renal Insufficiency, Chronic
Risk Factors

Source PubMed

Grants10

Each grant PubMed's record writes, matched to the NIH project NIH's grant and paper links name for this paper, and each of those links the record does not write.

Grant, as the record writes itAgencyCountryNIH projectStated bySource
P30 DK040561NIDDK NIH HHSUnited StatesP30DK040561PubMed and NIHNIH RePORTER
R01 HL142068NHLBI NIH HHSUnited StatesR01HL142068PubMedNIH RePORTER
R01 AR042527NIAMS NIH HHSUnited StatesR01AR042527PubMedNIH RePORTER
P01 AG036695NIA NIH HHSUnited StatesP01AG036695PubMedNIH RePORTER
R01 HL117913NHLBI NIH HHSUnited StatesR01HL117913PubMedNIH RePORTER
R01 AR073248NIAMS NIH HHSUnited StatesR01AR073248PubMedNIH RePORTER
R01 AI108906NIAID NIH HHSUnited StatesR01AI108906PubMedNIH RePORTER
K08 MH103443NIMH NIH HHSUnited StatesK08MH103443PubMed and NIHNIH RePORTER
R01 AG055755NIA NIH HHSUnited StatesR01AG055755PubMedNIH RePORTER
P01 HL129941NHLBI NIH HHSUnited StatesP01HL129941PubMedNIH RePORTER

Trials9

The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.

TrialTitleThe trial lists it asNamed in the paper's recordSource
NCT05050812The Grounded Brain: How Sleeping Grounded Affects Memory and PerceptionsResultsClinicalTrials.gov
NCT06294145Effects of a Wellbeing Intervention on Inflammation Through Reward and Threat ProcessesBackgroundClinicalTrials.gov
NCT06540612Effects of Aerobic Exercise on Cancer-Related Biomarkers, Functional Capacity, Cognitive Status and Quality of Life in Women With Breast CancerResultsClinicalTrials.gov
NCT06635278Mindfulness Meditation: Alleviating Symptoms and Inflammation in NursesResultsClinicalTrials.gov
NCT07109817Desloratadine to Prevent Taxane-induced Peripheral Neuropathy in Patients With Breast CancerBackgroundClinicalTrials.gov
NCT07248891Type 2 Diabetes and Associated Factors in MexicoResultsClinicalTrials.gov
NCT07282964Mindful Moms, Mindful Meals (MMMM) StudyBackgroundClinicalTrials.gov
NCT07309536Mediterranean Diet Uptake and Nutrition on Child Health, Inflammation, and Early-life Symbiosis (MUNCHIES) StudyBackgroundClinicalTrials.gov
NCT07862049What is the Effect of Increased Consumption of Fruit Juice on Exercise Capacity and Inflammatory Biomarkers?BackgroundClinicalTrials.gov

Comments and corrections0

PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.

None in this release.

References156

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

OrderPMIDTitleJournalYearIn PapersSource
128,092,664Expression of specific inflammasome gene modules stratifies older individuals into two extreme clinical and immunological states.Nat Med2017https://conductscience.org/library/papers/28092664PubMed
228,722,720A guiding map for inflammation.Nat Immunol2017https://conductscience.org/library/papers/28722720PubMed
325,449,576Understanding inflammation, its regulation, and relevance for health: a top scientific and public priority.Brain Behav Immun2015https://conductscience.org/library/papers/25449576PubMed
421,787,044Psychological stress in childhood and susceptibility to the chronic diseases of aging: moving toward a model of behavioral and biological mechanisms.Psychol Bull2011https://conductscience.org/library/papers/21787044PubMed
529,673,874Origins of lifetime health around the time of conception: causes and consequences.Lancet2018https://conductscience.org/library/papers/29673874PubMed
628,673,401An exposome perspective: Early-life events and immune development in a changing world.J Allergy Clin Immunol2017https://conductscience.org/library/papers/28673401PubMed
725,723,161Homeostasis, inflammation, and disease susceptibility.Cell2015https://conductscience.org/library/papers/25723161PubMed
820,210,843Energy regulation and neuroendocrine-immune control in chronic inflammatory diseases.J Intern Med2010https://conductscience.org/library/papers/20210843PubMed
926,044,543Evolutionary medicine and bone loss in chronic inflammatory diseases--A theory of inflammation-related osteopenia.Semin Arthritis Rheum2015https://conductscience.org/library/papers/26044543PubMed
1026,817,483Chronic inflammatory systemic diseases: An evolutionary trade-off between acutely beneficial but chronically harmful programs.Evol Med Public Health2016https://conductscience.org/library/papers/26817483PubMed

1 to 10 of 156

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Cited by2,662

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 3,655 citations.

PMIDTitleJournalYearIn PapersSource
42,985,416Anti-atherosclerotic effects of Allium hookeri and its mechanism in high fat/high cholesterol-induced obese C57BL/6 mice.Food Nutr Res2026https://conductscience.org/library/papers/42985416PubMed
42,985,198Biomarkers for the diagnosis and management of cardiovascular-kidney-metabolic syndrome: recent advances and prospects for clinical application.Front Endocrinol (Lausanne)2026https://conductscience.org/library/papers/42985198PubMed
42,978,697Hupehenine suppresses tumor cell phenotypes and modulates macrophage marker profiles in a diabeticmimetic colorectal cancer model.Front Pharmacol2026https://conductscience.org/library/papers/42978697PubMed
42,974,276High sensitivity-C-reactive protein variability and risk of cancer incidence: A longitudinal prospective cohort study cancer.Exp Ther Med2026https://conductscience.org/library/papers/42974276PubMed
42,965,602Making hormesis visible in new approach methodologies (NAMs): a framework for botanical mixtures, biological context, and risk interpretation.Arch Toxicol2026https://conductscience.org/library/papers/42965602PubMed
42,964,879Social isolation, loneliness and subsequently developing risk for autoimmune diseases: A prospective study from UK Biobank.Brain Behav Immun Health2026https://conductscience.org/library/papers/42964879PubMed
42,964,653From bodily signals to safe action: an interoceptive self-regulation loop for whole-person health.Front Public Health2026https://conductscience.org/library/papers/42964653PubMed
42,959,208Association of the red cell distribution width/albumin ratio with 6-month readmission risk in heart failure patients.Front Cardiovasc Med2026https://conductscience.org/library/papers/42959208PubMed
42,958,681Pharmacological advances of alkaloids from Traditional Chinese Medicine against pulmonary fibrosis: focus on anti-inflammatory mechanisms.J Tradit Chin Med2026https://conductscience.org/library/papers/42958681PubMed
42,958,623Systemic Inflammatory Indices and Hearing Loss in U.S. Adults Aged 40-85 Years: A Serial Cross-Sectional Study 1999-2020.Immun Inflamm Dis2026https://conductscience.org/library/papers/42958623PubMed

1 to 10 of 2,662

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Genes13

The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.

GeneNCBI Gene IDLinked byIn GenesSource
ALB213PubTator's text mininghttps://conductscience.org/library/genes/213NCBI Gene
CCL26,347PubTator's text mininghttps://conductscience.org/library/genes/6347NCBI Gene
CD4920PubTator's text mininghttps://conductscience.org/library/genes/920NCBI Gene
CD8A925PubTator's text mininghttps://conductscience.org/library/genes/925NCBI Gene
CRP1,401PubTator's text mininghttps://conductscience.org/library/genes/1401NCBI Gene
HIF1A3,091PubTator's text mininghttps://conductscience.org/library/genes/3091NCBI Gene
HP3,240PubTator's text mininghttps://conductscience.org/library/genes/3240NCBI Gene
IFNA13,439PubTator's text mininghttps://conductscience.org/library/genes/3439NCBI Gene
IL1B3,553PubTator's text mininghttps://conductscience.org/library/genes/3553NCBI Gene
IL1R13,554PubTator's text mininghttps://conductscience.org/library/genes/3554NCBI Gene

1 to 10 of 13

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Drugs0

The drugs whose trials, in the Pipelines release, list the paper.

None in this release.

Data0

The data bank entries PubMed's record names. Trial numbers are under Trials.

None in this release.

Data dates

The date of each source this release read.

PubMed
2026-11-06
PubMed
iCite
2026-11-05
iCite
PMC's ID file
2026-11-05
PMC's ID file
NIH RePORTER's grant and paper links
2026-11-01
NIH RePORTER's grant and paper links
Trials
2026-11-12
Gene search
2026-11-11
Pipelines
2026-09-18

Sources 11

  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • HGNCCC0
  • iCiteCC BY 4.0
  • NCBI GenePublic domain (US government)
  • NIH RePORTER's grant and paper linksPublic domain
  • Open TargetsCC0 1.0
  • PMC's ID filePublic domain (US government)
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • HGNCCC0: https://www.genenames.org/about/license/
  • iCiteCC BY 4.0
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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