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Paper · 34830836

Biological Significance and Targeting of the FGFR Axis in Cancer.

Chioni AM and 1 other. Cancers (Basel), 2021. Cited by 56 papers, by iCite.

11 sourcespapers-2026-11-12-0.1.0

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ConductScience Library. Biological Significance and Targeting of the FGFR Axis in Cancer. Papers, record 34830836. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/34830836

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Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title
Biological Significance and Targeting of the FGFR Axis in Cancer.
PubMed
Journal
Cancers (Basel)
PubMed
Year
2021
PubMed
Publication types
Journal Article, Review
PubMed
Citations, by iCite
56
iCite
Relative citation ratio, by iCite
3.3
iCite
Revised in PubMed
2024-08-18
PubMed

Authors2

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

OrderAuthorForenameKindORCID iD
1Chioni AMAthina-Myrto
2Grose RPRichard Phttps://orcid.org/0000-0002-4738-0173

Source PubMed

Topics0

NLM's MeSH indexing of the paper, its major topics first.

None in this release.

Grants0

Each grant PubMed's record writes, matched to the NIH project NIH's grant and paper links name for this paper, and each of those links the record does not write.

None in this release.

Trials0

The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.

None in this release.

Comments and corrections0

PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.

None in this release.

References241

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

OrderPMIDTitleJournalYearIn PapersSource
126,903,404Regulation of FGF signaling: Recent insights from studying positive and negative modulators.Semin Cell Dev Biol2016https://conductscience.org/library/papers/26903404PubMed
220,016,912Conserved intron positions in FGFR genes reflect the modular structure of FGFR and reveal stepwise addition of domains to an already complex ancestral FGFR.Dev Genes Evol2009https://conductscience.org/library/papers/20016912PubMed
311,031,111Characterization of a novel protein (FGFRL1) from human cartilage related to FGF receptors.Genomics2000https://conductscience.org/library/papers/11031111PubMed
410,490,103Structural basis for FGF receptor dimerization and activation.Cell1999https://conductscience.org/library/papers/10490103PubMed
516,597,617Receptor specificity of the fibroblast growth factor family. The complete mammalian FGF family.J Biol Chem2006https://conductscience.org/library/papers/16597617PubMed
620,066,096Vertebrate limb development: moving from classical morphogen gradients to an integrated 4-dimensional patterning system.Cold Spring Harb Perspect Biol2009https://conductscience.org/library/papers/20066096PubMed
724,780,002The ins and outs of fibroblast growth factor receptor signalling.Clin Sci (Lond)2014https://conductscience.org/library/papers/24780002PubMed
88,375,495A novel form of FGF receptor-3 using an alternative exon in the immunoglobulin domain III.FEBS Lett1993https://conductscience.org/library/papers/8375495PubMed
930,326,563BGJ398, A Pan-FGFR Inhibitor, Overcomes Paclitaxel Resistance in Urothelial Carcinoma with FGFR1 Overexpression.Int J Mol Sci2018https://conductscience.org/library/papers/30326563PubMed
1023,465,883Extracellular modulation of Fibroblast Growth Factor signaling through heparan sulfate proteoglycans in mammalian development.Curr Opin Genet Dev2013https://conductscience.org/library/papers/23465883PubMed

1 to 10 of 241

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Cited by37

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 56 citations.

PMIDTitleJournalYearIn PapersSource
42,681,846Synthetic Heparan Sulfate-like Oligosaccharides as Tools to Decipher Growth Factor Recognition.J Med Chem2026https://conductscience.org/library/papers/42681846PubMed
42,633,326Advances in FGF/FGFR Signaling: Implications for Disease and Therapy.MedComm (2020)2026https://conductscience.org/library/papers/42633326PubMed
42,372,295Continuous multi-omics pathway enrichment analysis resolves hidden functional heterogeneity.Brief Bioinform2026https://conductscience.org/library/papers/42372295PubMed
42,326,010FGFR inhibitor resistance in cervical cancer: a role for integrin α2 and mTOR signalling.Front Cell Dev Biol2026https://conductscience.org/library/papers/42326010PubMed
41,972,170The FGF-FGFR axis as an immune-metabolic rheostat in gastrointestinal inflammation and cancer.Front Immunol2026https://conductscience.org/library/papers/41972170PubMed
41,764,695Ligand-based graph neural network, molecular dynamics and biological evaluation for identification of potential FGFR1 kinase inhibitors.Mol Divers2026https://conductscience.org/library/papers/41764695PubMed
41,681,916FGFR Testing in Metastatic Urothelial Carcinoma-Who, When, and How to Test.Cancers (Basel)2026https://conductscience.org/library/papers/41681916PubMed
41,584,352Unraveling the FGFR-RNA splicing axis: Mechanisms, oncogenic crosstalks and innovations for therapeutic purpose.Acta Pharm Sin B2026https://conductscience.org/library/papers/41584352PubMed
41,083,779The hypoxic ECM and neutrophils in MIBC immunotherapy resistance.Nat Rev Urol2026https://conductscience.org/library/papers/41083779PubMed
41,029,365Modification of adipose mass by targeting distal enhancers of Ptrf.BMC Biol2025https://conductscience.org/library/papers/41029365PubMed

1 to 10 of 37

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Genes79

The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.

GeneNCBI Gene IDLinked byIn GenesSource
ANGPT2285PubTator's text mininghttps://conductscience.org/library/genes/285NCBI Gene
ANO363,982PubTator's text mininghttps://conductscience.org/library/genes/63982NCBI Gene
ANOS13,730PubTator's text mininghttps://conductscience.org/library/genes/3730NCBI Gene
BCL2596PubTator's text mininghttps://conductscience.org/library/genes/596NCBI Gene
BCL2L1110,018PubTator's text mininghttps://conductscience.org/library/genes/10018NCBI Gene
BCR613PubTator's text mininghttps://conductscience.org/library/genes/613NCBI Gene
BICC180,114PubTator's text mininghttps://conductscience.org/library/genes/80114NCBI Gene
CBL867PubTator's text mininghttps://conductscience.org/library/genes/867NCBI Gene
CBLL2158,506PubTator's text mininghttps://conductscience.org/library/genes/158506NCBI Gene
CCDC68,030PubTator's text mininghttps://conductscience.org/library/genes/8030NCBI Gene

1 to 10 of 79

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Drugs0

The drugs whose trials, in the Pipelines release, list the paper.

None in this release.

Data0

The data bank entries PubMed's record names. Trial numbers are under Trials.

None in this release.

Data dates

The date of each source this release read.

PubMed
2026-11-06
PubMed
iCite
2026-11-05
iCite
PMC's ID file
2026-11-05
PMC's ID file
NIH RePORTER's grant and paper links
2026-11-01
NIH RePORTER's grant and paper links
Trials
2026-11-12
Gene search
2026-11-11
Pipelines
2026-09-18

Sources 11

  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • HGNCCC0
  • iCiteCC BY 4.0
  • NCBI GenePublic domain (US government)
  • NIH RePORTER's grant and paper linksPublic domain
  • Open TargetsCC0 1.0
  • PMC's ID filePublic domain (US government)
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • HGNCCC0: https://www.genenames.org/about/license/
  • iCiteCC BY 4.0
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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