Paper · 34508258
The MYC oncogene - the grand orchestrator of cancer growth and immune evasion.
Dhanasekaran R and 5 others. Nat Rev Clin Oncol, 2022. Cited by 859 papers, by iCite.
11 sourcespapers-2026-11-12-0.1.0
Cite this record
ConductScience Library. The MYC oncogene - the grand orchestrator of cancer growth and immune evasion. Papers, record 34508258. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/34508258
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Paper
PubMed's record of the paper, with iCite's citation figures. No abstract is shown.
- Publication types
- Journal Article, Research Support, N.I.H., Extramural, Research Support, Non-U.S. Gov't, Review
- PubMed
Topics5
NLM's MeSH indexing of the paper, its major topics first.
| MeSH term | Major |
|---|---|
| Genes, myc | Major topic |
| Immune Evasion | Major topic |
| Neoplasms | Major topic |
| Oncogenes | Major topic |
| Humans |
Source PubMed
Grants6
Each grant PubMed's record writes, matched to the NIH project NIH's grant and paper links name for this paper, and each of those links the record does not write.
| Grant, as the record writes it | Agency | Country | NIH project | Stated by | Source |
|---|---|---|---|---|---|
| K08 CA222676 | NCI NIH HHS | United States | K08CA222676 | PubMed and NIH | NIH RePORTER |
| R35 CA253180 | NCI NIH HHS | United States | R35CA253180 | PubMed and NIH | NIH RePORTER |
| R01CA184384 | NIH | NIH RePORTER | |||
| R01CA208735 | NIH | NIH RePORTER | |||
| T32CA196585 | NIH | NIH RePORTER | |||
| U01CA188383 | NIH | NIH RePORTER |
Trials1
The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.
| Trial | Title | The trial lists it as | Named in the paper's record |
|---|---|---|---|
| NCT06758700 | Post-line Treatment With Teniposide for c-Myc-driven Extensive-stage Small Cell Lung Cancer | Background |
Source ClinicalTrials.gov
Comments and corrections0
PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.
None in this release.
References212
The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.
| Order | PMID | Title | Journal | Year | In Papers | Source |
|---|---|---|---|---|---|---|
| 1 | 19,029,958 | Reflecting on 25 years with MYC. | Nat Rev Cancer | 2008 | https://conductscience.org/library/papers/19029958 | PubMed |
| 2 | 22,464,321 | MYC on the path to cancer. | Cell | 2012 | https://conductscience.org/library/papers/22464321 | PubMed |
| 3 | 29,596,783 | Pan-cancer Alterations of the MYC Oncogene and Its Proximal Network across the Cancer Genome Atlas. | Cell Syst | 2018 | https://conductscience.org/library/papers/29596783 | PubMed |
| 4 | 26,383,138 | MYC: connecting selective transcriptional control to global RNA production. | Nat Rev Cancer | 2015 | https://conductscience.org/library/papers/26383138 | PubMed |
| 5 | 24,384,812 | An overview of MYC and its interactome. | Cold Spring Harb Perspect Med | 2014 | https://conductscience.org/library/papers/24384812 | PubMed |
| 6 | 15,681,534 | Relationship between MYCN copy number and expression in rhabdomyosarcomas and correlation with adverse prognosis in the alveolar subtype. | J Clin Oncol | 2005 | https://conductscience.org/library/papers/15681534 | PubMed |
| 7 | 21,882,282 | Molecular profiling reveals frequent gain of MYCN and anaplasia-specific loss of 4q and 14q in Wilms tumor. | Genes Chromosomes Cancer | 2011 | https://conductscience.org/library/papers/21882282 | PubMed |
| 8 | 31,260,412 | N-Myc-mediated epigenetic reprogramming drives lineage plasticity in advanced prostate cancer. | J Clin Invest | 2019 | https://conductscience.org/library/papers/31260412 | PubMed |
| 9 | 29,358,508 | The Expanding World of N-MYC-Driven Tumors. | Cancer Discov | 2018 | https://conductscience.org/library/papers/29358508 | PubMed |
| 10 | 29,028,833 | Merkel cell polyomavirus recruits MYCL to the EP400 complex to promote oncogenesis. | PLoS Pathog | 2017 | https://conductscience.org/library/papers/29028833 | PubMed |
1 to 10 of 212
See all 212 referencesCited by650
The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 859 citations.
| PMID | Title | Journal | Year | In Papers | Source |
|---|---|---|---|---|---|
| 42,979,412 | Targeting RSK2 reverses endocrine resistance in ER-positive breast cancer via inhibiting the c-Myc-ERBB4 signaling pathway. | Acta Pharm Sin B | 2026 | https://conductscience.org/library/papers/42979412 | PubMed |
| 42,979,122 | Activation of KIF18B-MYC axis by autophagic CUL3 degradation promotes copper imbalance essential for gastric cancer progression. | Acta Pharm Sin B | 2026 | https://conductscience.org/library/papers/42979122 | PubMed |
| 42,966,755 | Conformational heterogeneity: a fundamental mechanism of adaptive phenotypic plasticity and therapeutic resistance. | Br J Cancer | 2026 | https://conductscience.org/library/papers/42966755 | PubMed |
| 42,958,559 | Targeted protein degradation in cancer: strategies for undruggable targets and progress towards clinical translation. | Biomark Res | 2026 | https://conductscience.org/library/papers/42958559 | PubMed |
| 42,957,722 | RuPHOTACs provide photocontrol over protein degradation with optimized properties for biological applications. | Nat Commun | 2026 | https://conductscience.org/library/papers/42957722 | PubMed |
| 42,926,972 | PathVista Integrates Cellular Foundation Models with Multiscale Histopathology for Colorectal Cancer Prognosis and Molecular Stratification. | Res Sq | 2026 | https://conductscience.org/library/papers/42926972 | PubMed |
| 42,924,439 | NEAT1 remodeling rewires the MYC degradation pathway. | Nucleic Acids Res | 2026 | https://conductscience.org/library/papers/42924439 | PubMed |
| 42,916,388 | Probing the pH- and Voltage-Driven Intramolecular Folding Dynamics of the c-MycC52 Promoter i-Motif at the Single-Molecule Level. | Anal Chem | 2026 | https://conductscience.org/library/papers/42916388 | PubMed |
| 42,856,523 | TET loss of function selects for aneuploidies that confer a proliferative advantage. | bioRxiv | 2026 | https://conductscience.org/library/papers/42856523 | PubMed |
| 42,850,216 | p53 wild-type/low c-Myc-expressing ONS76 pediatric medulloblastoma cells become senescent after gamma-irradiation and can be eliminated by senolytic substances. | Cell Death Discov | 2026 | https://conductscience.org/library/papers/42850216 | PubMed |
1 to 10 of 650
See all 650 cited byGenes30
The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.
| Gene | NCBI Gene ID | Linked by | In Genes | Source |
|---|---|---|---|---|
| APC | 324 | PubTator's text mining | https://conductscience.org/library/genes/324 | NCBI Gene |
| CCL2 | 6,347 | PubTator's text mining | https://conductscience.org/library/genes/6347 | NCBI Gene |
| CD274 | 29,126 | PubTator's text mining | https://conductscience.org/library/genes/29126 | NCBI Gene |
| CD47 | 961 | PubTator's text mining | https://conductscience.org/library/genes/961 | NCBI Gene |
| CTNNB1 | 1,499 | PubTator's text mining | https://conductscience.org/library/genes/1499 | NCBI Gene |
| DNER | 92,737 | PubTator's text mining | https://conductscience.org/library/genes/92737 | NCBI Gene |
| EPHB2 | 2,048 | PubTator's text mining | https://conductscience.org/library/genes/2048 | NCBI Gene |
| FBXW7 | 55,294 | PubTator's text mining | https://conductscience.org/library/genes/55294 | NCBI Gene |
| IL13 | 3,596 | PubTator's text mining | https://conductscience.org/library/genes/3596 | NCBI Gene |
| MAP2K7 | 5,609 | PubTator's text mining | https://conductscience.org/library/genes/5609 | NCBI Gene |
1 to 10 of 30
See all 30 genesDrugs0
The drugs whose trials, in the Pipelines release, list the paper.
None in this release.
Data0
The data bank entries PubMed's record names. Trial numbers are under Trials.
None in this release.
Data dates
The date of each source this release read.
- Trials
- 2026-11-12
- Gene search
- 2026-11-11
- Pipelines
- 2026-09-18
Sources 11
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- HGNCCC0
- iCiteCC BY 4.0
- NCBI GenePublic domain (US government)
- NIH RePORTER's grant and paper linksPublic domain
- Open TargetsCC0 1.0
- PMC's ID filePublic domain (US government)
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- HGNCCC0: https://www.genenames.org/about/license/
- iCiteCC BY 4.0
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
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